Biocompatible Bright YVO<sub>4</sub>:Eu Nanoparticles as Versatile Optical Bioprobes

Shen, Jie; Sun, Ling‐Dong; Zhu, Jingshuai; Wei, Liuhe; Sun, Hai; Yan, Chun‐Hua

doi:10.1002/adfm.201001264

Cited by 157 publications

(106 citation statements)

References 37 publications

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“…See DOI: 10.1039/c3dt50676b a Instituto de Ciencia de Materiales de Sevilla, CSIC-US, Americo Vespucio 49, 41092, Isla de la Cartuja, Sevilla, Spain. E-mail: nurianu@icmse.csic.es b molecules of biological interest is an important issue since they provide anchors for adding functional ligands such as antibodies and drugs 16 and affect the colloidal stability of nanoparticles suspensions as recently demonstrated for YVO 4 : Eu nanoparticles, 17 which are isostructural to those herein studied. However, among the above-mentioned reports dealing with Ln:GdVO 4 nanoparticles, only that by Kang et al was conducted using poly(acrylic) acid functionalized GdVO 4 spheres, which were above the nanometric size range (180 nm) and showed a rather irregular shape and a certain degree of aggregation.…”

Section: Nanocrystals)mentioning

confidence: 78%

Surface modified Eu:GdVO4 nanocrystals for optical and MRI imaging

et al. 2013

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A facile solvothermal route has been developed for the preparation of europium doped gadolinium orthovanadate nanoparticles (∼70 nm) with tetragonal structure, based on a homogenous precipitation reaction at 120°C from rare earth precursors (yttrium nitrate and europium nitrate) and sodium orthovanadate solutions using an ethylene glycol-water mixture as the solvent. The effects of the doping level on the luminescence properties were evaluated in order to find the optimum nanophosphors. These nanocrystals were successfully functionalized with amino (two step process) and carboxylate (one-pot process) groups provided by amino-dextran polymers (AMD) and polyacrylic acid (PAA), respectively. It was found that while the luminescent properties of both kinds of functionalized systems were similar, the colloidal stability of the PAA-modified sample was higher, because of which, it was selected to study their cytotoxicity and magnetic properties (relaxivity and phantom analyses) to assess their potentiality as multifunctional probes for both "in vitro" optical biolabels and negative contrast agents for magnetic resonance imaging.

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Section: Nanocrystals)mentioning

confidence: 78%

Surface modified Eu:GdVO4 nanocrystals for optical and MRI imaging

et al. 2013

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“…Eu(III)-doped YVO 4 NPs are typical red emission materials for cell immunoassay. Yan group used a vanadate fluorescent marker for the preliminary cell image tests [185]. YVO 4 :Eu NPs were synthesized via a one-pot hydrothermal reaction and biotinated.…”

Section: In Vitro and In Vivo Imagingmentioning

confidence: 99%

Fluorescent nanoparticles for chemical and biological sensing

Liu

Yang

et al. 2011

Sci. China Chem.

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Fluorescent nanoparticles (NPs), including quantum dots (QDs), dye-doped NPs, and rare earth-based NPs, etc., have been a major focus of research and development during the past decade. The impetus behind such endeavors can be attributed to their unique chemical and optical properties, such as bright fluorescence, high photostability, large Stocks shift and flexible processability. The introduction of fluorescent NPs into analytical chemistry has opened up new venues for fluorescent analysis. In this review, we focus on the developments and analytical applications of fluorescent NPs in the chemical and biological sensing of pH, ions, organic compounds, small biological molecules, nucleic acids, proteins, virus and bacteria. The review also points out the in vitro and in vivo imaging application of fluorescent NPs at the cell and body levels. Meanwhile, the advantages of NPs brought field of sensing and signal transductions are also discussed. fluorescence, sensing, quantum dots, dye-doped nanoparticles, rare earth-based nanoparticles

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“…Notably, rare-earth vanadates are a promising class of rare-earth compounds with wonderful characteristics, such as bright fluorescence and chemical and thermal stability [42,43]. However, the classical crystallization kinetics process often results in rapid nucleation and growth, which cause the direct shell formation to be unfavorable.…”

Section: Anion Exchange To Transform the Oxide Shell Into Vanadatementioning

confidence: 99%

Synthesis of gold/rare-earth-vanadate core/shell nanorods for integrating plasmon resonance and fluorescence

et al. 2015

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The nanoscale core/shell heterostructure is a particularly efficient motif to combine the promising properties of plasmonic materials and rare-earth compounds; however, there remain significant challenges in the synthetic control due to the large interfacial energy between these two intrinsically unmatched materials. Herein, we report a synthetic route to grow rare-earth-vanadate shells on gold nanorod (AuNR) cores. After modifying the AuNR surface with oleate through a surfactant exchange, well-packaged rare-earth oxide (e.g., Gd 2 O 3 : Eu) shells are grown on AuNRs as a result of the multiple roles of oleate. Furthermore, the composition of the shell has been altered from oxide to vanadate (GdVO 4 : Eu) using an anion exchange method. Owing to the carefully designed strategy, the AuNR cores maintain the morphology during the synthesis process; thus, the final Au/GdVO 4 : Eu core/shell NRs exhibit strong absorption bands and high photothermal efficiency. In addition, the Au/GdVO 4 : Eu NRs exhibit bright Eu 3+ fluorescence with quantum yield as high as ~17%; bright Sm 3+ and Dy 3+ fluorescence can also be obtained by changing the lanthanide doping in the oxide formation. Owing to the attractive integration of the plasmonic and fluorescence properties, such core/shell heterostructures will find particular applications in a wide array of areas, from biomedicine to energy.

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Biocompatible Bright YVO₄:Eu Nanoparticles as Versatile Optical Bioprobes

Cited by 157 publications

References 37 publications

Surface modified Eu:GdVO4 nanocrystals for optical and MRI imaging

Surface modified Eu:GdVO4 nanocrystals for optical and MRI imaging

Fluorescent nanoparticles for chemical and biological sensing

Synthesis of gold/rare-earth-vanadate core/shell nanorods for integrating plasmon resonance and fluorescence

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Biocompatible Bright YVO4:Eu Nanoparticles as Versatile Optical Bioprobes

Cited by 157 publications

References 37 publications

Surface modified Eu:GdVO4 nanocrystals for optical and MRI imaging

Surface modified Eu:GdVO4 nanocrystals for optical and MRI imaging

Fluorescent nanoparticles for chemical and biological sensing

Synthesis of gold/rare-earth-vanadate core/shell nanorods for integrating plasmon resonance and fluorescence

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Biocompatible Bright YVO₄:Eu Nanoparticles as Versatile Optical Bioprobes