Synthesis of Medicinal Agents From Plants 2018
DOI: 10.1016/b978-0-08-102071-5.00004-0
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Bioactive constituents of neem

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Cited by 36 publications
(25 citation statements)
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“…Among various active phytoconstituents such as nimbin, nimbolide, and limonoids, Azadirachtin is the most significant [16]. Different parts of this plant have been proposed as remedies because of potential properties against a varieties of organisms and other disease-producing factors, including antifungal [17], antibacterial [17,18], anti-inflammatory [17], antiarthritic, antipyretic [19], immunomodulatory [20], antimalarial [19], antitumor, and spermicidal [20] effects. It can not only completely limit growth of Mycobacterium tuberculosis but also exhibit a wide array of antibacterial action against Vibrio cholerae and Klebsiella pneumoniae [21] in vitro .…”
Section: Introductionmentioning
confidence: 99%
“…Among various active phytoconstituents such as nimbin, nimbolide, and limonoids, Azadirachtin is the most significant [16]. Different parts of this plant have been proposed as remedies because of potential properties against a varieties of organisms and other disease-producing factors, including antifungal [17], antibacterial [17,18], anti-inflammatory [17], antiarthritic, antipyretic [19], immunomodulatory [20], antimalarial [19], antitumor, and spermicidal [20] effects. It can not only completely limit growth of Mycobacterium tuberculosis but also exhibit a wide array of antibacterial action against Vibrio cholerae and Klebsiella pneumoniae [21] in vitro .…”
Section: Introductionmentioning
confidence: 99%
“…have a wide range of medicinal properties and are used to treat inflammation, infections, fever, skin diseases and dental disorders Neem constitutes a vast collection of biologically active compounds that are chemically diverse and structurally complex which are effective as antiviral antimicrobial, antimalarial and antibacterial. There are 140 active compounds isolated from different parts of the neem (Kumar et al,2018). Neem leaf and its constituents exhibit antiviral, antifungal, antibacterial, immunomodulatory, antiinflammatory, antihyperglycemic, antiulcer, antimalarial, antioxidant, antimutagenic and anticarcinogenic properties.…”
Section: Bioactive Compounds In Neemmentioning
confidence: 99%
“…The traditional use as antiviral is described for the treatment of animals suffering from bovine and avian poxvirus infections by applying a paste of neem leaves directly on the infected skin [20]. In addition, Neem is considered harmless to animals, insects, humans, birds, and earthworms and has also been approved by the United States Environmental Protection Agency for use as a food crop [21].…”
Section: Introductionmentioning
confidence: 99%
“…Major chemical constituents of neem are terpenes and limonoids. The major active components in the limonoids are azadirachtin, 3-deacetyl-3cinnamoylazadirachtin, 1-tygloyl-3-acetyl-2methoxyazadirachtin, 22,23-dihydro-23βmethoxyazadirachtin, nimbanal, 3tigloylazadirachtol, 3-acetyl-salannoV nimbidioV margocin, margocinin, margocilin, and others [21]. Azadirachtin A is a member of the family of azadirachtins.…”
Section: Introductionmentioning
confidence: 99%