Bioconversion of Whey Lactose into Microbial Exopolysaccharides

Lo, Y. Martin; Argın, Sanem; Hsu, Chia-Hua

doi:10.1016/b978-044452114-9/50023-2

Cited by 13 publications

(7 citation statements)

References 109 publications

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“…These results were in agreement with that obtained by Abbas and Osman (1998) Salama (2002) and Badran et al (2004) who reported that the TA increased gradually during storage period. The majority of EPS-producing microorganisms utilize carbohydrates as their energy source as well as their carbon source for EPS formation, but the non-EPS-producing starter cultures utilize carbohydrates as their energy source as well as their carbon source for lactic acids and volatile production formation (Lo et al, 2007).…”

Section: Resultsmentioning

confidence: 99%

Effects of exopolysaccharide-producing starter cultures on physicochemical, rheological and sensory properties of fermented camel and #8217;s milk

Ibrahim

2015

Emir. J. Food Agric

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The aim of this study was to examine the influence of using exopolysaccharide (EPS) producing starter cultures on physicochemical, rheological and sensory properties of fermented camel milk. Four starter cultures of the strains of non-EPS and EPS-producing were combined and distribution in four treatments portions to made yoghurt from camel's milk. Results showed that the maximum acetaldehyde and diacetyl contents were found in control treatment during 7 days storage period. The EPS concentration was detected between 41.3 to 269.3 mg/kg in the yoghurt made with non-EPS and EPS-producing starter cultures. The highest EPS concentration was observed in treatment C (1.5% EPS-producing Streptococcus thermophilus plus 1.5% non EPS-producing Lb. delbrueckii ssp. bulgaricus) during 14 days storage period, then reduced at the end of the storage period. Yoghurt made with any EPS-producing strains had significantly (P<0.05) lower firmness, syneresis and higher viscosity values than control yoghurt. Overall acceptability scores of the sensory evaluation revealed that the yoghurt made with EPS-producing starter cultures in treatment C was the most accepted, while the control treatment was the least. According to the results, exopolysaccharide enhance viscosity, texture and mouthfeel and to avoid syneresis in yoghurt. The results of this study suggest that the use of EPS-producing cultures could provide better textures for camel milk yoghurt than those imparted by additives.

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Section: Resultsmentioning

confidence: 99%

Effects of exopolysaccharide-producing starter cultures on physicochemical, rheological and sensory properties of fermented camel and #8217;s milk

Ibrahim

2015

Emir. J. Food Agric

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“…However, a critical review of existing literature shows significant variations in the effect of higher nitrogen concentrations on EPS yield. Some previous reports showed that higher nitrogen presented unfavorable effects on the EPS yield by P. acidipropionici and on the other hand, favorable effects on EPS production by S. thermophilus [42].…”

Section: Effect Of Ammonium Sulfate Concentrationmentioning

confidence: 88%

“…These observations suggested that the effect of nitrogen on EPS yield is microbe microbe-specific and that there is a need to determine the ideal nitrogen concentration for enhanced EPS yield on a 'case by case' basis [42].…”

Section: Effect Of Ammonium Sulfate Concentrationmentioning

confidence: 99%

Optimization of Exopolysaccharide (EPS) Production by Rhodotorula mucilaginosa sp. GUMS16

et al. 2021

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Exopolysaccharides (EPSs) are important biopolymers with diverse applications such as gelling compounds in food and cosmetic industries and as bio-flocculants in pollution remediation and bioplastics production. This research focuses on enhancing crude EPS production from Rhodotorula mucilaginosa sp. GUMS16 using the central composite design method in which five levels of process variables of sucrose, pH, and ammonium sulfate were investigated with sucrose and ammonium sulfate serving as carbon and nitrogen sources during microbial incubation. The optimal crude EPS production of 13.48 g/100 mL was achieved at 1 g/100 mL of sucrose concentration, 14.73 g/100 mL of ammonium sulfate at pH 5. Variations in ammonium sulfate concentrations (1.27–14.73 g/100 mL) presented the most significant effects on the crude EPS yield, while changes in sucrose concentrations (1–5 g/100 mL) constituted the least important process variable influencing the EPS yield. The Rhodotorula mucilaginosa sp. GUMS16 may have the potential for large-scale production of EPS for food and biomedical applications.

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“…To increase the drug targeting effect to the brain, the authors used an o/w nanoemulgel system that contains oleic acid/labrasol in a ratio of 1:5 and xanthan gum, a mucoadhesive polymer. Xanthan gum is a high molecular weight anionic hydrophilic polymer and acts as a thickener and stabilizer of emulsions or suspensions due to its excellent heat and pH tolerability [166]. The particle size was between 45-146 nm and had high bioadhesion strength (0.142N) to the bovine nasal mucosa.…”

Section: Therapeutic Applications Of Nose-to-brain Delivery 81 Epilepsymentioning

confidence: 99%

Nanotherapeutics for Nose-to-Brain Drug Delivery: An Approach to Bypass the Blood Brain Barrier

2021

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Treatment of neurodegenerative diseases or other central nervous system (CNS) disorders has always been a significant challenge. The nature of the blood-brain barrier (BBB) limits the penetration of therapeutic molecules to the brain after oral or parenteral administration, which, in combination with hepatic metabolism and drug elimination and inactivation during its journey in the systemic circulation, decreases the efficacy of the treatment, requires high drug doses and often induces adverse side effects. Nose-to-brain drug delivery allows the direct transport of therapeutic molecules by bypassing the BBB and increases drug concentration in the brain. The present review describes mechanisms of nose-to-brain drug delivery and discusses recent advances in this area with especial emphasis on nanotechnology-based approaches.

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Bioconversion of Whey Lactose into Microbial Exopolysaccharides

Cited by 13 publications

References 109 publications

Effects of exopolysaccharide-producing starter cultures on physicochemical, rheological and sensory properties of fermented camel and #8217;s milk

Effects of exopolysaccharide-producing starter cultures on physicochemical, rheological and sensory properties of fermented camel and #8217;s milk

Optimization of Exopolysaccharide (EPS) Production by Rhodotorula mucilaginosa sp. GUMS16

Nanotherapeutics for Nose-to-Brain Drug Delivery: An Approach to Bypass the Blood Brain Barrier

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