Bilateral parotid swelling: A review

Mandel, Louis; Surattanont, Farisa

doi:10.1067/moe.2002.121163

Cited by 111 publications

(45 citation statements)

References 141 publications

(180 reference statements)

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“…Bilateral painless and prolonged parotid swelling without signs of excretory abnormalities may indicate sialoadenosis (sialosis). It is a disorder usually associated with liver dysfunction, diabetes, or malnutrition 2 . If chronic diffuse swelling associated with "dry mouth" is observed, conditions leading to progressive parenchymal gland infiltration should be considered: Sjögren's syndrome, HIV sialadenitis and radiation-induced sialadenitis.…”

Section: Clinical Scenariosmentioning

confidence: 99%

Diagnostic work-up in obstructive and inflammatory salivary gland disorders

Ugga

Ravanelli

Pallottino

et al. 2017

Acta Otorhinolaryngol Ital

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La patologia infiammatoria ed ostruttiva delle ghiandole salivari riconosce molteplici eziologie con coinvolgimento del parenchima ghiandolare e/o del sistema escretore. Il quadro clinico è essenziale per indirizzare lintegrazione diagnostica con adeguate metodiche di imaging. Sulla base dellanamnesi e dellesame obiettivo, possono riconoscersi quattro scenari clinici: (1) tumefazione acuta generalizzata delle ghiandole salivari maggiori; (2) tumefazione acuta di ununica ghiandola salivare maggiore; (3) tumefazione cronica generalizzata delle ghiandole salivari maggiori associata o meno a xerostomia; (4) tumefazione cronica o persistente di una singola ghiandola salivare maggiore. Lalgoritmo diagnostico per la scelta della metodica di imaging più appropriata dipende quindi dallo scenario clinico. Limaging è essenziale per confermare la diagnosi clinica, per definire lestensione della patologia ed identificare eventuali complicanze. Le metodiche di imaging disponibili includono lecografia, la tomografia computerizzata e la risonanza magnetica, anche con scialografia RM.

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Section: Clinical Scenariosmentioning

confidence: 99%

Diagnostic work-up in obstructive and inflammatory salivary gland disorders

Ugga

Ravanelli

Pallottino

et al. 2017

Acta Otorhinolaryngol Ital

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“…In the literature, most of the cases of sialadenosis are related to chronic alcohol intake, although there have also been case reports related to anorexia nervosa and bulimia. 2,6 Idiopathic sialadenosis is rarely seen or reported. According to our knowledge, there has been only one case of this condition published worldwide over the last 30 years.…”

Section: Case Reportmentioning

confidence: 99%

“…1 The disease occurs more frequently in adults, affecting male and female in equal frequency. 1,2 The etiology of sialadenosis is unknown; however, the reports have described this condition in association with systemic diseases such as diabetes mellitus, alcoholism, chronic malnutrition, antihypertensive therapy, bulimia, and HIV infection. [1][2][3][4][5][6] Diagnosis is based mainly on the clinical findings.…”

Section: Introductionmentioning

confidence: 99%

“…1,2 The etiology of sialadenosis is unknown; however, the reports have described this condition in association with systemic diseases such as diabetes mellitus, alcoholism, chronic malnutrition, antihypertensive therapy, bulimia, and HIV infection. [1][2][3][4][5][6] Diagnosis is based mainly on the clinical findings. 2 Ultrasound and computed tomography are very useful tools not only to confirm a clinical diagnosis of sialadenosis, but also to rule out other diseases, specifically neoplasias.…”

Section: Introductionmentioning

confidence: 99%

“…[1][2][3][4][5][6] Diagnosis is based mainly on the clinical findings. 2 Ultrasound and computed tomography are very useful tools not only to confirm a clinical diagnosis of sialadenosis, but also to rule out other diseases, specifically neoplasias. [5][6][7] Fine needle aspiration biopsy may be useful in some cases to differentiate an inflammatory mass from a neoplasia.…”

Section: Introductionmentioning

confidence: 99%

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Idiopathic sialadenosis involving parotid and submandibular glands. A case report.

et al. 2015

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| This article reports a case in which an adult black male patient was diagnosed as having sialadenosis of idiopathic type, since computed tomography, clinical, and laboratory examinations did not disclose any other abnormalities that could be associated with the glandular swelling observed in the patient. As this condition is quite harmless, requiring no intervention, unless for aesthetic reason, the patient was dismissed, being monitored sporadically. But after 8 months since the first consultation the patient was diagnosed as having an advanced esophageal squamous cell carcinoma, and eventually died of this disease. Therefore, this report raises the question whether there was any relation with the sialadenosis and the esophageal carcinoma. This question is very speculative, but it stands as a notice for clinicians in future cases of idiopathic sialadenosis to evaluate the patient for an underlying malignant disease.DESCRIPTORS | Parotid Gland; Pathology; Salivary Glands; Salivary Gland Diseases; Sialadenosis.RESUMO | Sialoadenose do tipo idiopático envolvendo as glândulas parótida e submandibular: relato de caso • Este relato descreve o caso de um paciente adulto negro diagnosticado com uma sialoadenose do tipo idiopático, uma vez que exames clínicos, de tomografia computadorizada e testes laboratoriais não revelaram qualquer outra anormalidade que pudesse ser associada ao aumento de volume glandular por ele apresentado. Considerando que essa condição é bastante benigna, não requerendo qualquer outra intervenção exceto por razões estéticas, o paciente foi dispensado e orientado a retornar para controles esporádicos. Entretanto, oito meses após sua consulta inicial, o paciente recebeu um diagnóstico de carcinoma de células escamosas avançado no esôfago, que o levou a óbito. Esse relato, então, levantou o questionamento de alguma relação entre a sialoadenose e o carcinoma esofágico. Essa questão é obviamente especulativa, mas permanece como um aviso aos clínicos para, em futuros casos de sialoadenose idiopática, avaliar o paciente para uma doença maligna subjacente.

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The anatomical pattern of ductal arborization in parotid glands using cone‐beam computerized sialography

Amiel,

Shauly,

Istoyler

et al. 2024

Clinical Anatomy

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Cone‐Beam Computed Tomography‐Sialography (Sialo‐CBCT) is used to demonstrate salivary ductal structure. This study aimed to conduct a volumetric analysis of the anatomical morphology of Normal‐Appearing Glands (NAGs) in parotid sialo‐CBCT. Our retrospective study included 14 parotid sialo‐CBCT scans interpreted as NAGs in 11 patients with salivary gland impairment. The main duct length and width, as well as number and width of secondary and tertiary ducts were manually evaluated. We found that the main parotid duct showed an average width of 1.39 mm, 1.15 mm, and 0.98 mm, for the proximal, middle and distal thirds, respectively. The arborization pattern showed approximately 20% more tertiary (average number 11.1 ± 2.7) than secondary ducts (average number 9.0 ± 2.4) and approximately 8% narrower tertiary ducts (average width 0.65 ± 0.11 mm) compared to the secondary ducts (average width 0.77 ± 0.14 mm). Our anatomical analysis of NAGs in parotid sialo‐CBCT demonstrated progressive narrowing of the main duct and increasing arborization and decreasing lumen size starting from the primary to the tertiary ducts. This is the most updated study regarding the anatomy of the parotid glands as demonstrated in sialo‐CBCT. Our results may provide clinicians with the basic information for understanding aberration from normal morphology, as seen in salivary gland pathologies as well facilitate planning of treatment strategies, such as minimally invasive sialo‐endoscopies, commonly practiced today.

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Bilateral parotid swelling: A review

Cited by 111 publications

References 141 publications

Diagnostic work-up in obstructive and inflammatory salivary gland disorders

Diagnostic work-up in obstructive and inflammatory salivary gland disorders

Idiopathic sialadenosis involving parotid and submandibular glands. A case report.

The anatomical pattern of ductal arborization in parotid glands using cone‐beam computerized sialography

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