Bilateral vocal fold palsy following COVID-19 infection.

Poutoglidis, Alexandros; Tsetsos, Nikolaos; Karamitsou, Paraskevi; Forozidou, Evropi; Garefis, Konstantinos; Keramari, Stergiani; Vlachtsis, Konstantinos

doi:10.1177/01455613221080987

Cited by 12 publications

(11 citation statements)

References 7 publications

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“…There are very few reports of bilateral recurrent laryngeal nerve palsy during the course of COVID-19 [12,16], with similar findings that paralytic symptoms develop a little later than ventilator withdrawal and do not improve within a short period of time. Previous reports could not ascertain whether the cause of nerve palsy was viral or mechanical in origin; however, in one publication, the authors proved that the recurrent laryngeal nerve did not work using electromyography [17].…”

Section: Discussionmentioning

confidence: 96%

Bilateral Recurrent Laryngeal Nerve Paralysis Manifesting as Long COVID

Okuda¹,

Kunieda²,

Shibata³

et al. 2022

Cureus

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Management with ventilation is used for severe cases of coronavirus disease 2019 . After extubation, recurrent laryngeal nerve paralysis due to various factors may occur. Almost all cases of paralysis develop unilaterally; however, bilateral recurrent laryngeal nerve paralysis occurs rarely. Such cases may be fatal due to upper air obstruction, and patients are forced to adhere to restrictions after a tracheotomy. The present case illustrates bilateral recurrent laryngeal nerve paralysis that occurred 48 hours after withdrawal from the ventilator. A 75-year-old woman with a history of hypertension came to our hospital with a history of fever and cough for five days. She was diagnosed with pneumonia due to COVID-19 via polymerase chain reaction using her saliva, and ground-glass opacity was found in both lung fields on chest X-ray and computed tomography (CT). Mechanical ventilation, steroids, remdesivir, and baricitinib were administered. The patient's fever and oxygenation status improved with these treatments, and she was weaned from the ventilator on the eighth day of hospitalization. She had no symptoms immediately. However, 48 hours after extubation, bilateral recurrent laryngeal nerve paralysis was suspected. Thus, oral intubation was immediately introduced and a tracheostomy was performed. Vocal cord movement disorders continued for eight weeks, and during that period, the patient displayed hoarseness and suffered from dysphagia. We considered that nerve disorders from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in addition to the compression by the endotracheal tube, caused bilateral recurrent laryngeal nerve paralysis. The neural injury by SARS-CoV-2 may prolong and manifest as "Long COVID."

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Section: Discussionmentioning

confidence: 96%

Bilateral Recurrent Laryngeal Nerve Paralysis Manifesting as Long COVID

Okuda¹,

Kunieda²,

Shibata³

et al. 2022

Cureus

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“…From the available literature, it's understood that the main neurological manifestation is in the form of hyposmia, anosmia, and visual disturbances due to the neurotoxic effect of the virus. Poutoglidis et al [ 20 ] reported bilateral vocal fold palsy as a rare neurological manifestation in a post-COVID-19 case who was intubated for a prolonged interval and stayed in the intensive care unit. With prolonged intubation and in the presence of COVID-associated inflammation, the patient had developed cricoarytenoid joint fixation resulting in bilateral vocal fold palsy.…”

Section: Discussionmentioning

confidence: 99%

Preliminary Experience in Post-COVID-19 Mycoses: A Pathologist’s Perspective

Walke¹,

Jayashankar²,

Khurana³

et al. 2022

Cureus

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“…Severe infection with corona virus could result in headache, epilepsy, myasthenia gravis, cranial neuropathies, cerebrovascular events, and encephalitis. 1 , 2 , 3 , 4 , 5 , 6 Coagulopathy is a common feature of the disease, and it is associated with poor prognosis. 7 The association between hyperhomocysteinemia and cerebrovascular disorders have been studied.…”

Section: Introductionmentioning

confidence: 99%

“…Numerous neurological complications of COVID‐19 have been identified. Severe infection with corona virus could result in headache, epilepsy, myasthenia gravis, cranial neuropathies, cerebrovascular events, and encephalitis 1–6 . Coagulopathy is a common feature of the disease, and it is associated with poor prognosis 7 .…”

Section: Introductionmentioning

confidence: 99%