Bilateral Synchronous Testicular Involvement in Multiple Myeloma. Case Report and Review of the Literature

Castagna, Maura; Gaeta, P.; Cecchi, M; Pagni, G; Pingitore, Raffaele

doi:10.1177/030089169708300411

Cited by 14 publications

(7 citation statements)

References 17 publications

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“…2 Castagna et al compiled 57 cases with testicular plasmacytoma and only 11 cases had no multiple myeloma for 2 months to 3 years follow-up periods. 3 The present case was thought to be primary testicular plasmacytoma because there was no evidence of multiple myeloma over 9 months' follow-up. Previous reports of testicular plasmacytoma showed that a painless testicular swelling is the most common chief complaint, although hydrocele of the testis as a chief complaint was found in two cases.…”

Section: Discussionmentioning

confidence: 68%

“…Levin and Mostofi examined 6000 testicular and paratesticular tumors and found seven cases with plasmacytoma, in which only one case was thought to be primary testicular plasmacytoma 2 . Castagna et al compiled 57 cases with testicular plasmacytoma and only 11 cases had no multiple myeloma for 2 months to 3 years follow‐up periods 3 . The present case was thought to be primary testicular plasmacytoma because there was no evidence of multiple myeloma over 9 months' follow‐up.…”

Section: Discussionmentioning

confidence: 70%

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Primary testicular plasmacytoma with hydrocele of the testis

et al. 2001

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A case of primary testicular plasmacytoma complicated with hydrocele of the testis is reported. An 86-year-old man presented with hydrocele of the right testis. High inguinal orchiectomy was performed as the preoperative aspiration cytology of the hydrocele fluid showed atypical cells. Immunohistochemical study of the right testis revealed testicular plasmacytoma positive for IgG. He remained well 9 months after the orchiectomy. This is the second reported case where the preoperative diagnosis of testicular plasmacytoma was made based on the hydrocele fluid cytology.

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Section: Discussionmentioning

confidence: 68%

Section: Discussionmentioning

confidence: 70%

Primary testicular plasmacytoma with hydrocele of the testis

et al. 2001

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“…[ 13 23 ] The timeline for this progression can extend as far as several years and as such, these patients need to be closely monitored given the risk of developing subsequent generalized MM. [ 19 23 24 ]…”

Section: Discussionmentioning

confidence: 99%

Plasmacytoma of the testis in a patient with relapsed and refractory multiple myeloma: Case report and review of the literature

et al. 2015

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Testicular plasmacytoma, whether occurring as a primary lesion or as a reflection of underlying multiple myeloma (MM), is a rare disease. We report the case of a 38-year-old male with multiply relapsed MM, who was found to have a testicular plasmacytoma. He presented with a gradually enlarging scrotal mass. Following orchidectomy, pathologic examination of the specimen demonstrated a plasmacytoma. In the context of active MM, the specimen was also sent for cytogenetic analysis but this was unhelpful in guiding a chemotherapy regime, which still continues at time of reporting. Although a rare lesion, there remains no definitive treatment protocol for the management of testicular plasmacytoma representing an extramedullary manifestation of MM.

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“…Such lesions are most commonly found in patients between ages 55 and 60, often with a known diagnosis of multiple myeloma or at the time of known systemic relapse. [8,10,11] Several cases have been reported where these lesions presented in the absence of such history. [3,10] The patient we present here was above average for age and had previously undergone chemotherapy and autologous bone marrow transplantation for treatment of his known myeloma, so the discovery of his bilateral testicular plasmacytomas was thought to be most consistent with disease recurrence.…”

Section: Cellsmentioning

confidence: 99%

Bilateral Testicular Plasmacytomas

Croake

Zhang

et al. 2018

AJS

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Intratesticular masses are common and widely presumed to be malignant until proven otherwise. The most common testicular tumors include germ cell and non-germ cell tumors, typically presenting as solitary, unilateral lesions. Some testicular tumors present with bilateral involvement, the most common of which is Leydig cell hyperplasia, with case reports of other synchronous and metachronous bilateral testicular tumors in the literature. Testicular plasmacytomas in the setting of multiple myeloma have been reported as well but are uncommon. Bilateral testicular plasmacytomas are extremely rare. We present sonographic features, with histopathologic correlation in a 71-year-old man who presented with scrotal pain and was found to have bilateral testicular hypoechoic masses confirmed to be plasmacytomas.

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Bilateral Synchronous Testicular Involvement in Multiple Myeloma. Case Report and Review of the Literature

Cited by 14 publications

References 17 publications

Primary testicular plasmacytoma with hydrocele of the testis

Primary testicular plasmacytoma with hydrocele of the testis

Plasmacytoma of the testis in a patient with relapsed and refractory multiple myeloma: Case report and review of the literature

Bilateral Testicular Plasmacytomas

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