Bio‐orthogonal “Double‐Click” Chemistry Based on Multifunctional Coatings

Peptide-Functionalized Oxime Hydrogels with Tunable Mechanical Properties and Gelation Behavior

“…An additional protein binding experiment was conducted with tetramethylrhodamine-5(6)-isothiocyanate (TRITC) labeled streptavidin. 71, 72 The strong red fluorescence of labeled streptavadin protein confirms the existence and bioavailability of biotin in the hydrogels (Figure 6(b2). The dark region is the glass slide background.…”

Towards a biocompatible artificial lung: Covalent functionalization of poly(4-methylpent-1-ene) (TPX) with cRGD pentapeptide

“…The importance of developing strategies for this kind of copper-free surface functionalization reported here was recently also demonstrated by the Lahann group [35]. We believe that the copper-free approach described is of general importance and should be transferrable to (bio)polymers, inorganic materials or to metals such as titanium used in biomedical devices [36].…”

Hierarchically Functionalized Magnetic Core/Multishell Particles and Their Postsynthetic Conversion to Polymer Capsules

“…13 These surface-grafted gels combine the advantages of MOF materials (highly organized molecular building blocks with various functional groups 14,15 and enormous variability in network topologies 16 ) with that of polymer hydro-gels (pronounced stability against water and the absence of metal ions). 17 The SURGEL 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 3 substrates showed high potential as cell culture substrate 10 as well as for electrochemical applications. 18 The ability to grow MOF shells around magnetic core particles 19 can be combined with the SURGEL approach to developed a kind of "tool box" to create highly versatile capsules containing different "loadings".…”