Bioactivity and toxicity evaluation of infusions from selected Greek herbs

Sotiropoulou, Νefeli-Sofia D.; Flampouri, Evangelia; Skotti, Efstathia; Pappas, Christos; Kintzios, Spyridon; Tarantilis, Petros Α.

doi:10.1016/j.fbio.2020.100598

Cited by 6 publications

(4 citation statements)

References 80 publications

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“…Similarly, Ghafarifarsani et al [42] showed that a 5% inclusion of garlic and oregano extract in carp feed produced no adverse effects. Moreover, EC 50 obtained for CEO in our study was higher (i.e., less toxic) than Greek herbs (e.g., Artemisia dracunculus, Achillea millefolium, Matricaria chamomilla, Salvia pomifera, S. officinalis, and S. fruticosa), which ranged from 0.005 up to 0.71 mg mL −1 [40]. Thus, the toxic activity of CEO implies that its effect must be taken into consideration when administered in fish feed, which justifies the in vivo studies conducted in this work.…”

Section: Acute Toxicity Of Ceomentioning

confidence: 55%

“…The measurement of acute toxicity by the inhibition of V. fischeri bioluminescence using Microtox ® is a well-established and standardized in vitro toxicity test, used in a variety of applications [37], including plant extract toxicity assessment [38][39][40]. Thus, the results obtained with this test can be extrapolated to the effect that the substances would have on animals.…”

Section: Acute Toxicity Of Ceomentioning

confidence: 99%

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Antimicrobial and Toxic Activity of Citronella Essential Oil (Cymbopogon nardus), and Its Effect on the Growth and Metabolism of Gilthead Seabream (Sparus aurata L.)

García‐Márquez

Barany

Ruiz

et al. 2021

Fishes

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Aquaculture procedures usually induce stress that affects the physiological status of fish. For this reason, the inclusion of additives in fish feeds to palliate stress might be a good alternative. This study aimed to assess the antimicrobial activity of citronella (Cymbopogon nardus) essential oil (CEO) against bacterial pathogens and to determine its dietary impact on the growth performance of Sparus aurata. In vitro tests confirmed that CEO possesses antimicrobial activity against several fish-specific pathogens. For the in vivo tests, three experimental groups were fed for 60 days with different concentrations of CEO: CTRL (0 mL kg−1 fish feed); CEO1 (1 mL kg−1 fish feed); and CEO2 (2 mL kg−1 fish feed). At the end of the experiment, the physiological status was characterized. Subsequently, the specimens of the CTRL and CEO2 groups were subjected to a challenge with an injection of Poly I:C for immune stimulation. Although S. aurata individuals tolerated CEO inclusion without compromising growth performance, it significantly reduced glycogen in the CEO2 group, concomitant to an increment of total peripheral leucocytes. Moreover, different hematological profiles’ responsive patterns against an inflammatory stimulus were observed. In conclusion, our results suggest that the use of CEO as a fish feed additive can prevent bacterial outbreaks and improve potential in vivo disease resistance in S. aurata without negatively affecting growth.

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Section: Acute Toxicity Of Ceomentioning

confidence: 55%

Section: Acute Toxicity Of Ceomentioning

confidence: 99%

Antimicrobial and Toxic Activity of Citronella Essential Oil (Cymbopogon nardus), and Its Effect on the Growth and Metabolism of Gilthead Seabream (Sparus aurata L.)

García‐Márquez

Barany

Ruiz

et al. 2021

Fishes

View full text Add to dashboard Cite

show abstract

“…These were higher than values reported to botanically identified sample (BS), which may be explained by differences in cultivation practices and the way the plants were processed. For example, the drying time may increase the degradation of plant bioactive compounds, whereas soil characteristics and precipitation conditions may affect the biosynthesis of secondary metabolites [ 9 , 10 ].…”

Section: Resultsmentioning

confidence: 99%

“…Nevertheless, data on the content of bioactive compounds, antioxidant capacity, and volatile compounds, among other parameters of this plant, to compare botanically identified and commercialized samples and their infusions are scarce in the literature. Since it is well known that various factors such as climate, processing, and storage conditions may influence the content of bioactive compounds and the volatile fraction of medicinal plants [ 9 , 10 ], there is a clear need for further studies.…”

Section: Introductionmentioning

confidence: 99%

Bauhinia forficata Link Infusions: Chemical and Bioactivity of Volatile and Non-Volatile Fractions

et al. 2022

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This study aimed to evaluate Bauhinia forficata infusions prepared using samples available in Rio de Janeiro, Brazil. As such, infusions at 5% (w/v) of different brands and batches commercialized in the city (CS1, CS2, CS3, and CS4) and samples of plant material botanically identified (BS) were evaluated to determine their total phenolic and flavonoid contents (TPC and TFC), antioxidant capacity (ABTS•+, DPPH•, and FRAP assays), phytochemical profile, volatile compounds, and inhibitory effects against the α-amylase enzyme. The results showed that infusions prepared using BS samples had lower TPC, TFC and antioxidant potential than the commercial samples (p < 0.05). The batch averages presented high standard deviations mainly for the commercial samples, corroborating sample heterogeneity. Sample volatile fractions were mainly composed of terpenes (40 compounds identified). In the non-volatile fraction, 20 compounds were identified, with emphasis on the CS3 sample, which comprised most of the compounds, mainly flavonoid derivatives. PCA analysis demonstrated more chemical diversity in non-volatile than volatile compounds. The samples also inhibited the α-amylase enzyme (IC50 value: 0.235–0.801 mg RE/mL). Despite the differences observed in this work, B. forficata is recognized as a source of bioactive compounds that can increase the intake of antioxidant compounds by the population.

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Optimization of Ultrasound Extraction of Phenolic Compounds from Tarragon (Artemisia dracunculus L.) Using Box–Behnken Design

Kutlu

Kamiloğlu

Elbir

2022

Biomass Conv. Bioref.

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Bioactivity and toxicity evaluation of infusions from selected Greek herbs

Cited by 6 publications

References 80 publications

Antimicrobial and Toxic Activity of Citronella Essential Oil (Cymbopogon nardus), and Its Effect on the Growth and Metabolism of Gilthead Seabream (Sparus aurata L.)

Antimicrobial and Toxic Activity of Citronella Essential Oil (Cymbopogon nardus), and Its Effect on the Growth and Metabolism of Gilthead Seabream (Sparus aurata L.)

Bauhinia forficata Link Infusions: Chemical and Bioactivity of Volatile and Non-Volatile Fractions

Optimization of Ultrasound Extraction of Phenolic Compounds from Tarragon (Artemisia dracunculus L.) Using Box–Behnken Design

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