Biochemical Composition of<i>Curcuma longa</i>L. Accessions

Niranjan, Abhishek; Singh, Shweta; Dhiman, Manjul; Tewari, Shri Krishna

doi:10.1080/00032719.2012.751541

Cited by 27 publications

(11 citation statements)

References 34 publications

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“…Turmeric is a top‐selling dietary supplement across the world (Andrew and Izzo, ). One group of active compounds in turmeric are curcuminoids, which has several forms of curcumin with the most abundant being curcumin I, chemical name diferuloylmethane (Niranjan et al ., ) (Fig. ).…”

Section: Introductionmentioning

confidence: 93%

Potential Role of Curcumin Against Biofilm‐Producing Organisms on the Skin: A Review

Vaughn

Haas

Burney

et al. 2017

Phytotherapy Research

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Turmeric root (Curcuma longa) is predominantly used as a spice, but has also long been known to possess antimicrobial, analgesic, antiinflammatory, and anticancer properties. One predominant group of active compounds in turmeric are curcuminoids, namely bright yellow-pigmented curcumin. While modern science has yet to fully investigate the therapeutic claims of turmeric and its derivatives, results have proven promising in decreasing pain and inflammation in arthritis, improving insulin sensitivity in diabetes, and even curing a variety of infections. The purpose of this review is to discuss the potential for curcumin as an agent against microbial infections, with a special focus on the skin and in the development of bacterial biofilms. Curcumin has demonstrated bactericidal efficacy against a variety of infections when administered with antibiotics in several clinical studies, with consistent antimicrobial activity demonstrated in vitro, as well as in urinary tract infections, gingival infections, and chronic wound infections. Hypothesized mechanisms of action include curcumin's ability to perturb bacterial membranes, disturb protofillament assembly, and even impair bacterial virulence factors. Further investigation is needed to fully understand which organisms are most susceptible to the effects of curcumin and how curcumin can be implemented in dermatology to treat skin conditions such as chronic wounds and acne vulgaris. Copyright © 2017 John Wiley & Sons, Ltd.

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Section: Introductionmentioning

confidence: 93%

Potential Role of Curcumin Against Biofilm‐Producing Organisms on the Skin: A Review

Vaughn

Haas

Burney

et al. 2017

Phytotherapy Research

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“…Turmeric products have been characterized as safe by several committees including the Food and Drug Administration (FDA) in the USA, the Joint Expert Committee of the Food and Agriculture Organization/World Health Organization (FAO/WHO), the Natural Health Products Directorate of Canada, and the Codex Alimentarius [8, 9]. Major phytoconstituents of turmeric are diarylheptanoids, which occur in a mixture termed curcuminoids that consists of two methoxylated phenols connected by two α , β unsaturated carbonyl groups that exist in a stable enol form, and they generally make up approximately 1−6% of turmeric by dry weight [10, 11]. The product consists essentially of three major compounds (Figure 1): curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, typically 60−70% of a crude extract), demethoxycurcumin (1-(4-hydroxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)-hepta-1,6-diene-3,5-dione, 20−27%), and bisdemethoxycurcumin (1,7-bis-(4-hydroxyphenyl)-hepta-1,6-diene-3,5-dione, 10−15%) [6].…”

Section: Curcuminmentioning

confidence: 99%

Gut Microbiota as a Prospective Therapeutic Target for Curcumin: A Review of Mutual Influence

Zam

2018

Journal of Nutrition and Metabolism

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Background Turmeric is a spice that has recently received much interest and has been widely used in Ayurvedic medicine. Turmeric products are diarylheptanoids and have been characterized as safe. They are termed as curcuminoids that consists essentially of three major compounds: curcumin, demethoxycurcumin, and bisdemethoxycurcumin. Curcumin is a lipophilic polyphenol that has poor systemic bioavailability and suffers from biotransformation by human intestinal microflora to yield different metabolites that are easily conjugated to glucuronides and sulfate O-conjugated derivatives. Recently, an increasing number of studies have indicated that dysbiosis is linked with many metabolic diseases, though gut microbiota could be a novel potential therapeutic target. Scope and Approach Thus, it is suspected that curcumin and its derivatives exert direct regulative effects on the gut microbiota which could explain the paradox between curcumin's poor systemic bioavailability and its widely reported pharmacological activities. Key Findings and Conclusions This article summarizes a range of studies that highlight the interaction between curcumin and gut microbiota and considers opportunities for microbiome-targeting therapies using turmeric extract.

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“…In general, sesquiterpenes are the predominant phytochemical group in C. longa rhizome oil [33]. More concretely, ar-, αand β-turmerones are usually the major and most representative components [34,35], although numerous intrinsic and extrinsic elements may influence in their quality and quantity [36][37][38][39][40][41]. Nevertheless, this chemical composition is different from the essential oil extracted from the aerial parts in which monoterpenes (α-phellandrene, terpinolene, 1,8-cineole, etc.)…”

Section: Introductionmentioning

confidence: 99%

Curcuma longa L. Rhizome Essential Oil from Extraction to Its Agri-Food Applications. A Review

Ibáñez

Blázquez

2020

Plants

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Curcuma longa L. rhizome essential oil is a valuable product in pharmaceutical industry due to its wide beneficial health effects. Novel applications in the agri-food industry where more sustainable extraction processes are required currently and safer substances are claimed for the consumer are being investigated. This review provides information regarding the conventional and recent extraction methods of C. longa rhizome oil, their characteristics and suitability to be applied at the industrial scale. In addition, variations in the chemical composition of C. longa rhizome and leaf essential oils regarding intrinsic and extrinsic factors and extraction methods are also analysed in order to select the most proper to obtain the most efficient activity. Finally, the potential applications of C. longa rhizome oil in the agri-food industry, such as antimicrobial, weedicide and a food preservative agent, are included. Regarding the data, C. longa rhizome essential oil may play a special role in the agri-food industry; however, further research to determine the application threshold so as not to damage crops or affect the organoleptic properties of food products, as well as efficient encapsulation techniques, are necessary for its implementation in global agriculture.

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Biochemical Composition ofCurcuma longaL. Accessions

Cited by 27 publications

References 34 publications

Potential Role of Curcumin Against Biofilm‐Producing Organisms on the Skin: A Review

Potential Role of Curcumin Against Biofilm‐Producing Organisms on the Skin: A Review

Gut Microbiota as a Prospective Therapeutic Target for Curcumin: A Review of Mutual Influence

Curcuma longa L. Rhizome Essential Oil from Extraction to Its Agri-Food Applications. A Review

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