Biobank Governance: Trends and Perspectives

Abstract

Biobanks are a challenge and topic for governance. Today, biobanks are identified as a biomedical scientific/infrastructural development that warrants a political/legal/ethical reaction with the goal to integrate biobanks into the preexisting fabric of regulation, medicine, law and society. Biobank governance is always a response to sociocultural challenges and requires the building of trust, acceptance, and careful political negotiation. Biobanks are regulated in networks of governance in which the state is one actor next to others, and the ordering and structuring of the interaction between biobanks, society, and politics operates through a variety of actors, on different levels and along particular rationalities. Such networks of governance reflect, to some extent, a postregulatory state in which governance has become a complicated architecture and field of action involving a multitude of forces and rationalities. Biobank governance is still a relatively new field of political-legal intervention and it will be crucial for the future of biobanks to establish governance regimes that appropriately link research with society and politics.

The Ethics of Research Biobanking: A Critical Review of the Literature

“…What is the role of Institutional Review Boards/Research Ethics Committees and can the system be rethought to better facilitate biobank research? (Gottweis and Zatloukal, 2007;Caulfield and Outerbridge, 2002).…”

Specialized biobank for Diabetes Research: current prospect

“…They also differ in scope such as disease-oriented and population-based biobanks [8]. Disease-oriented biobanks are most often hospital-based and are meant for epidemiological studies.…”

“…Sharing of biospecimens with diabetes biobank, for example, the New National Biobank of the Danish Center for Strategic Research on DD2 will not only help in better research outcomes, but also in the development of national and international strategies to prevent and cure diabetes complications. The established, potential upcoming, and specialized biobanks have the ability to support the following: i) research that has the potential to understand disease epidemiology and other associated diseases in relation to risk factors, ii) support tissue biomarkers in pharmaceutical research and development, iii) interdisciplinary clinical research, iv) future analysis of biospecimens using an high throughput omics technologies, and v) allow long-term recessionproof funding to support ongoing research activities and employ the principles of economies of scale including duplication [8,13].…”

Biobanks Are an Essential Tool for Transplantation. History, Current State, Perspectives

“…В своей работе Gottweis и Zatloukal определяют четыре основных типа исследовательских биобан-ков [37]: 1) биобанки «клиника-контроль», содержащие об-разцы от пациентов с конкретной патологией и образцы здоровых людей из группы контроля; 2) лонгитюдные популяционные биобанки, собира-ющие образцы от представителей популяции в течение длительного времени; 3) изолированные популяционные биобанки для изучения конкретных популяций, отличающихся определенными условиями жизни и гомогенным генетическим составом; 4) регистры близнецов, содержащие образцы, по-лученные от однояйцевых и двуяйцевых близне-цов. В обзорной статье Rebulla et al [38] предлага-ют более широкую классификацию, включающую шесть типов биобанков: 1) банки образцов тканей, получаемых в ходе рабо-ты патологоанатомических отделений; 2) популяционные биобанки; 3) регистры близнецов; 4) биобанки, ориентированные на конкретное забо-левание; 5) биобанки, содержащие образцы, получаемые не от человека; 6) хранилища целых органов.…”