Biochemical Identification of Elastin in Periosteum and Pericranium

Gd, Rooker; Gn, Steins; Lj, Tate; Fw, Keeley

doi:10.1097/00003086-198010000-00036

Cited by 7 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The variability in the thickness and alignment of elastin fibres observed within the repair tissue biopsies could be representative of the level of maturity of the repair tissue. Consistent with results presented here, elastin fibres within the periosteum have previously been described 43 . As far as we are aware, this is the first published study to reveal the presence of elastin in Chondrogide Ò .…”

Section: Discussionsupporting

confidence: 92%

A histological comparison of the repair tissue formed when using either Chondrogide® or periosteum during autologous chondrocyte implantation

McCarthy

Roberts

2013

Osteoarthritis and Cartilage

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 92%

A histological comparison of the repair tissue formed when using either Chondrogide® or periosteum during autologous chondrocyte implantation

McCarthy

Roberts

2013

Osteoarthritis and Cartilage

View full text Add to dashboard Cite

show abstract

“…On the outer side the stretched periosteal tissues remain adherent to the bone, but on the inner side the fibrous layer becomes widely separated from it. This separation of the periosteum, seen also in straight transplants (Feik and Storey, 1983), is thought to be due to the contraction of the periosteum, which, containing both elastic and fibrous elements (Tonna, 1974;Azuma et al, 1979;Rooker et al, 1980), behaves elastically (Crilly, 1972;Harkness and Trotter, 1978). As the transplant is bent, the bone moves through the supporting soft tissues and the periosteum is held against the bone on the outer side.…”

Section: Discussionmentioning

confidence: 99%

Remodeling of bone and bones: Effects of altered mechanical stress on the regeneration of transplanted bones

Storey

Feik

1986

Anat. Rec.

View full text Add to dashboard Cite

We divided 116 rats weighing 50 gm into four groups with tails either left in situ or transplanted as follows: straight in situ: untreated controls; bent in situ: five caudal vertebrae (CV) in the loop; straight transplants: three CV skinned and transplanted autologously; and bent transplants: five CV skinned, bent to form a loop, and transplanted autologously. Tails were radiographed weekly up to 6 weeks and at 12 weeks, and microradiographic and histological studies were undertaken on selected specimens. At 12 weeks the bones in the apex of the loop of tails left in situ appeared bent with a straight-to-convex shaft on the outer side and a thicker, more concave one on the inner side. In the transplanted bent segments the bone shaft died and initially the reverse occurred: the outer shaft thickened and the inner resorbed completely. A new concave inner diaphysis then formed so that the bones in both instances were essentially similar in final shape. In the bent transplants the surviving osteogenic tissues regenerated and, adapting to the altered forces, formed a new bone shaft. This involved a change in the direction, amount, and nature of endochondral, periosteal, and regenerative growth and subsequent remodeling of bone. The results support previous observations that, within limits, the strain in the osteogenic envelope is an important factor in adaptation of bones to changing stress and that, where the envelope is deficient, the surviving tissues have the capacity to regenerate and repair defects in the bone so that it best resists the changing stresses applied to it.

show abstract

“…Collagens contain additional tri- and tetravalent cross-links which contain histidine in addition to lysine and lysine-derivatives [13] (Figure 1). In bone tissues, elastin is a component of the periosteum, in which a population of stem cells also occurs [34–38]. The periosteum has been shown to participate in lateral growth of cortical bone, possibly driven by periosteum-derived stem- or progenitor cells.…”

Section: Lysyl Hydroxylase and Lysyl Oxidasementioning

confidence: 99%

Enzymatic and non-enzymatic functions of the lysyl oxidase family in bone

Trackman

2016

Matrix Biology

View full text Add to dashboard Cite

Advances in the understanding of the biological roles of the lysyl oxidase family of enzyme proteins in bone structure and function are reviewed. This family of proteins is well-known as catalyzing the final reaction required for cross-linking of collagens and elastin. Novel emerging roles for these proteins in the phenotypic development of progenitor cells and in angiogenesis are highlighted and which point to enzymatic and non-enzymatic roles for this family in bone development and homeostasis and in disease. The explosion of interest in the lysyl oxidase family in the cancer field highlights the need to have a better understanding of the functions of this protein family in normal and abnormal connective tissue homeostasis at fundamental molecular and cellular levels including in mineralized tissues.

show abstract

Biochemical Identification of Elastin in Periosteum and Pericranium

Cited by 7 publications

References 0 publications

A histological comparison of the repair tissue formed when using either Chondrogide® or periosteum during autologous chondrocyte implantation

A histological comparison of the repair tissue formed when using either Chondrogide® or periosteum during autologous chondrocyte implantation

Remodeling of bone and bones: Effects of altered mechanical stress on the regeneration of transplanted bones

Enzymatic and non-enzymatic functions of the lysyl oxidase family in bone

Contact Info

Product

Resources

About