Bilateral idiopathic granulomatous mastitis

Abstract

Bilateral IGMs have a higher rate of more relapse and greater resistance to medical therapies than do unilateral IGMs. Surgical management should be avoided unless all medical treatment options have been exhausted. Nevertheless, expectant management seems a rational option for the treatment of bilateral IGM.

Granulomatous lobular mastitis: Clinical update and case study

“…Patients with GM are typically women of childbearing age; a median age of approximately 35 years has been a relatively consistent finding. [2][3][4][5] Hormonal factors are hypothesised to contribute because of the association with parity, current pregnancy and the oral contraceptive pill. GM is rarely seen in nulliparous women, and the majority of patients are within five years of a pregnancy, supporting the theory of a hormonal aetiology.…”

Steroids administered after vacuum-assisted biopsy in the management of idiopathic granulomatous mastitis

“…Velidedeoglu et al 13 reported a relatively large series, with 10 patients diagnosed with bilateral IGM. Others reported left or equal involvement 12 14…”

“…Velidedeoglu et al 13 found that patients with bilateral IGM have a higher rate of relapse and greater resistance to medical therapies than patients with unilateral IGM. In our study, five patients with IGM had bilateral involvement and four patients had recurrence.…”

Granulomatous Lobular Mastitis: Antituberculous Treatment and Outcome in 22 Patients

“…Velidedeoglu et al . [23] also found that antituberculous treatment was effective in the treatment of a patient with bilateral disease. Recently, Farouk et al [24] reported that in their prospective study including 30 GLM patients, rifampicin (300 mg twice daily for 6-9 months) was an effective therapy.…”