Bioactivity and phytochemical constituents of marine red seaweeds (Jania rubens,Corallina mediterraneaandPterocladia capillacea)

Abstract

of marine red seaweeds (Jania rubens, Corallina mediterranea and Pterocladia capillacea), J. Taibah Univ. Sci. (2015), http://dx. AbstractSeaweeds are potential renewable resources in the marine environment. The antibacterial activity of Jania rubens, Corallina mediterranea and Pterocladia capillacea were analyzed against human pathogenic bacteria. The present study was performed to investigate the phytochemical constituents of seaweeds, such as alkaloids, flavonoids, steroids, terpenoids and phlobatannins. In this study, we estimated phenols, flavonoids, tannins, pigments and mineral contents and determined the hydrogen peroxide scavenging activity, reducing power and total antioxidant activity of various extracts of selected seaweeds. Phytochemicals were extracted from the three seaweeds using various solvents, such as methanol, ethanol, acetone and chloroform. Among the various extracts, the methanolic extract was found to have the highest reducing power and total antioxidant capacity. We evaluated the seaweeds against Vibrio fluvialis, and Pterocladia capillacea was the most effective at controlling its growth. The highest zone of inhibition was recorded in the methanol extract. The chemical constituents of the seaweeds were characterized by GC-MS, which showed that they contain organic compounds, such as 1,2-benzenedicarboxylic acid.

GC–MS Analysis of Aqueous Extract of Unripe Fruit of Carica papaya

“…Specifically, n-hexadecanoic acid represented the phytocomponent with the lowest concentration among the entire phytocomponents present in AqEUF of C. papaya. Tetradecanoic acid (myristic acid) has been detected in methanolic leaf extracts of J. rubens, C. mediterranea and P. capillacea [26], L. inermis [36] and hexane/acetone leaf extracts of M. edule [29]. Previous studies showed that tetradecanoic acid was the major antibacterial and antioxidant principles isolated from Myristica fragrans (nutmeg) [39,40] as well as antibacterial agent from P. capillacea [41].…”

“…For instance, octadecanoic acid, 2,3-dihydroxypropyl ester, which is an analogue of hexadecanoic acid, 2,3-dihydroxypropyl ester, is present in marine red seaweeds such as Pterochadia capillacea and was noted to exhibit antibacterial activity [26]. Additionally, hexadecanoic acid, 2,3-dihydroxypropyl ester is present in methanolic leaf extract of Spermacoce articularis, which is an important medicinal plant used in Indian folk medicine [27], as well as in chloroform extracts of mosses (Polytrichum commune and Rhytidiadelphus triquetrus), noted for their antimicrobial activity and anticancer activity on cancer cell lines [28].…”

“…Octadecanoic acid from Azadirachta indica (neem) extracts [30] and marine red seaweeds, namely, Jania rubens, Corallina mediterranea and P. capillacea exhibited antibacterial activity against Staphylococcus aureus, Escherichia coli and Salmonella spp [26]. Previous report showed that 9,12-octadecadienoic acid (Z,Z)-, methyl ester from chloroform extract of Albizia adianthifolia (Schumach) [31,32] and methanol extract of Jatropha curcas [33], which is a closely related compound to 12,15-octadecadienioc acid, methyl ester present in AqEUF of C. papaya, impeded cell proliferation and microbial growth.…”

Antioxidant Activity of Some Green and Red Seaweeds From West Coast of Maharashtra, India

“…Green seaweed samples H2O2 activity was about 30% 15 . Maximum activity in methanolic extracted Corollina mediterrane, Pterocladia capillacea and Jania rubens 16 . Highest reducing power activity in aqueous extract of Scytosiphon lomentaria than in ethanol extract 17 .…”

Ethnopharmacological Evaluation of Medicinal Plants for Cytotoxicity Against Various Cancer Cell Lines

“…11,13-Dihydroxy-tetradec-5-ynoic acid, methyl ester was previously identified in Citrullus colocynthis [16]. The other important compounds identified were cis-5,8,11,14,17-Eicosapentaenoic acid trimethylsilyl ester, which is omega 3 fatty acid and plays a vital role as an energy source, maintains membrane stability and cell signaling [17]. The compound 13 was identified as Columbin, a diterpenoid furane lactone, previously extracted from Calumbae radix reported to reduced azoxymethane-induced colon carcinogenesis gave m/z at 358 [18].…”