BIOCHEMICAL AND SEROLOGICAL PROPERTIES OF <i>STREPTOCOCCUS MUTANS</i> FROM VARIOUS HUMAN AND ANIMAL SOURCES

Perch, Beate; Kjems, E.; Ravn, T.

doi:10.1111/j.1699-0463.1974.tb02338.x

Cited by 79 publications

(13 citation statements)

References 17 publications

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“…Most of the studies, however, have reported the occurrence of serotype e with highest prevalence that ranged from 2% to 30% followed by serotypes: f and k in the range of 1-25% and around 5% respectively [Table 2]. [171819202122232425262728] Since the findings of our study are in contrary to those that have been observed earlier, we speculate that this could be due to a shift in S. mutans serotype in subjects from this region. Such serotype shifts have been reported elsewhere in other strains such as Streptoccocus agalactiae from Group B Streptococcus for example, where in S. agalactiae serotype Ia was found to occur consistently with a higher prevalence in North American population relative to those from other geographic regions ( P < 0.005).…”

Section: Discussioncontrasting

confidence: 94%

Serotype specific polymerase chain reaction identifies a higher prevalence of streptococcus mutans serotype k and e in a random group of children with dental caries from the Southern region of India

Rao

Austin

2014

Contemp Clin Dent

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Background:The development of dental caries has been associated with the oral prevalence of Streptococcus mutans. Four serotypes of S. mutans have been reported, namely serotype c, e, f, and k that are classified based on the composition and linkages of cell wall polysaccharides, response to physiological reactions, sero-specificity and 16s rRNA homology. Although the oral prevalence of S. mutans serotype c in Indian subjects with or without caries is known, the prevalence of the other three serotypes, e, f, and k are not known. Hence in this study, we have investigated the occurrence of the e, f, and k serotypes in children with or without caries within the age group of 6-12 years.Materials and Methods:Genomic DNA isolated from whole saliva of caries active (CA) and caries free (CF) groups were first screened for the presence of S. mutans by strain specific polymerase chain reaction (PCR). Those samples that tested positive for the presence of S. mutans were further analyzed by serotype specific PCR to identify the prevalence of the serotypes.Results:Strain specific PCR indicated a higher prevalence of S. mutans in CA group (80%) relative to CF group (43%). Further analysis of the S. mutans positive samples in both groups indicated a higher prevalence of serotype k and e, followed by serotype f in CA group.Conclusion:The present data clearly establishes a novel S. mutans serotype prevalence hierarchy in children from this region, compared with those that have been reported elsewhere. Besides, the data are also clinically significant as the occurrence of serotype k has been associated with infective endocarditis.

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Section: Discussioncontrasting

confidence: 94%

Serotype specific polymerase chain reaction identifies a higher prevalence of streptococcus mutans serotype k and e in a random group of children with dental caries from the Southern region of India

Rao

Austin

2014

Contemp Clin Dent

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“…S.m. group consists of 7 species that can be classified into 9 serotypes on the basis of saccharide antigens (Table III) (Facklam 2002;Perch et al 1974;Nakano et al 2007). …”

Section: Streptococcus Mutans Groupmentioning

confidence: 99%

Point-of-care salivary microbial tests for detection of cariogenic species — Clinical relevance thereof — review

2010

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Dental caries is a highly prevalent multifactorial disease that can result in serious health impairment. It was shown that oral bacteria play a significant role in caries development. Point-of-care (POC) salivary microbial tests for detection of cariogenic species have been investigated as a potential tool for caries risk assessment. This review aims to evaluate clinical relevance of these tests in the light of recent scientific evidence. Methodology involved PubMed search using key words salivary microbial tests, cariogenic bacteria and caries risk prediction. Articles obtained by the search were cross-referenced to obtain further sources. Specificity and negative-predictive value of these tests are higher than their sensitivity and positive value. Predictive power of the POC salivary microbial tests as a single predictor is generally weak, although it increases when included in multifactorial models for caries prediction. Literature findings support the use of these tests for screening of at-risk individuals in a population of young preschool children without visible caries and for motivation of subjects on individual level. POC salivary microbial tests are simple and inexpensive and, therefore, may be advantageous from public health perspective.

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“…In addition, detection sensitivity has been shown to be higher with such a PCR method as compared to a conventional immunodiffusion technique [32]. The detection rate of serotype c strains has been reported to be the highest (ranging from 64.5 to 89.3%), followed by serotype e (from 7.0 to 26.1%) ( Table 2) [29,[31][32][33][34][35][36][37][38][39][40][41][42][43]. In contrast, the detection rate of serotype f is estimated to be less than 5%, based on the results of previous studies, though a higher frequency was reported in early studies.…”

Section: Serotypes Of S Mutansmentioning

confidence: 99%

“…The prevalence rates of serotypes of S. mutans presented in past articles are summarized in Table 2 [29,[31][32][33][34][35][36][37][38][39][40][41][42][43]. There are several methods used to determine serotypes, among which an immunodiffusion method using cell extract antigens and serotype-specific antisera is commonly utilized.…”

Section: Serotypes Of S Mutansmentioning

confidence: 99%

Streptococcus mutans and cardiovascular diseases

Nakano

Nomura

Ooshima

2008

Japanese Dental Science Review

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BIOCHEMICAL AND SEROLOGICAL PROPERTIES OF STREPTOCOCCUS MUTANS FROM VARIOUS HUMAN AND ANIMAL SOURCES

Cited by 79 publications

References 17 publications

Serotype specific polymerase chain reaction identifies a higher prevalence of streptococcus mutans serotype k and e in a random group of children with dental caries from the Southern region of India

Serotype specific polymerase chain reaction identifies a higher prevalence of streptococcus mutans serotype k and e in a random group of children with dental caries from the Southern region of India

Point-of-care salivary microbial tests for detection of cariogenic species — Clinical relevance thereof — review

Streptococcus mutans and cardiovascular diseases

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