Biocompatible amphiphilic hyperbranched nanocapsules with a functional core: Synergistic encapsulation and asynchronous release properties towards multi-guest molecules

Synthesis and encapsulation of an amphiphilic thermoresponsive star polymer with β-cyclodextrin and hyperbranched poly(oligo(ethylene glycol)methacrylate) as building blocks

“…However, previous reports have demonstrated that micelles can also be formed by direct dissolved amphiphilic polymers in water. 58,59 Fig. 5 1 H NMR spectrum of PE-CD-POEGMAS (P 2 ).…”

“…To further investigate the encapsulation capacity and mechanism of PE-CD-POEGMAs towards multi-guest molecules, consequently, gradual multi-guest encapsulation experiments were conducted. 58 Rh was rstly added into P 2 solution, and then LL or CR or RB was added with different amount, separately. The results of LL and CR are shown in Fig.…”

“…[51][52][53] Compared with amphiphilic linear polymers, amphiphilic nonlinear polymers such as dendrimers, star polymers, and hyperbranched polymers with branched architectures can stably exist as unimolecular micelles or multimolecular micelles in aqueous solution because of their unique chemical structures, and their encapsulation behaviors have been studied and mainly focused on single guest encapsulation. [54][55][56][57] Most recently, the encapsulation phenomena of multi-guest molecules using amphiphilic hyperbranched polymers was reported by Tian et al 58 However, there are still few attentions and researches on encapsulation of amphiphilic thermal responsive star polymer with CDs and hyperbranched POEGMAs as building blocks for multi-guest molecules.…”

Pseudo-graft polymer based on adamantyl-terminated poly(oligo(ethylene glycol) methacrylate) and homopolymer with cyclodextrin as pendant: its thermoresponsivity through polymeric self-assembly and host–guest inclusion complexation

“…A variety of subtle noncovalent interactions such as hydrogen bonding, metal-ligand coordination interaction, electrostatic attraction, and hostguest inclusion complexation have been widely used as driving forces for constructing supramolecular systems. [24][25][26][27][28][29][30][31][32][33][34] Therefore, on the basis of these results, well-dened Ad-POEGMAs are synthesized in this study for the rst time and are used to netune the LCSTs of PEG-based thermoresponsive polymers. Moreover, this work focuses on the self-assembly behavior of a composite system between Ad-POEGMAs as guests consisting of POEGMAs as thermal blocks and PGCD as multi-host with pendant CD cavities via inclusion complexation.…”

Kinetic topology‐selective encapsulation and mixture separation by a nanocapsule with hyperbranched polyethylenimine as core and polystyrene as shell

“…The core–shell amphiphilic macromolecules (CAM) derived from hyperbranched polymers have attracted a lot of interest in the supramolecular encapsulation fields . The popularity of CAMs is mainly related to a hyperbranched polymer's cost‐effective production, multifunctionality, wide structural spectrum, and 3D morphology, and CAMs are widely used as a supramolecular host for a variety of small‐guest molecules in supramolecular encapsulations . The supramolecular encapsulation can be applied to solubilization, delivery and controlled release, and enrichment and separation .…”