Bioactive Saponins and Glycosides. XXVIII. New Triterpene Saponins, Foliatheasaponins I, II, III, IV, and V, from Tencha (the Leaves of <i>Camellia sinensis</i>)

Medicinal Flowers. XXVI. Structures of Acylated Oleanane-Type Triterpene Oligoglycosides, Yuchasaponins A, B, C, and D, from the Flower Buds of <i>Camellia oleifera</i>&mdash;Gastroprotective, Aldose Reductase Inhibitory, and Radical Scavenging Effects&mdash;

“…[30][31][32] The 1 H-(pyridine-d 5 ) and 13 C-NMR (Table 5) spectra of 1, which were assigned by various NMR experiments, 33) showed signals assignable to a R ]. The oligoglycosidic structure and positions of the two tigloyl groups were clarified by heteronuclear multiple bond connectivity (HMBC) experiment on 1, which showed long-range correlations between the following protons and carbons: 1Ј-H and 3-C; 1Љ-H and 2Ј-C; 1ٞ-H and 3Ј-C; 1ЉЉ-H and 2ٞ-C; 21,22-protons and tigloyl carbonyl carbons.…”

“…[26][27][28] Acid hydrolysis of 2a with 5% aqueous H 2 SO 4 in 1,4-dioxane [1 : 1 (v/v)] liberated barringtogenol C (2b) 35) and four mucosaccharides (D-galactose, Dglucose, D-glucuronic acid, and L-rhamnose), which were identified by GLC. [30][31][32] The 1 H-(pyridine-d 5 ) and 13 C-NMR (Table 5) …”

“…10,11) Furthermore, those oligoglycosides were found to exhibit antiallergic, 6) antidiabetic, 7) antiobesitic, 5,8) gastroprotective, 7,10,11) and platelet aggregation 10,11) activities. In the course of our characterization studies on Camellia speicies [12][13][14][15] and medicinal flowers, [16][17][18][19][20][21] we found that the methanolic (MeOH) extract and its 1-butanol (1-BuOH)-soluble fraction from the flower buds of C. oleifera showed gastroprotective effects on ethanol-or indomethacin-induced gastric mucosal lesions in rats. The 1-BuOH-and ethyl acetate (EtOAc)-soluble fractions exhibited inhibitory activities on rat lens aldose reductase and scavenging effects on 1,1-diphenylpicryl-2-hydrazyl (DPPH) radical and superoxide.…”

Quantitative Analysis of Saponins in a Tea-Leaf Extract and Their Antihypercholesterolemic Activity

“…In green tea leaves, several saponins such as theasaponin B 1 , 1) assamsaponin J, 2) isotheasaponin B 1 -B 3 , 3) foliatheasaponin I-V, 4) and floratheasaponin A 4) have already been identified. In pharmacological studies on tea-leaf saponins, neutrophil-stimulating, 5) antimicrobial, 6) anti-inflammatory, 6) antihypertensive, 7) and anti-allergic 8) effects have been reported.…”

“…[1][2][3][4] We considered that the fragment peak of theasapogenol B measured by LC/TOF-MS could be used to identify the saponins and that the absorption at 280 nm of the cinnamoyl group measured by LC/UV could be used to quantify them.…”