Bilateral microphthalmos and orbital cyst

Demirci, Hakan; Singh, Arun D.; Shields, Jerry A.; Shields, Carol L.; Eagle, Ralph C.

doi:10.1038/sj.eye.6700318

Cited by 16 publications

(13 citation statements)

References 7 publications

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“…Microphthalmic eyes may develop angle closure glaucoma, which may cause loss of what vision does exist and can also cause pain. 17 Children with chorioretinal coloboma and their parents should be aware of the increased risk of retinal detachment and receive instructions for prompt attendance in the case of any alteration in vision. 18 Glasses are prescribed for refractive error, protection, and sometimes for providing lenses to minimise cosmetic defect (such as plus lenses to increase the size of a microphthalmic eye or prisms to equalise a height discrepancy).…”

Section: Long-term Managementmentioning

confidence: 99%

A practical guide to the management of anophthalmia and microphthalmia

Ragge

Subak-Sharpe

Collin

2007

Eye

109

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Section: Long-term Managementmentioning

confidence: 99%

A practical guide to the management of anophthalmia and microphthalmia

Ragge

Subak-Sharpe

Collin

2007

Eye

109

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“…[ 1 , 2 , 5 , 6 , 8 , 9 ] The cysts locating retrobulbarly had much less influence on the conjunctiva sac and the eyelids. [ 3 , 7 ] According to our research, the cysts have a predilection for retrobulbar space, but most of the reported cases were large anteriorly growing cysts. The reason may be that the anterior cysts are obvious clinically, while some posterior cysts could be neglected without high-quality imaging examination.…”

Section: Discussionmentioning

confidence: 83%

Digital Evaluation of Orbital Cyst Associated with Microphthalmos: Characteristics and Their Relationship with Orbital Volume

et al. 2016

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PurposeTo study the characteristics of orbital cyst associated with microphthalmos in a group of Chinese patients, and to analyze the relationship between orbital cyst and orbital volume.DesignCross-sectional comparative study.Participants120 patients who were diagnosed as unilateral clinical blind microphthalmos, in which 20 patients had orbital cyst in the affected eye.MethodParticipants had computed tomography (CT) scan. CT images were analyzed with a computer-aided software.Main Outcome MeasuresVolume and position of orbital cyst, microphthalmic to contralateral ratio (MCR) of orbital volume, height and depth and orbital rim displacement.Results38.1% of the cysts located anterior to or at the equator of the globe, 75% of which located infratemporally and all of which were outside the muscle cone. Most (84.6%) of the posterior cysts were inside the muscle cone. The anterior cysts were larger than the posterior cysts (p = 0.005). MCR of orbital volume (p<0.001), height (p = 0.004) and width (p = 0.043) were significantly higher in patients with orbital cyst than controls. For patients with orbital cyst, larger cyst-plus-globe volume of the affected eye was associated with higher MCR of orbital volume (r = 0.630, p = 0.003). Patients with large cyst-plus-globe volume had higher MCR of orbital volume (p = 0.002), height (p = 0.014), width (p = 0.005) and depth (p = 0.002) and less displacement in inferior (p = 0.004) orbital rim, compared with patients with small cyst-plus-globe volume, but the differences between patients with small cyst-plus-globe volume and patients without cyst were not significant.ConclusionsMicrophthalmic eyes with large cyst-plus-globe volume showed better similarity with the contralateral eyes, comparing with microphthalmic eyes without orbital cyst or with small cyst-plus-globe volume. It suggested that the existence of orbital cysts (especially large cysts) in microphthalmic eyes might play a positive role in the orbital development.

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“…They are frequently responsible for microphthalmos, presumably secondary to the abnormal development of the orbital cavity during embryogenesis (Chaudhry et al, 2004;Demirci et al, 2002Demirci et al, , 2003Lincoff et al, 1988). Associated features accounting for visual 98 Adult without Microphthalmos with Orbital Cyst loss include retinoschisis (Lincoff et al, 1988), nonrhegmatogenous retinal detachment (Bonnet, 1991), lens opacities, optic nerve atrophy or optic nerve hypoplasia.…”

Section: Discussionmentioning

confidence: 97%