SummaryTo investigate the postprocedural cardiovascular events and vascular outcomes, including hand ischemia and neurological compromise, after transulnar (TU) catheterization in ipsilateral radial artery occlusion.Previous randomized trials have shown that the transulnar (TU) approach for coronary angiogram and intervention has safety and outcomes similar to those of the transradial (TR) approach. However, the safety of the TU procedure when ipsilateral radial artery occlusion occurs is unknown.We retrospectively reviewed 87 TU cases with ipsilateral radial artery occlusion confirmed by a forearm angiogram. Eighty percent of these patients had a history of ipsilateral radial artery cannulation or surgery. We avoided the use of over-sized sheaths or applied a sheathless approach during surgery.No ulnar artery occlusion was observed by subsequent Doppler ultrasound or pulse oximetry. No patient developed hand ischemia or serious complications requiring surgery or blood transfusion during the follow-up period of 32.2 ± 24.0 months. Review of the preprocedural forearm angiograms showed that 95.7% of the patients possessed significant collaterals supplying flow from the interosseous artery to the occluded radial artery remnant. Thus, the blood circulation to the palmar arch and digital vessels was maintained even when the ulnar artery was temporarily occluded by an in-dwelling ulnar arterial sheath.TU catheterization was safe in patients with coexisting ipsilateral radial artery occlusions and feasible for use in complex intervention procedures. Cautious manipulation of ulnar artery cannulation and hemostasis helped decrease the risk of hand ischemia. ( and intervention is superior to the transbrachial and transfemoral approaches, with a lower complication rate and better patient tolerance.1,2) Ulnar artery cannulation has anatomical advantages similar to those of radial artery cannulation, such as an easier approach to the wrist portion and better patient compliance for hemostasis. Although there is less anatomical variation and vasospasm in the ulnar artery than in the radial artery, its deeper location and nearby ulnar nerve increases the difficulty of puncture and complication rate.3) To investigate the safety of transulnar (TU) coronary catheterization, limited randomized trials have compared the major adverse cardiovascular (CV) events and major vascular complications between the radial and ulnar artery approaches.4-7) The TU approach has success rates for arterial puncture and coronary intervention similar to those of the TR approach without increasing entry site complications, including arterial occlusion. However, Hahalis, et al have reported not only the relative inferiority of the cross-over rate in the TU access route but also significantly higher puncture trials, longer puncture and fluoroscopy times, and higher amounts of contrast medium in TU patients than in TR patients. 6) Thus, the ulnar artery is recommended as an alternative access site only if the radial arterial approach fails or is not feasib...