Biochemical Properties and Cosmetic Uses of Commiphora myrrha and Boswellia serrata

Alraddadi, Bssmah Ghazi; Shin, Hyun‐Jae

doi:10.3390/cosmetics9060119

Cited by 8 publications

(3 citation statements)

References 95 publications

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“…Due to the great medicinal importance of this plant. In this work, we will discover its effect on aortic atherosclerosis [9,10].…”

Section: Introductionmentioning

confidence: 99%

Effect liposome Nanoparticles Loaded with Natural Products Isolated From Commiphora myrrh on Plasminogen Activator Inhibitor-1 in Mice Induced Aortic Atherosclerosis

Yahya,

Bahry Hassin Al-Sadoon

2024

Egyptian Journal of Veterinary Sciences

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HE study included the separation and diagnosis of various natural products from the Myrrh plant, where the oily substance and its fatty acids were separated, which were identified by applying capillary column gas chromatography (CGC) technology. Some flavonoids and alkaloids were also separated. The flavonoids were identified by applying high-performance liquid chromatography (HPLC) technology. The effect of these products on plasminogen activator inhibitor-1 (PAI-1) was studied and it was found that they had a positive effect in reducing the level of PAI-1 and some other measured variables. In addition, the study examined the effect of these natural products on some biochemical parameters related to aortic stiffness in the blood serum of mice induced with the disease. Biochemical variables included: low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), total cholesterol (TC), triglycerides (TG), interleukin 6 (IL-6), and... Tumor necrosis alpha (TNF-alpha). The results showed that the concentrations of PAI-1, IL-6, LDL, TG, TC, and TNF-α increased significantly in infected mice, compared to healthy mice, and a significant decrease in the concentration of HDL was observed. Liposome nanoparticles (LNPs) were prepared from natural products of myrrh plant and characterized using field emission scanning electron microscopy (FE-SEM). Nanoparticles loaded with natural products showed a positive therapeutic effect in mice in which the disease was established through tissue sections of experimental animals.

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“…Due to the great medicinal importance of this plant. In this work, we will discover its effect on aortic atherosclerosis [9,10].…”

Section: Introductionmentioning

confidence: 99%

Effect liposome Nanoparticles Loaded with Natural Products Isolated From Commiphora myrrh on Plasminogen Activator Inhibitor-1 in Mice Induced Aortic Atherosclerosis

Yahya,

Bahry Hassin Al-Sadoon

2024

Egyptian Journal of Veterinary Sciences

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“…Frankincense, also called Boswellia serrata resin or olibanum, is a traditional medicine widely explored in India, China and the Arabian world 1 . The therapeutic potential of frankincense has been widely recognized, and especially in anti‐inflammation, 2 antiseptic, 3 neurotic modulation, 4 and anti‐tumor applications 5 .…”

Section: Introductionmentioning

confidence: 99%

“…

Frankincense, also called Boswellia serrata resin or olibanum, is a traditional medicine widely explored in India, China and the Arabian world. 1 The therapeutic potential of frankincense has been widely recognized, and especially in anti-inflammation, 2 antiseptic, 3 neurotic modulation, 4 and anti-tumor applications. 5 The active ingredients of frankincense from different extraction procedures contain gums and resins with large molecular weight, as well as small functional molecules such as flavonoids, alkaloids, tannins, glycosides,

…”

mentioning

confidence: 99%

Potent pigmentation inhibitory activity of incensole‐enriched frankincense volatile oil‐identification, efficacy and mechanism

Yan

Dai

et al. 2023

J of Cosmetic Dermatology

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BackgroundFrankincense volatile oil (FVO) has long been considered a side product in pharmaceutical industry since frankincense of large molecular weight is the prime target. However, the volatile oil recycled in the extract process might contain a series of functional actives, serving as promising ingredients in the cosmetic field.MethodsGas chromatography‐mass spectrometer was utilized to determine the species and amount of active ingredients in FVO. Subsequently, zebrafish models were used to evaluate pigmentation inhibition, ROS elimination and neutrophil activation. In vitro DPPH test was also conducted to consolidate the anti‐oxidation efficacy. Based on the test results, network pharmacology was incorporated, where GO and KEGG enrichment analyses were performed to discover the interrelations between active ingredients.ResultsAbout 40 actives molecules were identified, including incensole, acetate incensole, and acetate incensole oxide. The FVO demonstrated great depigmentation activity by suppressing melanin synthesis, as well as providing free radical scavenging and anti‐inflammation effect. In network pharmacology analysis, 192 intersected targets were identified. By enrichment analysis and network construction, a series of whitening signal pathways, and hub genes, containing STAT3，MAPK3，MAPK1 were identified.ConclusionThe current study quantified the components of FVO, evaluated its efficacy in skin depigmentation, and give pioneering insights on the possible mechanism. The results confirmed that the FVO could serve as whitening agent in topical uses.

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Boswellia serrata Powder Regimen Provides Significant Protection Against Renal Damage and Blood Imbalances in Diabetic Rats

Kherouf,

Aouacheri

et al. 2024

Chemistry & Biodiversity

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Diabetic kidney disease affects approximately one‐third of diabetes patients. Hyperglycemia and oxidative stress contribute to this condition. Boswellia serrata gum resin is known for its antioxidant properties and potential in managing diabetic complications, though its nephroprotective effects are not well documented. This research aimed to determine the phytochemical constituents of B. serrata using LC‐MS analysis and explore its benefits in enhancing hematological markers and improving STZ‐induced renal dysfunction in rats. Diabetes was induced by a single dose of streptozotocin (60 mg/kg). 40 male albino Wistar rats were divided into four groups: normal control, control with B. serrata (2% w/w), and two diabetic groups. One diabetic group served as a positive control, while the other received B. serrata powder (2% w/w). Results showed that the powder reduced blood sugar, decreased renal markers, increased albumin, total protein and restored hematological parameters. It also enhanced β cell function (HOMA‐β) and prevented kidney structural abnormalities. Additionally, B. serrata reduced oxidative stress by lowering malondialdehyde (MDA) and increasing glutathione (GSH), glutathione‐S‐transferase (GST), catalase (CAT), and glutathione peroxidase (GPx) in renal tissues. LC‐MS identified 37 phenolic compounds, with apigetrin being the most abundant. These findings suggest that B. serrata holds promise for managing diabetes‐related kidney injury.

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Biochemical Properties and Cosmetic Uses of Commiphora myrrha and Boswellia serrata

Cited by 8 publications

References 95 publications

Effect liposome Nanoparticles Loaded with Natural Products Isolated From Commiphora myrrh on Plasminogen Activator Inhibitor-1 in Mice Induced Aortic Atherosclerosis

Effect liposome Nanoparticles Loaded with Natural Products Isolated From Commiphora myrrh on Plasminogen Activator Inhibitor-1 in Mice Induced Aortic Atherosclerosis

Potent pigmentation inhibitory activity of incensole‐enriched frankincense volatile oil‐identification, efficacy and mechanism

Boswellia serrata Powder Regimen Provides Significant Protection Against Renal Damage and Blood Imbalances in Diabetic Rats

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