Bio-Alcamid, a Novel Prosthetic Polymer, Does Not Interfere With Morphological and Functional Characteristics of Human Skin Fibroblasts

Pacini, Stefania; Ruggiero, Marco; Cammarota, N.; Protopapa, Carmelo; Gulisano, Massimo

doi:10.1097/00006534-200301000-00092

Cited by 39 publications

(25 citation statements)

References 7 publications

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“…Because polyalkylimide is not derived from animals, and no heterologous protein has been added to it, allergy tests have not been recommended. 8,9 It is frequently characterized as a "semipermanent" filler because, theoretically, the implants will not be reabsorbed and can be removed in cases of overfilling or adverse reactions. 8 Polyalkylimide is used to treat diverse aesthetic facial defects, especially in the lips, cheeks, glabella, and nasolabial folds.…”

Section: Commentmentioning

confidence: 99%

See 1 more Smart Citation

Delayed Immune-Mediated Adverse Effects of Polyalkylimide Dermal Fillers

Alijotas‐Reig

Garcia-Gimenez²,

Miró-Mur³

et al. 2008

Arch Dermatol

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Section: Commentmentioning

confidence: 99%

“…In the early reports on PAI injections for cosmetic purposes, there were no significant signs of bioincompatibility. [9][10][11][12][13] However, more recent evidence refutes these statements, and so the complete safety of PAI gels can no longer be assured. 1,7,14,15 We describe a cohort of patients with delayed adverse reactions to PAI fillers.…”

mentioning

confidence: 99%

Delayed Immune-Mediated Adverse Effects of Polyalkylimide Dermal Fillers

Alijotas‐Reig

Garcia-Gimenez²,

Miró-Mur³

et al. 2008

Arch Dermatol

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Section: Introductionmentioning

confidence: 99%

“…It contains 96% water and 4% alkylinide-amide groups [17]. In their study, Pacini et al [17] found that Bio-Alcamid was totally biocompatible with cell proliferation, and the filler does not integrate into the surrounding tissue. After injection, a thin membrane is created by the body around the material [18] which then acts as an endoprosthesis.…”

Section: Introductionmentioning

confidence: 99%

Preliminary Experiences with Bio-Alcamid in HIV Facial Lipoatrophy

2007

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Background: Highly active antiretroviral therapy for HIV-infected patients causes metabolic changes known as the lipodystrophy syndrome. Autologous fat injections, dermal fat grafts, malar implants and injected fillers have been reported as treatment options. Objective: To evaluate the results of HIV-infected patients treated with Bio-Alcamid for facial lipoatrophy. Methods and Materials: Over a 3-year period, 13 HIV-infected patients with facial lipoatrophy had Bio-Alcamid injections for aesthetic purposes. The procedure was done under local anesthesia, and the amount of the injected material varied from 5 to 13 ml. Results were independently evaluated by patients and physicians. Results: Most of the patients felt they had good to excellent results. Touch-ups were necessary for 2 patients; the added volume was 2–3 ml for each. No major complications were recorded. A small hematoma was noted in 1 patient. Overcorrection was attained in 2 cases, and some of the filler was removed at the patient’s request. Conclusion: One of the greatest advantages of this filler is that, although permanent, it can be removed easily. We consider Bio-Alcamid to be a safe and useful correcting tool for patients suffering from drug-induced facial lipoatrophy.

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“…Desde mediados de los años noventa, los cirujanos que realizamos procedimientos quirúrgicos reconstructivos y estéticos, disponemos de materiales inyectables biocompatibles, 9 que permiten otorgar relleno y/o volumen a regiones tan dispares como la cara o las mamas. A nivel facial, estos materiales se utilizan tanto en la cirugía reconstructiva (para relleno de defectos creados tras exé-resis oncológicas o defectos postraumáticos), como en la estética (para relleno de labios, con el fin de aumentar la proyección de los mismos; surcos, etc.…”

Section: Introductionunclassified

Utilización de polialcamida en cirugía reconstructiva y estética facial

Gil

Carrasco

Ruiz

et al. 2007

Rev Esp Cirug Oral y Maxilofac

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Resumen: Objetivos. Presentar nuestra experiencia en el manejo y aplicación de biomateriales no reabsorbibles (poliaquilamida) en pacientes con defectos faciales de diversa etiología. Material y métodos. Empleamos poliaquilamida (Bio-Alcamid ® ) en un total de catorce pacientes. Cuatro pacientes presentaban distintos grados de lipodistrofia facial secundaria a tratamientos antiretrovirales. Otros cuatro, consultaron porque deseaban mejorar el aspecto de su perfil labial. Tres pacientes habían sido sometidos con anterioridad a exéresis oncológicas, y otros dos mostraban defectos faciales derivados de traumatismos. Finalmente, un paciente presentaba un defecto nasal, secuela de una rinoplastia previa. Resultados. Todos los pacientes mostraron un índice muy elevado de satisfacción. No se registraron complicaciones graves. Queremos señalar la estabilidad y durabilidad del implante. Conclusiones. La seguridad y sencillez de esta técnica asociada al alto grado de satisfacción manifestado por los pacientes, animan al empleo de estas sustancias en la corrección de defectos faciales de diversa etiología.

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Bio-Alcamid, a Novel Prosthetic Polymer, Does Not Interfere With Morphological and Functional Characteristics of Human Skin Fibroblasts

Cited by 39 publications

References 7 publications

Delayed Immune-Mediated Adverse Effects of Polyalkylimide Dermal Fillers

Delayed Immune-Mediated Adverse Effects of Polyalkylimide Dermal Fillers

Preliminary Experiences with Bio-Alcamid in HIV Facial Lipoatrophy

Utilización de polialcamida en cirugía reconstructiva y estética facial

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