Bioactivity of hydroxyapatite/wollastonite composite films deposited by pulsed laser

Chen, Zhenghong; Zhai, Jiqiang; Wang, Diangang; Chen, Chuanzhong

doi:10.1016/j.ceramint.2018.03.013

Cited by 18 publications

(5 citation statements)

References 30 publications

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“…The discussed wavenumbers for a functional group in the FT-IR spectra con rm the association of MMT and HA have been incorporated successfully in the Biopolymer composite. Respective planes of 2θ values (002), ( 112), ( 004) and (431) show that the prepared HA has crystalline corresponding to Hydroxyapatite [42]. The X-ray diffraction peak of MMT at 2θ = 7º was not observed in the HA/MMT matrix, due to exfoliation.…”

Section: Resultsmentioning

confidence: 98%

Fabrication of Biologically Active Fish Bone Derived Hydroxyapatite and Montmorillonite Blended Sodium Alginate Composite for In-Vitro Drug Delivery Studies

Ahamed

Manimohan

Kalaivasan

2022

J Inorg Organomet Polym

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Fishbone comprising hydroxyapatite (bio-ceramic) is regularly viewed as a natural resource for biological and pharmaceutical applications. In this study, hydroxyapatite has been prepared from shbone waste using thermal calcination method. The composite hydroxyapatite-montmorillonite-sodium alginate was synthesized by co-precipitation method. Various functional groups of biocomposite were characterised using Fourier Transform infrared spectroscopy (FT-IR). Thermal gravimetric analysis (TGA) and X-ray diffraction studies were exhibited the thermal stability and crystallinity of biocomposite respectively. The morphological surface of composites was studied using scanning electron microscopy (SEM). The synthesized composite was designed to study the enhanced biological potential such as antibacterial, antioxidant, antidiabetic, drug loading and the drug releasing ability. Antioxidant and anti-diabetic analysis of composite were studied using Phosphomolybdenum and α-Amylase inhibitory method respectively. The drug releasing ability of compounds (Doxorubicin and Curcumin) were investigated by UV-spectrophotometry method at different pH medium (pH = 5.5, 6.8 and 7.4). Additionally, In-vitro kinetic studies were carried out on composite to determine the drug releasing ability of doxorubicin and curcumin.

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Section: Resultsmentioning

confidence: 98%

Fabrication of Biologically Active Fish Bone Derived Hydroxyapatite and Montmorillonite Blended Sodium Alginate Composite for In-Vitro Drug Delivery Studies

Ahamed

Manimohan

Kalaivasan

2022

J Inorg Organomet Polym

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“…The sample was immersed in SBF to observe the formation rate of new apatite on the coating surface to evaluate the biological activity of the coatings . In SBF, the coating begins to dissolve, at which point the ions migrate from the coating to the solution for ion exchange, and then, the ions from the solution are deposited onto the coating surface to form a new apatite layer …”

Section: Results and Discussionmentioning

confidence: 99%

“…29 In SBF, the coating begins to dissolve, at which point the ions migrate from the coating to the solution for ion exchange, and then, the ions from the solution are deposited onto the coating surface to form a new apatite layer. 30 Figure 5 shows the microtopography of the coatings after immersion at 37 °C for 7 days. The surface of HA coatings with and without annealing treatment was covered with the newly formed apatite layer, which did not lead to a significant change in the morphology.…”

Section: Methodsmentioning

confidence: 99%

Formation of Porous Apatite Layer after Immersion in SBF of Fluorine-Hydroxyapatite Coatings by Pulsed Laser Deposition Improved in Vitro Cell Proliferation

Cao

Lian

Liu

2020

ACS Appl. Bio Mater.

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Fluorine (F), a trace element in bone tissues, promotes cell proliferation and colonization. In this study, fluorinehydroxyapatite (F-HA) coating was manufactured onto titanium substrates using pulsed laser deposition (λ = 1024 nm). The results confirmed that the surface roughness of F-HA coatings was the highest when the deposition time was 60 min. To evaluate the biological activity of the coatings, the coatings were immersed in simulated body fluids at 37 °C for 7 days. It was clearly observed that a new apatite layer showed a micro/nano foam-like porous structure. After annealing treatment, the F-HA coating can promote the transformation of the calcium phosphate crystal phase into the HA phase. Moreover, the mass of F-HA coatings with annealing was increased by 2.3% after immersion. In vitro cytocompatibility of the coatings was evaluated; the cell adhesion and proliferation exposed to F-HA coatings were significantly stimulated and promoted when compared with the control group in the first and second weeks of co-culture (p < 0.05). Thus, F-HA coatings can potentially act as osteoinductive materials for surface functionalization of the bone tissue scaffold.

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“…Slightly different actions for similar samples in SBF solution have been observed in other studies. For example, Chen et al determined that in the early soaking stage the dissolution action dominates [45]. Following this, new precipitates form, indicating that precipitation reaction is dominating.…”

Section: Resultsmentioning

confidence: 99%

“…Neither etching behavior, nor additional precipitates were observed. Probably, the dissolution and the precipitation processes proceeded simultaneously, without any domination [45]. However, SEM images obtained using secondary electron or backscattered electron modes give poorly distinguishable results among different calcium phosphate phases [46][47][48][49].…”

Section: Resultsmentioning

confidence: 99%

Characterization of Sol-Gel Derived Calcium Hydroxyapatite Coatings Fabricated on Patterned Rough Stainless Steel Surface

et al. 2019

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Sol-gel derived calcium hydroxyapatite (Ca10(PO4)6(OH)2; CHA) thin films were deposited on stainless steel substrates with transverse and longitudinal patterned roughness employing a spin-coating technique. Each layer in the preparation of CHA multilayers was separately annealed at 850 °C in air. Fabricated CHA coatings were placed in simulated body fluid (SBF) for 2, 3, and 4 weeks and investigated after withdrawal. For the evaluation of obtained and treated with SBF coatings, diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS), X-ray diffraction (XRD) analysis, Raman spectroscopy, XPS spectroscopy, scanning electron microscopy (SEM) analysis, and contact angle measurements were used. The tribological properties of the CHA coatings were also investigated in this study.

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Bioactivity of hydroxyapatite/wollastonite composite films deposited by pulsed laser

Cited by 18 publications

References 30 publications

Fabrication of Biologically Active Fish Bone Derived Hydroxyapatite and Montmorillonite Blended Sodium Alginate Composite for In-Vitro Drug Delivery Studies

Fabrication of Biologically Active Fish Bone Derived Hydroxyapatite and Montmorillonite Blended Sodium Alginate Composite for In-Vitro Drug Delivery Studies

Formation of Porous Apatite Layer after Immersion in SBF of Fluorine-Hydroxyapatite Coatings by Pulsed Laser Deposition Improved in Vitro Cell Proliferation

Characterization of Sol-Gel Derived Calcium Hydroxyapatite Coatings Fabricated on Patterned Rough Stainless Steel Surface

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