Bioaccumulation and toxicokinetics of zinc oxide nanoparticles (ZnO NPs) co-exposed with graphene nanosheets (GNs) in the blackfish (Capoeta fusca)

Sayadi, Mohammad Hossein; Pavlaki, Maria D.; Freitas, Rosa; Mansouri, Borhan; Tyler, Charles R.; Kharkan, Javad; Shekari, Hossein

doi:10.1016/j.chemosphere.2020.128689

Cited by 35 publications

(14 citation statements)

References 50 publications

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“…The detection of Zn residues in the female’s body agrees with a previous work that found the accumulation of Zn resulting from waterborne exposure to ZnO-NPs to be 7 to 12 times higher in blackfish than in the control group [ 53 ]. Kaya, et al found that 14 days of waterborne exposure by Oreochromis niloticus to small (30 nm) and large (100 nm) ZnO-NPs led to a significant accumulation of ZnO-NPs in the tissues [ 54 ].…”

Section: Discussionsupporting

confidence: 89%

Zinc Oxide Nanoparticles (ZnO-NPs) Suppress Fertility by Activating Autophagy, Apoptosis, and Oxidative Stress in the Developing Oocytes of Female Zebrafish

et al. 2022

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In vertebrates, the core mechanisms that control gametogenesis are largely multiple, complex, successive, and orchestrated by intrinsic and extrinsic factors. However, age, health status, and hormonal activity are important factors for good fertility; other intangible intracellular molecular mechanisms that manage oocyte development are still unclear. The present study was designed to elucidate the ultrastructure changes in the ovary in response to its exposure to zinc oxide nanoparticles (ZnO-NPs) and to explore the role of autophagy and apoptosis during egg maturation and ovulation on the fertility of female zebrafish. In our study, ZnO-NPs could induce cytotoxicity in the maturing oocyte by activating autophagy and apoptosis in a caspase-dependent manner and could induce oxidative stress by generating reactive oxygen species (ROS) that elevated the mutated ovarian tP53 protein. Simultaneously, necroptosis developed, mimicking the features of apoptosis and necrosis. Collectively, ZnO-NPs created a suitable necrotic environment that led to follicular developmental retardation that altered oocyte ovulation and reduced fecundity of female zebrafish.

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Section: Discussionsupporting

confidence: 89%

Zinc Oxide Nanoparticles (ZnO-NPs) Suppress Fertility by Activating Autophagy, Apoptosis, and Oxidative Stress in the Developing Oocytes of Female Zebrafish

et al. 2022

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“…Zhao et al explained the reduced exposure of alga to GO in the presence of nAl 2 O 3 due to GO-nAl 2 O 3 heteroaggregation. Evidently, the proposed reason for the attenuation effect is related to coaggregation and surface complexation, a reduction in the bioavailability of toxic components, , and oxidative stress symptoms. , In addition, such potentiation or attenuation of effects is relative if the mixture effect lies between the effects of the individual ENPs …”

Section: Resultsmentioning

confidence: 99%

Review and Prospects on the Ecotoxicity of Mixtures of Nanoparticles and Hybrid Nanomaterials

Zhang

Wang

Peijnenburg

et al. 2022

Environ. Sci. Technol.

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The rapid development of nanomaterials (NMs) and the emergence of new multicomponent NMs will inevitably lead to simultaneous exposure of organisms to multiple engineered nanoparticles (ENPs) at varying exposure levels. Understanding the joint impacts of multiple ENPs and predicting the toxicity of mixtures of ENPs are therefore evidently of importance. We reviewed the toxicity of mixtures of ENPs to a variety of different species, covering algae, bacteria, daphnia, fish, fungi, insects, and plants. Most studies used the independent-action (IA)-based model to assess the type of joint effects. Using co-occurrence networks, it was revealed that 53% of the cases with specific joint response showed antagonistic, 25% synergistic, and 22% additive effects. The combination of nCuO and nZnO exhibited the strongest interactions in each type of joint interaction. Compared with other species, plants exposed to multiple ENPs were more likely to experience antagonistic effects. The main factors influencing the joint response type of the mixtures were (1) the chemical composition of individual components in mixtures, (2) the stability of suspensions of mixed ENPs, (3) the type and trophic level of the individual organisms tested, (4) the biological level of organization (population, communities, ecosystems), (5) the exposure concentrations and time, (6) the endpoint of toxicity, and (7) the abiotic field conditions (e.g., pH, ionic strength, natural organic matter). This knowledge is critical in developing efficient strategies for the assessment of the hazards induced by combined exposure to multiple ENPs in complex environments. In addition, this knowledge of the joint effects of multiple ENPs assists in the effective prediction of hybrid NMs.

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“…A recent study demonstrated that co-exposure of ZnO-NPs with GNs decreased the accumulation of Zn. The accumulation and removal of Zn from ZnO-NPs in blackfish (Capoeta fusca) is dependent on tissue, exposure concentration, and time, as well as graphene nanosheets (GN) [111]. Furthermore, chemically synthetized ZnO-NPs have been recognized as the strongest photocatalysts [112].…”

Section: Imaging Agentsmentioning

confidence: 99%

Biological and Non-Conventional Synthesis of Zinc Oxide Nanoparticles (ZnO-NPs): Their Potential Applications

2022

J Nanotechnol Nanomaterials

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Zinc oxide nanoparticles (ZnO-NPs) are odorless, white, and insoluble in water and alcohol. There are various applications for ZnO due to its unique semiconducting, piezoelectric, and optical features. Biodegradability and low toxicity are important properties of ZnO nonmaterial. The OH groups on the ZnO surface allow different surface decorating molecules to easily functionalize it. Mineralized in muscle, brain, skin, bone, and other tissues, zinc is a necessary mineral. It is a major component of most enzyme systems and is involved in protein and macromolecule production, neurogenesis, and hematopoiesis, among other functions. Due to its small particle size, Nano-ZnO is easily absorbed by the body. So-called nano-ZnO is commonly utilized in food additives. Chemical surface properties, particle shape, size distribution, and particle reactivity in solution all influence the biological activity of nanoparticles. Determining the morphology, size, and functioning of nanoparticles with regulated structures is critical for biological applications. In this review article, biological and non-conventional synthesis and applications of ZnO-NPs are highlighted in terms of their biological activity. ZnO-NPs have shown therapeutic activity against cancer, diabetes, microbial infection, inflammation, and potential antioxidant activity, which can be used as drug carriers, imaging tools, and biosensors.

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Bioaccumulation and toxicokinetics of zinc oxide nanoparticles (ZnO NPs) co-exposed with graphene nanosheets (GNs) in the blackfish (Capoeta fusca)

Cited by 35 publications

References 50 publications

Zinc Oxide Nanoparticles (ZnO-NPs) Suppress Fertility by Activating Autophagy, Apoptosis, and Oxidative Stress in the Developing Oocytes of Female Zebrafish

Zinc Oxide Nanoparticles (ZnO-NPs) Suppress Fertility by Activating Autophagy, Apoptosis, and Oxidative Stress in the Developing Oocytes of Female Zebrafish

Review and Prospects on the Ecotoxicity of Mixtures of Nanoparticles and Hybrid Nanomaterials

Biological and Non-Conventional Synthesis of Zinc Oxide Nanoparticles (ZnO-NPs): Their Potential Applications

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