Bimanual Coordination in Chronic Schizophrenia

Bellgrove, Mark A.; Bradshaw, John L.; Velakoulis, Dennis; Johnson, Katherine A.; Rogers, Mark A.; Smith, Deidre J.; Pantelis, Christos

doi:10.1006/brcg.2000.1261

Cited by 16 publications

(6 citation statements)

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“…Finally, 12 S patients were found to fail in a bimanual coordination task, although this impairment may relate to attentional deficits, not necessarily to interhemispheric integration. 128 The results mentioned are compatible with the notion of callosal hypoconnectivity. However, they have the shortcoming of not testing specifically the callosal connections between the prefrontal areas, for which the evidence of decreased connectivity is presently the strongest.…”

Section: Electrophysiological Studiessupporting

confidence: 77%

Schizophrenia, neurodevelopment and corpus callosum

2003

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The Zeitgeist favors an interpretation of schizophrenia as a condition of abnormal connectivity of cortical neurons, particularly in the prefrontal and temporal cortex. The available evidence points to reduced connectivity, a possible consequence of excessive synaptic pruning in development. A decreased thalamic input to the cerebral cortex appears likely, and developmental studies predict that this decrease should entail a secondary loss of both longand short-range cortico-cortical connections, including connections between the hemispheres. Indeed, morphological, electrophysiological and neuropsychological studies over the last two decades suggest that the callosal connections are altered in schizophrenics. However, the alterations are subtle and sometimes inconsistent across studies, and need to be investigated further with new methodologies.

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Section: Electrophysiological Studiessupporting

confidence: 77%

Schizophrenia, neurodevelopment and corpus callosum

2003

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“…Earlier studies used neuropsychological tests to evaluate movements in patients with schizophrenia (Bellgrove et al, 2001;Bilder et al, 2000;Flyckt et al, 1999;Fuller & Jahanshahi, 1999). Their results showed that patients performed slowly or inaccurately on pegboard tests, pronation-supination tests, and out-of-phase bimanual movements.…”

Section: Functional Movements In Patients With Schizophreniamentioning

confidence: 99%

“…Schizophrenia causes complicated and multifaceted impairments and interferes with patients' ability to participate in productive occupations. Studies focused on performance skills have found problems in cognitive skills, social skills, and even motor skills in patients with schizophrenia (Arbesman & Logsdon, 2011;Bellgrove et al, 2001;Carnahan, Elliott, & Velamoor, 1996). Compared with cognitive and social skill problems, motor disorders in patients with schizophrenia have drawn less attention from occupational therapy researchers.…”

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confidence: 99%

Effects of Object Size on Unimanual and Bimanual Movements in Patients With Schizophrenia

Wang

Kuo

Ouyang

et al. 2014

The American Journal of Occupational Therapy

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Schizophrenia affects not only mental function but also movement. We compared the movement of patients with mild schizophrenia and healthy control participants during a bimanual assembly task and examined whether changes in object size affected unimanual and bimanual movements. Fifteen patients with schizophrenia and 15 age- and gender-matched control participants were instructed to bimanually reach for and assemble objects. We manipulated the object size for the left hand (large vs. small) and measured movement time, peak velocity, and bimanual synchronization to represent movement speed, forcefulness, and bimanual coordination. Patients with schizophrenia showed slower and less forceful unimanual movements and less coordinated bimanual movements than control participants. Increasing the object size elicited faster and more forceful unimanual movements and more coordinated bimanual movements in patients. The results suggest the need for movement rehabilitation in patients with schizophrenia and the possibility of manipulating object size to optimize patients' movements. These results benefit the practice of evidence-based therapy.

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“…These tasks involve reaching for and grasping objects (prehension) and then assembling them into a final target (assembly) in a production line. Patients with schizophrenia are reported to have impaired unimanual movements [1][2][3] and impaired bimanual coordination [4] in simple rhythmic tasks; they perform slowly on pegboard tests and pronation-supination tests, and their out-of-phase bimanual movements are inaccurate and unstable [1][2][3][4]. However, movement kinematics (e.g.…”

Section: Introductionmentioning

confidence: 99%