Bioaccessibility of polychlorinated biphenyls in different foods using an in vitro digestion method

‘Towards a unified approach for the determination of the bioaccessibility of organic pollutants’

“…The bioaccessibility of PAHs from fish was much greater c. 30-70% again declining with increasing K OW (Wang et al, 2010), this high bioaccessibility was recorded despite a very low concentration of bile salts (0.003 g mL −1 ). Experiments with different fish species such as oriental weather fish and bighead carp concluded that high lipid content of fish resulted in lower bioaccessibility results as lipids are not water soluble (Xing et al, 2008). This finding is contradicted by Yu et al (2011) who reported that bioaccessibility of PBDEs in fish increased with increasing fat content of the matrix, the bioaccessibility range was 5.2-105.3 for ΣPBDEs.…”

“…They employed a bioaccessibility test with a gastric and intestinal phase with a high loading of bile salts in the latter (5 g L − 1 ). Xing et al (2008) also recorded low bioaccessibilities of PCBs in fish 1-9% using a two compartment model, but with a lower loading of bile salts (1.5 mg mL −1 ), bioaccessibility was correlated with water solubility, MW, K OW and K OA (r 2 = 0.46, 0.68, 0.67, 0.68 respectively). The bioaccessibility of PAHs from fish was much greater c. 30-70% again declining with increasing K OW (Wang et al, 2010), this high bioaccessibility was recorded despite a very low concentration of bile salts (0.003 g mL −1 ).…”

Novel approaches to improving the chemical safety of the meat chain towards toxicants

“…Values of bioaccessibility found in the literature vary considerably depending on contaminants, even for congeners of the same family (Amiard et al, 2008;Xing et al, 2008). For example, for PCBs, bioaccessibility ranges depending on chlorination, the least chlorinated PCBs being the most bioaccessible (Xing et al, 2008). Xing et al (2008) found an average bioaccessibility of 3% in animal products with one of the highest values (6%) obtained for PCB 28 with 3 chlorine atoms.…”

“…For example, for PCBs, bioaccessibility ranges depending on chlorination, the least chlorinated PCBs being the most bioaccessible (Xing et al, 2008). Xing et al (2008) found an average bioaccessibility of 3% in animal products with one of the highest values (6%) obtained for PCB 28 with 3 chlorine atoms. For PBDEs in beef, the bioaccessibility varies from 16.5% for BDE 17 to 24% for BDE 138.…”

“…They concern PCBs (Xing, Yang, Chan, Tao, & Wong, 2008), brominated flame retardants (Yu et al, 2010(Yu et al, , 2011, pesticides (Yu et al, 2012), heavy metals (Gao & Wang, 2014), and heterocyclic aromatic amines (Kulp, Fortson, Knize, & Felton, 2003). Values of bioaccessibility found in the literature vary considerably depending on contaminants, even for congeners of the same family (Amiard et al, 2008;Xing et al, 2008).…”