Bioanalytical applications of Mössbauer spectroscopy

Abstract

Data on the applications of Mössbauer spectroscopy in the transmission (mainly on 57Fe nuclei) and emission (on 57Co nuclei) variants for analytical studies at the molecular level of metal-containing components in a wide range of biological objects (from biocomplexes and biomacromolecules to supramolecular structures, cells, tissues and organisms) and of objects that are participants or products of biological processes, published in the last 15 years are discussed and systematized. The prospects of the technique in its biological applications, including the developing fields (emission variant, use of synchrotron radiation), are formulated. The bibliography includes 248 references.

Micromagnetic and morphological characterization of heteropolymer human ferritin cores

“…Mössbauer spectroscopy has uniquely contributed to elucidating the electronic and micromagnetic properties of ferritin, magnetoferritin, and other apoferritin derived magnetic nanoparticles, 43–48 while bioanalytical applications of Mössbauer spectroscopy have been recently reviewed. 49…”

“…Mössbauer spectroscopy has uniquely contributed to elucidating the electronic and micromagnetic properties of ferritin, magnetoferritin, and other apoferritin derived magnetic nanoparticles, [43][44][45][46][47][48] while bioanalytical applications of Mössbauer spectroscopy have been recently reviewed. 49 Herewith, we present high resolution images obtained via high-angle annular dark-eld scanning transmission electron microscopy (HAADF-STEM) of recombinant human H-rich heteropolymer (H 21 /L 3 ) ferritin, and recombinant human L-rich heteropolymer (H 2 /L 22 ) ferritin reconstituted to 1000 Fe/ protein, to better understand the effect of protein composition on the shape and crystallinity of the core. We complement these measurements with EELS and 57 Fe Mössbauer spectroscopy 45 to ascertain the iron oxidation state in the biomineral cores and probe their micromagnetic properties.…”

“…In many medical and biotechnological applications, the magnetization and magnetic relaxation properties of the resulting nanoparticles are of interest, as they must be tailored to specific applications. Mӧssbauer spectroscopy has uniquely contributed to elucidating the electronic and micromagnetic properties of ferritin, magnetoferritin, and other apoferritin derived magnetic nanoparticles [43][44][45][46][47][48] , while bioanalytical applications of Mӧssbauer spectroscopy have been recently reviewed 49 .…”

Fourier Transform Infrared (FTIR) Spectroscopic Study of Biofilms Formed by the Rhizobacterium Azospirillum baldaniorum Sp245: Aspects of Methodology and Matrix Composition

“…The diverse field of microbiology has been progressively developing over the last decades, largely owing to the steadily growing applications of a range of modern molecular spectroscopy techniques that provide molecular-level information on complicated microbiological objects and allow for successfully solving various bioanalytical problems, often in situ or in vivo (see, e.g., [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 ]). We would like to emphasize the informativity of very relevant vibrational spectroscopic techniques, including various modifications of infrared (conventional absorption [ 2 , 7 , 11 , 16 ], diffuse reflectance [ 3 , 6 ], attenuated total reflectance (ATR) [ 5 , 17 ] and surface-enhanced absorption [ 15 ] modes; 2D infrared [ 8 ]) and Raman [ 1 , 2 , 13 ] spectroscopies, as well as their combinations [ 4 , 14 ]; vibrational circular dichroism [ 12 ], optical activity [ 9 ], etc.…”

New aspects of the photodegradation of iron(III) citrate: spectroscopic studies and plant-related factors

“…Therefore, such method gives reliable information on the oxidation state and chemical form of Fe in the original solution [30][31][32]. Despite not being a routine biological technique, Mössbauer spectroscopy showed a significant analytical potential in investigating a wide range of biological objects (from biocomplexes and biomacromolecules to supramolecular structures, cells, tissues, and organisms) [33][34][35]. In the present work, biological relevance of the photodegradation was also studied with the same method in the model plant after foliar treatments with Fe III citrate solution.…”