Bioactive glass nanoparticles for periodontal regeneration and applications in dentistry

Biomimetic Mechanism of Action of Fluoridated Toothpaste Containing Proprietary REFIX Technology on the Remineralization and Repair of Demineralized Dental Tissues: An In Vitro Study

“…22 Silicon is claimed to promote more rapid release of Ca and P 23 and induce low negative zeta potential in the biological medium, which has important in vivo effects. 21 As previously reported, substituting phosphate ions (PO 4 ) with silicate ions (SiO 4 ) in hydroxyapatite structures to form calcium silicate also confers a protective effect by inducing the formation of hydroxyapatite after its deposition onto the eroded surfaces. 24 This is particularly due to the induced bioactivity and apatite-forming ability of hydroxyapatite, which is enhanced by the substitution of silicon, or silicate, into the remineralizing hydroxyapatite.…”

“…20 In this way, silicon is regarded as a component of bioactive glass, inducing the formation of nucleation sites for the precipitation of calcium and phosphate ions in the formation of hydroxyapatite. 21 Calcium silicate is then formed, which is responsible for boosting the mineralization processes of saliva via hydroxyapatite nucleation and mineral formation. 22 Silicon is claimed to promote more rapid release of Ca and P 23 and induce low negative zeta potential in the biological medium, which has important in vivo effects.…”

Effect of hydroxyapatite and 45S5 bioactive glass addition on a dental adhesive resin cement

“…According to the theory, external stimuli applied on exposed dentin cause fluid displacement inside dentinal tubules, and thus activating the mechanical receptors that generate a painful response. [8][9][10] To clinically compare two types of cement, Hilton et al 11 observed that more than 50% of the patients reported some sensitivity after crown cementation on vital teeth. Postcementation sensitivity rates have varied widely with values ranging from 3% to 34% in clinical studies.…”

“…3 The most used treatment for dentinal sensitivity is the occlusion of dentinal tubules, which might be achieved using bioactive materials. 9,10 Additionally, various materials evaluated to be suitable repair and filling materials for bone defects and scaffolds for tissue engineering have been proposed for clinical applications in dental practice. These materials include calcium phosphate ceramics, hydroxyapatite (HA) ceramic, bioactive glass (BG), and calcium phosphate cement (CPC).…”

“…These materials include calcium phosphate ceramics, hydroxyapatite (HA) ceramic, bioactive glass (BG), and calcium phosphate cement (CPC). 9,10,[13][14][15][16][17][18][19][20][21] HA is chemically and structurally similar to the mineral components of human bone tissue. Additionally, it can bond with the surrounding bone tissue.…”