Bilateral Orchiectomy for the Surgical Treatment of Complete Androgen Insensitivity Syndrome: Patient Outcome after 1 Year of Follow-up

Abstract

Patients with complete AIS should undergo postpubertal gonadectomy because of an increased risk for malignant transformation of the testicles, and this can be performed safely via small-caliber laparoscopy. Attention to psychological considerations in such patients is important to maximize long-term success.

Complete androgen insensitivity syndrome: Review of four cases

“…The main reason for prepubertal gonadectomy is the risk of malignancy in CAIS -which is considerable and occurs at later age. Although it is known that the patients over 30 are at the greatest risk for malignancy development [10][11][12] in recent literature malignant alteration of retained testicles has been reported in both prepubertal and in adult patients [13,14]. Today the laparoscopical method is a "gold standard" as a diagnostic and surgical approach [15].…”