Biocompatibility and functionality of dental restorative materials

Zabrovsky, Asher; Beyth, Nurit; Pietrokovski, Yoav; Ben‐Gal, Gilad; Houri‐Haddad, Yael

doi:10.1016/b978-0-08-100884-3.00005-9

Cited by 10 publications

(16 citation statements)

References 69 publications

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“…The reasons for degradation could be chewing forces, microorganisms, temperature changes, enzymes or saliva. 20 Mastication: While functioning, resin-based restorative materials are exposed to mechanical stress constantly. This situation results in wear on restoration surface and the release of components from the material.…”

Section: Long-term Monomer Release Of Resin-based Restorative Materialsmentioning

confidence: 99%

“…This situation results in wear on restoration surface and the release of components from the material. 20 Saliva: The main ingredient of the saliva is water. Since dental resins are polar molecules, water molecules easily penetrate the polymer network and ease the release of unreacted monomers.…”

Section: Long-term Monomer Release Of Resin-based Restorative Materialsmentioning

confidence: 99%

“…21 In addition saliva, pH can vary from alkaline to acid and may cause chemical deterioration to dental restorations. 20 Microorganisms: Lactic acid produced by bacterias promotes the hydrolisis of the restoration. In addition, oral biofilm formation may also cause degradation, thus revealing different components from the restora-tion.…”

Section: Long-term Monomer Release Of Resin-based Restorative Materialsmentioning

confidence: 99%

“…In addition, oral biofilm formation may also cause degradation, thus revealing different components from the restora-tion. 20,22 Enzymes: Some form of enzymes that are present in saliva and dentinal fluid are responsible for the breakdown of the linkages. The endopeptidases comprise matrix metalloproteinases and cysteine cathepsins are capable of hydrolytic degradation of hybrid layer.…”

Section: Long-term Monomer Release Of Resin-based Restorative Materialsmentioning

confidence: 99%

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Biocompatibility Evaluation of Resin-Based Restorative Materials: A Review

Çimen

Özalp

2021

EADS

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Biocompatibility is described as an appropriate biological response of a biomaterial in a living organism. It is known that biomaterials are not inert and the materials should be tested before they are allowed to be used in clinical practice. Various test methods have been developed and protocols have been determined for this purpose. Resin-based restorative materials are extensively used in dentistry due to the increased aesthetic demands of patients and the ease of use in clinical practice. As the restorative materials function in the mouth for long years, concerns regarding the biocompatibility of resin-based restorative materials become more important. Regarding the importance of this issue, the purpose of this review is to evaluate the local and systemic potential toxicity of resin-based restorative materials, toxicity test methods, and the mechanism of the cytotoxicity in living tissues.

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Section: Long-term Monomer Release Of Resin-based Restorative Materialsmentioning

confidence: 99%

Section: Long-term Monomer Release Of Resin-based Restorative Materialsmentioning

confidence: 99%

Section: Long-term Monomer Release Of Resin-based Restorative Materialsmentioning

confidence: 99%

Section: Long-term Monomer Release Of Resin-based Restorative Materialsmentioning

confidence: 99%

See 2 more Smart Citations

Biocompatibility Evaluation of Resin-Based Restorative Materials: A Review

Çimen

Özalp

2021

EADS

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“…In the case of scaffolds for tooth regeneration, biomaterials are subjected to the challenging environment of the oral cavity-including mechanical forces due to mastication, the presence of microorganisms, and varying conditions regarding temperature and pH. The intended biomaterial has to face these challenges without limitations in its biocompatibility [125]. Since it is generally intended to mimic the native extracellular matrix by using biomaterials, properties besides biocompatibility are imposed by the tissue which should be regenerated.…”

Section: Scaffolds For Enamel Dentin and Cementum Regenerationmentioning

confidence: 99%

Tooth Formation: Are the Hardest Tissues of Human Body Hard to Regenerate?

Baranova

Büchner

Götz

et al. 2020

IJMS

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With increasing life expectancy, demands for dental tissue and whole-tooth regeneration are becoming more significant. Despite great progress in medicine, including regenerative therapies, the complex structure of dental tissues introduces several challenges to the field of regenerative dentistry. Interdisciplinary efforts from cellular biologists, material scientists, and clinical odontologists are being made to establish strategies and find the solutions for dental tissue regeneration and/or whole-tooth regeneration. In recent years, many significant discoveries were done regarding signaling pathways and factors shaping calcified tissue genesis, including those of tooth. Novel biocompatible scaffolds and polymer-based drug release systems are under development and may soon result in clinically applicable biomaterials with the potential to modulate signaling cascades involved in dental tissue genesis and regeneration. Approaches for whole-tooth regeneration utilizing adult stem cells, induced pluripotent stem cells, or tooth germ cells transplantation are emerging as promising alternatives to overcome existing in vitro tissue generation hurdles. In this interdisciplinary review, most recent advances in cellular signaling guiding dental tissue genesis, novel functionalized scaffolds and drug release material, various odontogenic cell sources, and methods for tooth regeneration are discussed thus providing a multi-faceted, up-to-date, and illustrative overview on the tooth regeneration matter, alongside hints for future directions in the challenging field of regenerative dentistry.

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Recent advances in glass‐ceramics: Performance and toughening mechanisms in restorative dentistry

Liu,

Yao,

Zhang

et al. 2023

J Biomed Mater Res

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The use of glass‐ceramics in the medical field has grown significantly since the 1980s. With excellent aesthetic properties, semi‐translucency, outstanding mechanical properties, corrosion resistance, wear resistance and great biocompatibility and workability glass‐ceramics is one of the most commonly used materials in restorative dentistry and is widely used in veneers, inlays, onlays, all‐ceramic crowns, and implant abutments. This review provides an overview of the research progress of glass‐ceramics in restorative dentistry, focusing on the classification, performance requirements, toughening mechanisms and their association with clinical performance, as well as the manufacturing and fabrication of glass‐ceramics in restorative dentistry. Finally, the developments and prospects of glass‐ceramics in restorative dentistry are summarized and discussed.

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Biocompatibility and functionality of dental restorative materials

Cited by 10 publications

References 69 publications

Biocompatibility Evaluation of Resin-Based Restorative Materials: A Review

Biocompatibility Evaluation of Resin-Based Restorative Materials: A Review

Tooth Formation: Are the Hardest Tissues of Human Body Hard to Regenerate?

Recent advances in glass‐ceramics: Performance and toughening mechanisms in restorative dentistry

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