Biochemical profile of blood in naturally occurring Sarcocystis infection in cattle

Abstract

The aim of this study was to determine the biochemical blood indicators in Lithuanian Black-and-White cattle with regard to the intensity of their infection with Sarcocystis spp. In total 945 bull muscle samples and 120 blood samples were used for the analysis. Aspartate aminotransferase (AST), alkaline phosphatase (ALP), and alanine aminotransferase (ALT) were increased in infected animals relative to uninfected animals. The AST levels differed significantly between the no infection, low, and moderate infection groups (P < 0.05); ALP differed between the no infection and moderate infection groups (P < 0.05); and ALT differed between the no infection, low infection and intense infection groups (P < 0.05). Total protein levels were higher than physiological limits and differed significantly between the no infection, low infection and intense infection groups (P < 0.05). Iron levels were at the lowest physiological limits and differed significantly between the no infection and low infection groups, as well as between the low infection and intense infection groups (P < 0.05). Triglyceride levels were at their physiological limits, and differed significantly between all examined groups (P < 0.05). The results show that changes in the biochemical markers ALP, AST and ALT are related to the intensity of the Sarcocystis spp. infection.

Investigation of Sarcocystis spp. in slaughtered cattle and sheep by peptic digestion and histological examination in Sulaimani Province, Iraq

“…Sarcocystis spp. cyst invasions in the muscle tissue can produce inflammation around the muscle fibers and between the cysts, showing mononuclear cells infiltration (neutrophils, lymphocytes, eosinophils, and plasma cells) and degeneration and necrosis of muscle fibers [25]. Consistently, inflammatory reactions were also detected around some of the observed microsarcocysts in the present study (Figure -4).…”

“…in cattle were also of two types. S. cruzi and S. heydorni have thin-walled cysts, and S. bovini, S. bovifelis, and S. hominis have thick-walled cysts [25].…”

“…Identification of Sarcocystis spp. is not possible using a microscopic analysis [25]. Therefore, the exact identification and differentiation of Sarcocystis spp.…”

“…Slides were examined for the presence of sarcocysts at 10× and further analyzed at 40× and 100×. For the morphological identification Available at www.veterinaryworld.org/Vol.14/February-2021/19.pdf of Sarcocystis spp., the cell wall structure was observed [25].…”

The trend of aetiologies of chronic emaciation in off-take cattle in Ibadan metropolis

“…; chronic inflammations such as endocarditis, lymphadenitis, pleuritis, pericarditis and enteritis etc. (Radostits et al, 2006;Smith, 2008); parasitic infections such as trypanosomiasis, toxoplasmosis, chronic babesiosis (Urquhart et al, 1996;Rajavelu, 2001;Love and Hutchinson, 2003;Khan and Line, 2010;Odeniran and Welburn, 2018;Petersen and Grinnage-Pulley, 2020), anaplasmosis, besnoitiosis, (Bussieras and Chermette, 1991;Khan and Line, 2010), sarcosporidiosis (Urquhart et al, 1996;Bussieras and Chermette, 1991;Januškevičius et al, 2018;More, 2019), and chronic helminthosis (Urquhart et al, 1996;Khan and Line, 2010) etc. ; hepatic and renal conditions associated with several causes (Haroun and Hussein, 1975;Radostits et al, 2006;Smith, 2008); gastrointestinal disorders such as infiltrative diseases (Radostits et al, 2006;Smith, 2008;Wittek, 2014); immune mediated condition associated with amyloid deposition in various organs and hyperglobulinemia, consequent upon chronic infection/inflammation or neoplasm (Radostits et al, 2006); congenital disorders such as congenital cardiac malformations (tetralogy of fallot, interventricular septal defect) and congenital renal disease (agenesis, dysplasia, hypoplasia, polycystic kidney disease) (Smith, 2008) etc., most of which create physiologic inefficiencies that require energy beyond the body's ability to supply it; endocrine dysfunction such as diabetes mellitus (Mostaghni and Ivoghli, 1977); neoplasms such as lymphosarcoma (Bertone, 1990;NADIS, 2011); and primary undernutrition (Oetzel, 1988;Smith, 2008) etc.…”