Bio-based elastomer nanoparticles with controllable biodegradability

Wang, Qingguo; Zai, Yingying; Yang, Dejing; Qiu, Liyan; Niu, Chengqun

doi:10.1039/c6ra24336c

Cited by 10 publications

(8 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, neat PLA has a low degradation rate in soil. However, the PLA/BEP composites presented a better degradability than neat PLA, which indicates that BEP exhibit good degradability and produce some low-molecular-weight aliphatic acids and aliphatic alcohols in the degradation process [35]. Thereby, the presence of BEP in the PLA matrix increase the degradation rates of the PLA/BEP composites.…”

Section: Resultsmentioning

confidence: 99%

“…In our previous work, using some bio-based monomers, such as propanediol, butanediol, succinic acid, sebacic acid, itaconic acid, and fumaric acid, we successfully fabricated novel biodegradable elastomer particles (BEP) by technologies based on melt polycondensation of aliphatic unsaturated polyester, polyester emulsified, and electron beam irradiation vulcanization [35]. It is worth noting that micro-nanoscale BEP are biodegradable due to the ester group in the macromolecular chains of the aliphatic polyester.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Toughened Poly(lactic acid)/BEP Composites with Good Biodegradability and Cytocompatibility

Wang

Zhou

et al. 2019

Polymers

Self Cite

View full text Add to dashboard Cite

Using novel biodegradable elastomer particles (BEP) prepared by the technologies of melt polycondensation, emulsification, and irradiation vulcanization, we successfully prepared advanced poly(lactic acid) (PLA)/BEP composites with higher toughness, higher biodegradability, and better cytocompatibility than neat PLA by means of the melt blending technology. The experimental results revealed that the elongation at break of the PLA/BEP composites containing 8 parts per hundred rubber (phr) by weight BEP increased dramatically from 2.9% of neat PLA to 67.1%, and the notched impact strength increased from 3.01 to 7.24 kJ/m2. Meanwhile, the biodegradation rate of the PLA/BEP composites increased dramatically in both soil environment and lipase solution, and the crystallization rate and crystallinity of the PLA/BEP composites increased significantly compared to those of neat PLA. The methyl thiazolyl tetrazolium (MTT) assay also showed that the viability of L929 cells in the presence of extracts of PLA/BEP composites was more than 75%, indicating that the PLA/BEP composites were not cytotoxic and had better cytocompatibility than neat PLA. Research on advanced PLA/BEP composites opens up new potential avenues for preparing advanced PLA products, especially for advanced biomedical materials.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Toughened Poly(lactic acid)/BEP Composites with Good Biodegradability and Cytocompatibility

Wang

Zhou

et al. 2019

Polymers

Self Cite

View full text Add to dashboard Cite

show abstract

“…The lipase degradation method was as follows [35,36]. Approximately 0.5 g of the dried BTPU sample, weighed as W 0 , was placed into a tube.…”

Section: Methodsmentioning

confidence: 99%

Fabrication and Properties of a Bio-Based Biodegradable Thermoplastic Polyurethane Elastomer

et al. 2019

Self Cite

View full text Add to dashboard Cite

Using the melt polycondensation of five bio-based aliphatic monomers (succinic acid, sebacic acid, fumaric acid, 1,3-propanediol, and 1,4-butanediol), we first synthesized the more flexible and biodegradable polyester diols (BPD) with an average molecular weight of 3825. Then, the BPD was polymerized with excessive 4,4′-diphenylmethane diisocyanate (MDI). Finally, the molecular chain extender of 1,4-butanediol (BDO) was used to fabricate the biodegradable thermoplastic polyurethane elastomer (BTPU), comprising the soft segment of BPD and the hard segment polymerized by MDI and BDO. Atomic force microscope (AFM) images showed the two-phase structure of the BTPU. The tensile strength of the BTPU containing 60% BPD was about 30 MPa and elongation at break of the BTPU was over 800%. Notably, the BTPU had superior biodegradability in lipase solution and the biodegradation weight loss ratio of the BTPU containing 80% BPD reached 36.7% within 14 days in the lipase solution.

show abstract

“…In-situ cross-linked polyester elastomers are usually used in biomedical applications due to their excellent biocompatibility and nonbiotoxicity. [155][156][157][158][159] The first chemically cross-linkable elastomer is developed in 2008 by Liqun Zhang. 160 Subsequently, more novel bio-based polyester engineering elastomers are developed for many potential applications.…”

Section: Bio-based Polyester Elastomersmentioning

confidence: 99%

“…They have tunable degradability and adequate flexibility. 155,157,159,165 Citrate-based elastomers (CBEs) are common to biomedical applications. Since α-and β-carboxyl groups have different reactivities, the degree of cross-linking, mechanical properties, and degradability of CBEs can be adjusted by changing the molar ratio and the kinetics of reaction between citric acid (CA) and diols.…”

Section: Bio-based Polyester Elastomersmentioning

confidence: 99%

Current trends in bio‐based elastomer materials

Tang

Wang

et al. 2022

SusMat

View full text Add to dashboard Cite

Elastomers play an irreplaceable role in our society due to their unique properties. Natural rubber is directly obtained from plants and is widely used in tires, shoes, etc. Recently, modified natural rubbers are proposed to expand the application of natural rubber. However, these natural rubbers have a limited variety of molecular structures and may not be able to meet ever-demanding applications. Traditional synthetic elastomers have a variety of molecular structures and their properties are used in various fields, but mainly originate from fossil resources. This review deals with bio-based elastomers, and more specifically natural rubber and bio-based synthetic elastomers. Based on reprocessability, bio-based elastomers can also be divided into bio-based chemically cross-linked ones and thermoplastic ones. Compared to traditional fossil-based elastomers, bio-based ones may alleviate environmental pollution and promote the sustainable development of the elastomer industry. K E Y W O R D Sbio-based elastomers, chemically cross-linked, natural rubber, synthetic rubber INTRODUCTIONElastomers are polymeric materials possessing low modulus and high elasticity, and can rapidly recover their orig-This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

show abstract

Bio-based elastomer nanoparticles with controllable biodegradability

Abstract: Using melt polycondensation of bio-derived dicarboxylic acids and diols, followed by polyester emulsification and radiation, we fabricate the bio-based elastomer nanoparticles with controllable biodegradability, which can be used in biomedical fields.

Cited by 10 publications

References 30 publications

Toughened Poly(lactic acid)/BEP Composites with Good Biodegradability and Cytocompatibility

Toughened Poly(lactic acid)/BEP Composites with Good Biodegradability and Cytocompatibility

Fabrication and Properties of a Bio-Based Biodegradable Thermoplastic Polyurethane Elastomer

Current trends in bio‐based elastomer materials

Contact Info

Product

Resources

About