Bioavailability of Hg and Se from seafood after culinary treatments

Schmidt, Lucas; Figueroa, Julio Alberto Landero; Vecchia, Paula Dalla; Duarte, Fábio A.; Mello, Paola A.; Caruso, Joseph A.; Flores, Érico M.M.

doi:10.1016/j.microc.2018.03.009

Cited by 15 publications

(8 citation statements)

References 43 publications

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“…The mixture of porcine pancreatin (Sigma-Aldrich ® , St. Louis, MO, USA) and bile salts (Sigma-Aldrich ® , St. Louis, MO, USA) was dissolved in 1 mol/L sodium bicarbonate (POCH, Gliwice, Poland) to form a mixture of intestinal solution. The PIPES buffer (Sigma-Aldrich ® , St. Louis, MO, USA) was prepared by dissolving it in water, and the pH was adjusted to 7.5 with 3 mol/L HCl [ 39 ].…”

Section: Methodsmentioning

confidence: 99%

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Comparison of the Potential Relative Bioaccessibility of Zinc Supplements—In Vitro Studies

Ośko,

Pierlejewska,

Grembecka

2023

Nutrients

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The aim of this study was to determine the potential relative bioaccessibility of zinc (Zn) from selected dietary supplements during in vitro digestion. The bioaccessibility of Zn was evaluated in dietary supplements differing in the pharmaceutical form, content, dose, and chemical form of the element. The content of Zn was determined by flame atomic absorption spectrometry. The applied method was validated, and results were characterised by good linearity (R2 = 0.998), recovery (109%), and accuracy (0.02%). As a result of the tests conducted, it was found that the bioaccessibility of Zn from dietary supplements varied and ranged from 1.1% to 9.4%. The highest bioaccessibility was found for zinc diglycinate and the lowest for zinc sulphate. In 9 out of 10 tested dietary supplements, the determined Zn content was higher than the one declared by the producer (up to 161%). The estimated tolerable upper intake level (UL) was exceeded by five of the analysed dietary supplements (123–146%). The analysed dietary supplements were assessed in terms of compliance with the information contained on the product packaging, based on current Polish and European legal regulations. The qualitative assessment was performed according to the United States Pharmacopoeia (USP) guidelines.

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Section: Methodsmentioning

confidence: 99%

“…Then, the membranes were washed three times with MiliQ water. The membranes prepared in this manner were stored in MiliQ water until they were used for research [ 39 ].…”

Section: Methodsmentioning

confidence: 99%

Comparison of the Potential Relative Bioaccessibility of Zinc Supplements—In Vitro Studies

Ośko,

Pierlejewska,

Grembecka

2023

Nutrients

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“…11 The consumption of contaminated sh, sea mammals and ground water are the prominent environmental sources of Hg exposure in humans. 11,12 It forms quite stable complexes with sulydryl (-SH) groups in the human body forming mercaptides having mobility through the tissues, 13 which lead to the inactivation of numerous enzyme reactions, amino acids and sulfur containing antioxidants such as N-acetyl cysteine (NAC), alpha-lipoic acid (ALA), and glutathione (GSH) and makes it quite toxic to the human being (cf. following general reaction).…”

Section: Introductionmentioning

confidence: 99%

A novel catalytic kinetic method for the determination of mercury(ii) in water samples

et al. 2020

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“…In humans, Se plays an important role in preventing cellular damage induced by free radicals, by incorporation into antioxidant enzymes (selenoproteins) [ 52 ], and it has different biological roles depending on the specie, being essential for the brain [ 53 ], regulating thyroid function, and helping the immune system. It was also shown that selenoproteins can help reduce Hg toxicity in seafood [ 54 ]. A selenoprotein is any protein that includes a SeCys amino-acid residue.…”

Section: Introductionmentioning

confidence: 99%

Selenium Analysis and Speciation in Dietary Supplements Based on Next-Generation Selenium Ingredients

Constantinescu-Aruxandei

Frîncu

Capră

et al. 2018

Nutrients

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Selenium is essential for humans and the deficit of Se requires supplementation. In addition to traditional forms such as Se salts, amino acids, or selenium-enriched yeast supplements, next-generation selenium supplements, with lower risk for excess supplementation, are emerging. These are based on selenium forms with lower toxicity, higher bioavailability, and controlled release, such as zerovalent selenium nanoparticles (SeNPs) and selenized polysaccharides (SPs). This article aims to focus on the existing analytical systems for the next-generation Se dietary supplement, providing, at the same time, an overview of the analytical methods available for the traditional forms. The next-generation dietary supplements are evaluated in comparison with the conventional/traditional ones, as well as the analysis and speciation methods that are suitable to reveal which Se forms and species are present in a dietary supplement. Knowledge gaps and further research potential in this field are highlighted. The review indicates that the methods of analysis of next-generation selenium supplements should include a step related to chemical species separation. Such a step would allow a proper characterization of the selenium forms/species, including molecular mass/dimension, and substantiates the marketing claims related to the main advantages of these new selenium ingredients.

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Bioavailability of Hg and Se from seafood after culinary treatments

Cited by 15 publications

References 43 publications

Comparison of the Potential Relative Bioaccessibility of Zinc Supplements—In Vitro Studies

Comparison of the Potential Relative Bioaccessibility of Zinc Supplements—In Vitro Studies

A novel catalytic kinetic method for the determination of mercury(ii) in water samples

Selenium Analysis and Speciation in Dietary Supplements Based on Next-Generation Selenium Ingredients

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