Bioactivities of Syzygium polyanthum (Wight) Walp leaf extract for decreasing diabetic risk

Dewijanti, Indah Dwiatmi; Artanti, Nina; Mangunwardoyo, Wibowo; Hanafi, Muhammad; Abbas, Jamilah; Megawati, Megawati; Minarti, Minarti; Musdalifah, Dian; Meilawati, Lia

doi:10.1063/1.5064297

Cited by 7 publications

(11 citation statements)

References 11 publications

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“…The leaves are mildly astringent or sour and when frying, the flavor intensifies (28). When the leaf is squeezed, it emits a pleasant scent (29). The leaf can be used as a seasoning, while the bark can be used to colour nets and woven bamboo (29).…”

Section: Ethnopharmacologymentioning

confidence: 99%

“…When the leaf is squeezed, it emits a pleasant scent (29). The leaf can be used as a seasoning, while the bark can be used to colour nets and woven bamboo (29). Its wood is used to make houses, furniture, tan fishing nets and colour bamboo matting brown-red (27).…”

Section: Ethnopharmacologymentioning

confidence: 99%

“…1A). S. polyanthum has a taproot and a circular trunk with a slick surface (29). They have leathery leaves that are 6-12 cm long and shaped obovate elliptic or oblong ovate (Fig.…”

Section: Morphologymentioning

confidence: 99%

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Review of Ethnopharmacology, Morpho-Anatomy, Biological Evaluation and Chemical Composition of Syzygium polyanthum (Wight) Walp.

Abdulrahman

2021

Plant Sci. Today

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Syzygium polyanthum (Wight) Walp, a Myrtaceae member, is widely distributed in Southeast Asian countries. The Malays and Indonesians consume the leaves regularly as Ulam (food). It has also been used in traditional medicine to treat several ailments, including gastritis, hypertension, hypercholesterolemia, diarrhea, skin diseases, diabetes and endometriosis. So far, many publications on the biological activity and chemical profile of the plant have been published. There is a need to thoroughly examine the articles and combine the major findings highlighting the potential utility of the species. Thus, the present study aimed to review the ethnopharmacology, morpho-anatomy, biological evaluation and chemical composition of S. polyanthum. In vivo, in vitro antibacterial, antimicrobial, antidiabetic, antioxidants, essential oil and chemical composition of S. polyanthum were searched in Google Scholar, Scopus, Web of Science and PubMed. The investigations revealed that S. polyanthum is a medicinal plant with proven antioxidant, antibacterial, antifungal, antidiabetic and anti inflammatory activities. The plant had a substantial impact on human health. Chemical ingredients extracted and characterised are monoterpene, sesquiterpene, oxygenated monoterpenes, oxygenated sesquiterpenes, phenolic and flavonoid compounds. The review found that the in vitro and in vivo biological evaluation of S. polyanthum was well documented. In order to have conclusive results on the plant leaves efficacy, a well-designed clinical trial is required. Efforts should also be taken for long-term conservation and management.

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Section: Ethnopharmacologymentioning

confidence: 99%

Section: Ethnopharmacologymentioning

confidence: 99%

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Review of Ethnopharmacology, Morpho-Anatomy, Biological Evaluation and Chemical Composition of Syzygium polyanthum (Wight) Walp.

Abdulrahman

2021

Plant Sci. Today

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“…Traditionally, S. polyanthum is widely used as a food ingredient in Indonesian and Malaysian cuisine and used to treat diabetes in Indonesia (Azwar, 2010). It is usually dried, crushed and extracted through soaking in boiled water (Dewijanti et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

“…Since S. polyathum leaves are ethnobotanically used in treating diabetes in Indonesia and Malaysia (Dewijanti, 2018& Burkill, 1935, the National Agency for Drug and Food Control in Indonesia highly regards this medicinal plant. Therefore, we conducted this study to evaluate the scientific evidence available for S. polyanthum in lowering blood glucose levels (BGL).…”

Section: Introductionmentioning

confidence: 99%

Potential of Syzygium polyanthum (Daun Salam) in Lowering Blood Glucose Level: A Review

Rahim¹,

Ahmad²,

Tan³

2021

JST

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Syzygium polyanthum is a herb widely used in Malaysia and Indonesia in cuisines. Traditionally, the herbal decoction of S. polyanthum (daun salam) leaves is often used by diabetic patients in Indonesia. Therefore, our objective is to evaluate the scientific evidence available for S. polyanthum in lowering blood glucose levels (BGL). We systematically searched Pubmed, Google Scholar, Scopus, CENTRAL. LILAC and clinicaltrials.gov databases up to 23rd October 2020 using the keywords “Syzygium polyanthum” and “antidiabetic”. From the selected 413 articles, eight studies involving rodents were included. All results showed a significant effect in lowering BGL without any adverse effects. The possible underlying mechanism of action is attributed to inhibiting intestinal glucose absorption and enhancing glucose uptake by the muscles. Chemical families responsible for the effect were determined as flavonoids, alkaloids and terpenoids. Thus, S. polyanthum leaves showed potential antidiabetic properties, but further research is required to identify the active compounds followed by the safety evaluation of this compound.

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New indications of potential rat intestinal α-glucosidase inhibition by Syzygium zeylanicum (L.) and its hypoglycemic effect in mice

et al. 2019

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Bioactivities of Syzygium polyanthum (Wight) Walp leaf extract for decreasing diabetic risk

Cited by 7 publications

References 11 publications

Review of Ethnopharmacology, Morpho-Anatomy, Biological Evaluation and Chemical Composition of Syzygium polyanthum (Wight) Walp.

Review of Ethnopharmacology, Morpho-Anatomy, Biological Evaluation and Chemical Composition of Syzygium polyanthum (Wight) Walp.

Potential of Syzygium polyanthum (Daun Salam) in Lowering Blood Glucose Level: A Review

New indications of potential rat intestinal α-glucosidase inhibition by Syzygium zeylanicum (L.) and its hypoglycemic effect in mice

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