Binaural interactions shape binaural response structures and frequency response functions in primary auditory cortex

Kitzes, L. M.

doi:10.1016/j.heares.2008.01.003

Cited by 10 publications

(7 citation statements)

References 43 publications

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“…These results are consistent with the large population of binaural azimuth-sensitive neurons in AC (Brugge et al, 1994; Harrington et al, 2008; Kitzes, 2008) and with previous studies and views implicating PT in processing of location of sounds in the horizontal plane (Warren and Griffiths, 2003; Barrett and Hall, 2006; Deouell et al, 2007; Rauschecker, 2011). …”

Section: Discussionsupporting

confidence: 90%

Processing of spatial sounds in human auditory cortex during visual, discrimination and 2-back tasks

et al. 2014

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Previous imaging studies on the brain mechanisms of spatial hearing have mainly focused on sounds varying in the horizontal plane. In this study, we compared activations in human auditory cortex (AC) and adjacent inferior parietal lobule (IPL) to sounds varying in horizontal location, distance, or space (i.e., different rooms). In order to investigate both stimulus-dependent and task-dependent activations, these sounds were presented during visual discrimination, auditory discrimination, and auditory 2-back memory tasks. Consistent with previous studies, activations in AC were modulated by the auditory tasks. During both auditory and visual tasks, activations in AC were stronger to sounds varying in horizontal location than along other feature dimensions. However, in IPL, this enhancement was detected only during auditory tasks. Based on these results, we argue that IPL is not primarily involved in stimulus-level spatial analysis but that it may represent such information for more general processing when relevant to an active auditory task.

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Section: Discussionsupporting

confidence: 90%

Processing of spatial sounds in human auditory cortex during visual, discrimination and 2-back tasks

et al. 2014

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“…Now, both ears project upon both auditory forebrains (Phillips and Gates, 1982;Zhang et al, 2004;Kitzes, 2008). Accordingly, even though the gap detection stimulus and the masker were presented to different ears, they each have a representation in both hemispheres, and those representations may interfere or overlap with each other.…”

Section: Effects Of Noise Maskingmentioning

confidence: 99%

“…The perceptual ability to stream or to parse the stimuli presumably depends on the extent to which the representations of the two stimuli are separable in either or both hemispheres. The vast majority of cortical auditory neurons are binaurally influenced and in very diverse ways (Zhang et al, 2004;Kitzes, 2008), and this serves to differentiate the representations of otherwise similar stimuli at different ears very effectively. It is perhaps for this reason that ''ear" is a particularly effective basis for parsing the auditory scene (Boehnke and Phillips, 2005), and it explains why the effect of the interrupted masker in the present study, while statistically significant, was numerically small.…”

Section: Effects Of Noise Maskingmentioning

confidence: 99%

Ear and contralateral masker effects on auditory temporal gap detection thresholds

2008

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“…In the auditory cortex, many neurons respond most strongly to their preferred sound stimuli but less strongly to other nonpreferred sound stimuli. The preferences of cortical neurons to various sound stimulus parameters are often determined by searching their preferred stimuli which evoke the top response strength from their response areas, for example, frequency‐level response area (Recanzone, ; Recanzone, Guard, & Phan, ; Sadagopan & Wang, ), binaural‐level response area (Kitzes, ; Semple & Kitzes, ; Zhang, Nakamoto, & Kitzes, , ), azimuth‐level response area (ALRA) (Barone, Clarey, Irons, & Imig, ; Clarey, Barone, & Imig, ; Eggermont & Mossop, ; Imig, Irons, & Samson, ; Woods, Lopez, Long, Rahman, & Recanzone, ) and spatial response area (Brugge, Reale, & Hind, ; King et al., ; Mrsic‐Flogel, King, & Schnupp, ; Reale, Jenison, & Brugge, ). Whereas most of these previous studies were documented in quiet conditions, only a few studies focused on investigating the tuning of cortical neurons to auditory stimuli in noisy conditions.…”

Section: Introductionmentioning

confidence: 99%

Nonuniform impacts of forward suppression on neural responses to preferred stimuli and nonpreferred stimuli in the rat auditory cortex

Gao

Chen

Zhang

2018

Eur J of Neuroscience

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In natural conditions, human and animals need to extract target sound information from noisy acoustic environments for communication and survival. However, how the contextual environmental sounds impact the tuning of central auditory neurons to target sound source azimuth over a wide range of sound levels is not fully understood. Here, we determined the azimuth-level response areas (ALRAs) of rat auditory cortex neurons by recording their responses to probe tones varying with levels and sound source azimuths under both quiet (probe alone) and forward masking conditions (preceding noise + probe). In quiet, cortical neurons responded stronger to their preferred stimuli than to their nonpreferred stimuli. In forward masking conditions, an effective preceding noise reduced the extents of the ALRAs and suppressed the neural responses across the ALRAs by decreasing the response strength and lengthening the first-spike latency. The forward suppressive effect on neural response strength was increased with increasing masker level and decreased with prolonging the time interval between masker and probe. For a portion of cortical neurons studied, the effects of forward suppression on the response strength to preferred stimuli was weaker than those to nonpreferred stimuli, and the recovery from forward suppression of the response strength to preferred stimuli was earlier than that to nonpreferred stimuli. We suggest that this nonuniform forward suppression of neural responses to preferred stimuli and to nonpreferred stimuli is important for cortical neurons to maintain their relative stable preferences for target sound source azimuth and level in noisy acoustic environments.

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Binaural interactions shape binaural response structures and frequency response functions in primary auditory cortex

Cited by 10 publications

References 43 publications

Processing of spatial sounds in human auditory cortex during visual, discrimination and 2-back tasks

Processing of spatial sounds in human auditory cortex during visual, discrimination and 2-back tasks

Ear and contralateral masker effects on auditory temporal gap detection thresholds

Nonuniform impacts of forward suppression on neural responses to preferred stimuli and nonpreferred stimuli in the rat auditory cortex

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