2021
DOI: 10.3390/ma14164511
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Bioactive Hydrogels: Design and Characterization of Cellulose-Derived Injectable Composites

Abstract: Cellulose represents a low cost, abundant, and renewable polysaccharide with great versatility; it has a hierarchical structure composed of nanofibers with high aspect ratio (3–4 nm wide, hundreds of μm long). TEMPO-mediated oxidation represents one of the most diffused methods to obtain cellulose nanofibers (CNFs): It is possible to obtain physically crosslinked hydrogels by means of divalent cation addition. The presence of inorganic components, such as calcium phosphates (CaP), can improve not only their me… Show more

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Cited by 13 publications
(21 citation statements)
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“…Figure 4 A shows FT-IR spectra of OBC and Au@OBC samples. The results indicate that, after oxidation, a new peak at 1729 cm −1 has emerged that can be attributed to the C=O stretching vibration of carboxylic acid groups [ 50 ]. The peak located at around 3400 cm −1 is assigned to the stretching vibration of hydroxyl groups (OH).…”
Section: Resultsmentioning
confidence: 99%
“…Figure 4 A shows FT-IR spectra of OBC and Au@OBC samples. The results indicate that, after oxidation, a new peak at 1729 cm −1 has emerged that can be attributed to the C=O stretching vibration of carboxylic acid groups [ 50 ]. The peak located at around 3400 cm −1 is assigned to the stretching vibration of hydroxyl groups (OH).…”
Section: Resultsmentioning
confidence: 99%
“…The morphology of Lipo@PTH NPs was observed with the transmission electron microscope (TEM) (Hitachi, HT7800, Japan) and the sample was negatively stained with 2% phosphotungstic acid 35,36 .…”
Section: Methodsmentioning
confidence: 99%
“…Adding bioactive compounds to hydrogels is an enabling way to boost their bioactivity, which is crucial for cell adhesion and proliferation. [133] Many biomaterials have been investigated to control drug release; however, hydrogels show two distinct advantages among these biomaterials. First, the drug release rate can be controlled in numerous ways, such as changing the crosslinking density, preparing the hydrogel with the controlled hydrophilicity monomers, or containing the proportion to the hydrophilic and hydrophobic monomers.…”
Section: Biomedical Applications Of Smart Hydrogelsmentioning
confidence: 99%