Bio-MEMS based sensor for acute and chronic pain management: An online measurement strategy for using biomedicai MEMS sensor in the assessment of pain intensity and study of inflammation

Sathiyabama, G.; Krishnan, S. Sankara; Saravanan, D.; Kumaran, Rajiv

doi:10.1109/ncetnresem.2014.7088772

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…In [268], a biosensor was proposed for the evaluation of pain intensity based on the detection of inflammation markers such as Prostaglandine E2, Cyclooxygenase (COX − 1 and COX − 2), Leucotrien (LTA 4 and LTB 4 ) and Troponin-C. These measurements are routinely performed in blood analysis laboratories, using specialized equipment based on enzyme-linked immunosorbent assay (ELISA).…”

Section: Other Pain Sensors and Data Fusionmentioning

confidence: 99%

Sensor Technologies to Manage the Physiological Traits of Chronic Pain: A Review

Naranjo-Hernández

Reina‐Tosina

Roa

2020

Sensors

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Non-oncologic chronic pain is a common high-morbidity impairment worldwide and acknowledged as a condition with significant incidence on quality of life. Pain intensity is largely perceived as a subjective experience, what makes challenging its objective measurement. However, the physiological traces of pain make possible its correlation with vital signs, such as heart rate variability, skin conductance, electromyogram, etc., or health performance metrics derived from daily activity monitoring or facial expressions, which can be acquired with diverse sensor technologies and multisensory approaches. As the assessment and management of pain are essential issues for a wide range of clinical disorders and treatments, this paper reviews different sensor-based approaches applied to the objective evaluation of non-oncological chronic pain. The space of available technologies and resources aimed at pain assessment represent a diversified set of alternatives that can be exploited to address the multidimensional nature of pain.

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Section: Other Pain Sensors and Data Fusionmentioning

confidence: 99%

Sensor Technologies to Manage the Physiological Traits of Chronic Pain: A Review

Naranjo-Hernández

Reina‐Tosina

Roa

2020

Sensors

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Anti-Biofouling Strategies for Long-Term Continuous Use of Implantable Biosensors

Lee

2020

Chemosensors

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The growing trend for personalized medicine calls for more reliable implantable biosensors that are capable of continuously monitoring target analytes for extended periods (i.e., >30 d). While promising biosensors for various applications are constantly being developed in the laboratories across the world, many struggle to maintain reliable functionality in complex in vivo environments over time. In this review, we explore the impact of various biotic and abiotic failure modes on the reliability of implantable biosensors. We discuss various design considerations for the development of chronically reliable implantable biosensors with a specific focus on strategies to combat biofouling, which is a fundamental challenge for many implantable devices. Briefly, we introduce the process of the foreign body response and compare the in vitro and the in vivo performances of state-of-the-art implantable biosensors. We then discuss the latest development in material science to minimize and delay biofouling including the usage of various hydrophilic, biomimetic, drug-eluting, zwitterionic, and other smart polymer materials. We also explore a number of active anti-biofouling approaches including stimuli-responsive materials and mechanical actuation. Finally, we conclude this topical review with a discussion on future research opportunities towards more reliable implantable biosensors.

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Bio-MEMS based sensor for acute and chronic pain management: An online measurement strategy for using biomedicai MEMS sensor in the assessment of pain intensity and study of inflammation

Abstract: brought recently. The table below shows the applications used so far by the implementation ofBIO-MEMS based sensors.

Cited by 2 publications

References 9 publications

Sensor Technologies to Manage the Physiological Traits of Chronic Pain: A Review

Sensor Technologies to Manage the Physiological Traits of Chronic Pain: A Review

Anti-Biofouling Strategies for Long-Term Continuous Use of Implantable Biosensors

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