Bioactive Compounds and Antioxidant, Antiperoxidative, and Antihemolytic Properties Investigation of Three Apiaceae Species Grown in the Southeast of Morocco

Abstract

For a long time, Apiaceae species have been widely employed in the southeast of Morocco for culinary and folk healing purposes. In the current study, we investigated three Apiaceae herbs known as coriander (Coriandrum sativum), celery (Apium graveolens), and parsley (Petroselinum crispum) for their antioxidant, antiperoxidative, and antihemolytic properties. The HPLC-DAD has been used to classify and measure phenolic compounds. The major phenolic compounds studied were p-coumaric, chlorogenic, caffeic acids, luteolin, and quercetin. The polyphenol level was also estimated via Folin–Ciocalteu’s method, aluminium chloride, and acidified vanillin. Parsley showed the highest polyphenol level and, thus, showed potential antioxidant activities demonstrated by DPPH, ABTS scavenging tests, and reducing power (FRAP), as well as TBARS assays. Very strong correlations were depicted among phenol levels and antioxidant assays (R2 ≥ 0.910) and among antihemolytic activity and flavonoids (R2 ≥ 0.927), indicating the implication of phenolic compounds, mainly flavonoids, in the antiradical properties. These finding may prove the traditional use of these Apiaceae species in the management of numerous disorders cited within the Moroccan pharmacopoeia.

Plant Resources Utilization among Different Ethnic Groups of Ladakh in Trans-Himalayan Region

“…The large number of therapeutic plants from the families Asteraceae, Apiaceae, Fabaceae, Lamiaceae, Ranunculaceae, and Polygonaceae is possibly due to the abundance and wider distribution of these families in this area [ 43 ]. Furthermore, according to various researchers [ 49 , 50 , 51 ], the members of these families have a high content of useful bioactive compounds.…”

Bioactive Properties and Phenolic Compound Profiles of Turnip-Rooted, Plain-Leafed and Curly-Leafed Parsley Cultivars

“…Moreover, Chaves et al [29] also identified flavonoids such as apigenin, cosmosiin, apiin and coumarin as the major compounds detected in aqueous extracts of plain-leafed parsley leaves. By contrast, Nour et al [30] suggested myricetin and quercetin as the major phenolic compounds in parsley leaves, and they also detected several phenolic acids in considerable amounts (salicylic, sinapic, ferulic and ellagic acid), whereas Justesen and Knuthsen [31] detected apigenin, quercetin and luteolin. According to Mazzucotelli et al [32], catechin was the most abundant free phenolic compound, whereas p-cumaric acid and rutin were identified as bound polyphenols.…”

In vitro investigation of antioxidant and antihemolytic activities of three Lamiaceae species from Morocco

“…Our results are also in the same line with previous investigations that have proven the remarkable antihemolytic activity of several plant extracts, and the capacity of the phenolic content to protect erythrocytes from oxidative stress or to increase their resistance to oxidativeinduced damage. Indeed, in a recent scientific work, Deruich et al [44] assessed the protective effect of erythrocyte membrane against AAPH-induced hemolysis of three Apiaceae plants from Morocco and, thus, they concluded that Petroselinum crispum manifested the highest protective effect (HT 50% = 273.64 min) and Apium graveolens recorded the lowest effect (HT 50% = 194.71 min). Moreover, Bhat and his collaborators [45] displayed that an alcoholic extract of Caralluma quadrangula from the Northwestern region of Saudi Arabia exhibited an inhibition of red blood cell lysis close to 90% at the highest concentration 2000 μg/mL.…”