Bioactive and degradable organic–inorganic hybrids

Martín, Ana Isabel Morales; Salinas, Antonio J.; Vallet‐Regí, María

doi:10.1016/j.jeurceramsoc.2004.09.030

Cited by 45 publications

(32 citation statements)

References 13 publications

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“…XRD analyses were conducted in the 2θ range from 3.03 to 89.91 • with steps of 0.06 • . Narrow peaks identified within the scan range were confirmed using previously published literature [30,31,34,45,46]. …”

Section: Crystallinity and Phase Characterization By X-ray Diffractionsupporting

confidence: 67%

Nanostructured poly(vinyl alcohol)/bioactive glass and poly(vinyl alcohol)/chitosan/bioactive glass hybrid scaffolds for biomedical applications

Mansur

Costa

2008

Chemical Engineering Journal

181

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Section: Crystallinity and Phase Characterization By X-ray Diffractionsupporting

confidence: 67%

Nanostructured poly(vinyl alcohol)/bioactive glass and poly(vinyl alcohol)/chitosan/bioactive glass hybrid scaffolds for biomedical applications

Mansur

Costa

2008

Chemical Engineering Journal

181

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“…3), materials can be shaped into different forms depending on the processing techniques used to fabricate scaffolds (foaming [17,18], sintering [19], salt leaching [20], rapid-prototyping [21], electrospinning [22], etc). Each technique results in materials with specific pore size and interconnectivity, which can be controlled by varying the experimental parameters [23].…”

Section: Scaffold Architecturementioning

confidence: 99%

“…Examples of hybrid scaffolds prepared using different process techniques (from left to right): foams, monoliths, fibers. (picture a is adapted from [17] and from [18] with permissions, picture b from [19] with permission, picture c from the author's own propriety).…”

Section: Scaffold Architecturementioning

confidence: 99%

“…If the nature of the precursors is not properly considered, and if the conditions of the hydrolysis reaction are not well controlled, the crosslinking and phase interpenetration may not be sufficient to tailor the degradation of the material efficiently. In the case of a fast degradation might not be suitable to support bioactivity, for example [19]. Another drawback for the production of these materials is the phase separation that might occur due to incompatibilities be-tween the phases.…”

Section: Hybrids Class Imentioning

confidence: 99%

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Hybrid Organic-Inorganic Scaffolding Biomaterials for Regenerative Therapies

Sachot¹,

Engel²,

Castaño

2014

COC

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Abstract:The introduction of hybrid materials in regenerative medicine has solved some problems related to the mechanical and bioactive properties of biomaterials. Calcium phosphates and their derivatives have provided the basis for inorganic components, thanks to their good bioactivity, especially in bone regeneration. When mixed with biodegradable polymers, the result is a synergic association that mimics the composition of many tissues of the human body and, additionally, exhibits suitable mechanical properties. Together with the development of nanotechnology and new synthesis methods, hybrids offer a promising option for the development of a third or fourth generation of smart biomaterials and scaffolds to guide the regeneration of natural tissues, with an optimum efficiency/cost ratio. Their potential bioactivity, as well as other valuable features of hybrids, open promising new pathways for their usein bone regeneration and other tissue repair therapies. This review provides a comprehensive overview of the different hybrid organic-inorganic scaffolding bio-materials developed so far for regenerative therapies, especially in bone. It also looks at the potential for research into hybrid materials for other, softer tissues, which is still at an initial stage, but with very promising results.

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“…Martín et al have also reported on this system obtained as monoliths and characterized before and after being soaked in simulated body fluid (SBF) [62,63]. The biodegradability and bioactivity of the hybrids were studied as a function of the PVAL content.…”

Section: Bg-poly(vinyl Alcohol)mentioning

confidence: 99%