Biocompatibility

Elshahawy, Waleed

doi:10.5772/18475

Cited by 23 publications

(15 citation statements)

References 39 publications

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“…This phenomenon is responsible for cytotoxicity to a greater or lesser degree. In our experiment, the two main inorganic elements that are potentially released by LS 2 and ZLS are alumina and silicon, both of which are considered to have low cytotoxicity [65,66]. Some studies also blame this low viability on Zn, an LS 2 component considered by some as a cellular-viability suppressor or cytotoxicity increaser [24].…”

Section: Discussionmentioning

confidence: 99%

Biocompatibility of Polymer and Ceramic CAD/CAM Materials with Human Gingival Fibroblasts (HGFs)

et al. 2019

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Four polymer and ceramic computer-aided design/computer-aided manufacturing (CAD/CAM) materials from different manufacturers (VITA CAD-Temp (polymethyl methacrylate, PMMA), Celtra Duo (zirconia-reinforced lithium silicate ceramic, ZLS), IPS e.max CAD (lithium disilicate (LS2)), and VITA YZ (yttrium-tetragonal zirconia polycrystal, Y-TZP)) were tested to evaluate the cytotoxic effects and collagen type I secretions on human gingival fibroblasts (HGFs). A total of 160 disc-shaped samples (Ø: 10 ± 2 mm; h: 2 mm) were milled from commercial blanks and blocks. Direct-contact cytotoxicity assays were evaluated at 24, 48, and 72 h, and collagen type I (COL1) secretions were analysed by cell-based ELISA at 24 and 72 h. Both experiments revealed statistically significant differences (p < 0.05). At 24 and 48 h of contact, cytotoxic potential was observed for all materials. Later, at 72 h, all groups reached biologically acceptable levels. LS2 showed the best results regarding cell viability and collagen secretion in all of the time evaluations, while Y-TZP and ZLS revealed intermediate results, and PMMA exhibited the lowest values in both experiments. At 72 h, all groups showed sharp decreases in COL1 secretion regarding the 24-h values. According to the results obtained and the limitations of the present in vitro study, it may be concluded that the ceramic materials revealed a better cell response than the polymers. Nevertheless, further studies are needed to consolidate these findings and thus extrapolate the results into clinical practice.

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Section: Discussionmentioning

confidence: 99%

Biocompatibility of Polymer and Ceramic CAD/CAM Materials with Human Gingival Fibroblasts (HGFs)

et al. 2019

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“…In order to extend the scope of the new methodology of covering surfaces by primary PDA coating followed by ROP of lactide to PLA, we investigated aluminum oxide, titanium dioxide, and titanium (Scheme 3 ), i.e., materials which are relevant in medicine as joint replacements. [24][25][26][27] Pleasingly, the methodology worked well in these cases too as can be seen in the FTIR spectra (Figure 8 (surface is coated with TiO 2 due to easy oxidation of Ti) ( Figure S11, Supporting Information) coated with PDA and PLA reveal about 46%, 25%, and 29% of organic material, respectively. Particles TiO 2 /PDA/PLA and Ti/PDA/PLA have the same surface material (TiO 2 ).…”

Section: Resultsmentioning

confidence: 74%

Polydopamine – A Versatile Coating for Surface‐Initiated Ring‐Opening Polymerization of Lactide to Polylactide

Mrówczyński

Nan

Turcu

et al. 2014

Macro Chemistry & Physics

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An effi cient way for covering various surfaces with poly(lactic acid) (PLA) is discussed. In a fi rst step, the material is coated with polydopamine (PDA) by air oxidation of dopamine. The resulting PDA layer acts as an initiator for ring-opening polymerization (ROP) of lactide resulting in an outer PLA shell. Since PDA sticks to almost every solid material, the methodology has a wide scope. The strategy is demonstrated with magnetic nanoparticles and non-magnetic powders.can be achieved by ring-opening polymerization (ROP) of lactide in the presence of the material to be covered. There are materials where PLA does not stick or the adhesion is not strong enough. In such cases, a primary adhesive coating is advised that anchors to the material to be covered on the one hand and binds the PLA on the other hand. The most effi cient linkage of PLA is achieved when covalent bonds are formed by surface-initiated ROP. Here, nucleophilic reactive groups at the surface initiate the ROP and fi x the growing PLA chain covalently. In this way, magnetite NPs (MNPs) stabilized by glycolic acid were treated with lactide in the presence of tin(II) 2-ethylhexanoate under microwave conditions. [ 13 ] In a similar manner, MNPs covered with oleic acid underwent a ligand exchange by ω-hydroxy carboxylic acids and were subsequently covered with PLA by tin dioctanoatecatalyzed ROP of L -lactide. [ 14 ] In both cases, the PLA shell anchors by the help of the carboxylate groups of the initial ω-hydroxycarboxylic acid. Since anchoring of carboxylate to magnetite is not very strong and thus reversible, the search for better primary coverage of MNPs is still desired. Furthermore, the application of poisonous tin dioctanoate causes limitations if biomedical applications are considered. In an alternative approach, MNPs were stabilized by glyceryl phosphate or ascorbyl phosphate and then treated with lactide in the presence of 4-( N , N -dimethylamino)pyridine (DMAP). [ 15 ]

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“…A Biomaterial can adapt itself to the chemical reaction in the human body [71,72]. Smart Biomaterials especially shape memory alloys can be used inside the human body as implants, which have two main superior behaviors including bio functionality and biocompatibility [73][74][75].…”

Section: Biocompatibilitymentioning

confidence: 99%

A Review on NiTiCu Shape Memory Alloys: Manufacturing and Characterizations

QADIR

Mohammed

Kök

et al. 2021

Journal of Physical Chemistry and Functional Materials

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ARTICLE INFOShape memory alloys have the thermoelastic phase transformation, known as shape memory characteristics, which make them be used in wide technological applications compared to other alloys. Ni-Ti based SMAs compared to the other families have more applications especially in the biomedical field since they have high biocompatibility, high strain recovery, flexibility, and antirust. In this work, the studies conducted for NiTiCu SMAs were reviewed. Additionally, different manufacturing techniques used by researchers have been explained. Different characteristics of the alloys have been clarified and compared with some other families.

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Biocompatibility

Cited by 23 publications

References 39 publications

Biocompatibility of Polymer and Ceramic CAD/CAM Materials with Human Gingival Fibroblasts (HGFs)

Biocompatibility of Polymer and Ceramic CAD/CAM Materials with Human Gingival Fibroblasts (HGFs)

Polydopamine – A Versatile Coating for Surface‐Initiated Ring‐Opening Polymerization of Lactide to Polylactide

A Review on NiTiCu Shape Memory Alloys: Manufacturing and Characterizations

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