Biodegradation aspects of ibuprofen and identification of ibuprofen-degrading microbiota in an immobilized cell bioreactor

Navrozidou, Efstathia; Melidis, Paraschos; Ntougias, Spyridon

doi:10.1007/s11356-019-04771-5

Cited by 23 publications

(9 citation statements)

References 45 publications

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“…Recently, Navrozidou et al (2019) reported that Novosphingobium was a predominant genus in activated sludge after application of a high dose of ibuprofen. Therefore, this genus is likely to metabolize this PPCP.…”

Section: Impact Of Ppcps On the Composition Of The Bacterial Communitiesmentioning

confidence: 99%

Bacterial ecotoxicity and shifts in bacterial communities associated with the removal of ibuprofen, diclofenac and triclosan in biopurification systems

Aguilar-Romero

Romero

Wittich

et al. 2020

Science of The Total Environment

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The proliferation and possible adverse effects of emerging contaminants such as pharmaceutical and personal care products (PPCPs) in waters and the environment is causing increased concern. We investigated the dissipation of three PPCPs: ibuprofen (IBP), diclofenac (DCF) and triclosan (TCS), separately or in mixture, in the ppm range in microcosm biopurification systems (BPS), paying special attention to their effect on bacterial ecotoxicity and on bacterial community structure and composition. The results reveal that the BPS efficiently dissipates IBP and DCF with 90% removal after 45 and 84 days of incubation, respectively. However, removal of TCS required longer incubation, 127 days for 90% removal. Furthermore, dissipation of the three PPCPs was slower when all three were applied to the BPS as a mixture. TCS had an initial negative effect on bacterial viability by a decrease of 34-43%; however, this effect was mitigated when all three PPCPs were present simultaneously. The bacterial communities in the BPS were affected much more by incubation time than by the applied PPCPs.Nonetheless, the PPCPs affected differentially the composition and relative abundance of bacterial taxa. IBP and DCF initially increased bacterial diversity and richness while exposure to TCS generally provoked the opposite effect. TCS had the largest effect on bacterial groups negatively affecting the relative abundance of Acidobacteria, Rickettsiales, Methylophilales, Methylacidiphilae and Phycisphaerae. On the other hand, all three PPCPs stimulated the dominant bacterial families Promicromonosporaceae, Caulobacteraceae, Xanthomonadaceae, Cyclobacteriaceae, Sphingobacteriaceae and Verrucomicrobiaceae, whose members could harbour mechanisms for resistance by degradation and/or detoxification.

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Section: Impact Of Ppcps On the Composition Of The Bacterial Communitiesmentioning

confidence: 99%

Bacterial ecotoxicity and shifts in bacterial communities associated with the removal of ibuprofen, diclofenac and triclosan in biopurification systems

Aguilar-Romero

Romero

Wittich

et al. 2020

Science of The Total Environment

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“…An analysis of recently published studies ( Table 6 ) [ 81 , 83 , 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 , 92 , 93 , 94 , 95 , 96 ] suggests that the use of consortia of different microorganisms, including microalgae cells, can allow us to resolve the problems of biodegradation of PCPs at a higher level. In particular, the use of natural or artificial cell consortia makes it possible to expand the spectrum of degradable compounds, to carry out effective degradation of PCPs mixtures, to combine the concentration (accumulation) of PCPs and their degradation and to make this degradation thorough.…”

Section: Microbial Consortia For Biodegradation Of Pcpsmentioning

confidence: 99%

“…One of the ways to retain high concentrations of cells constituting consortia in the media with PCPs is their immobilization on different carriers [ 91 , 92 , 93 , 94 , 95 , 96 ]. This makes possible the processing of wastewater in periodic and continuous regimes with the extension of the ranges of applied pH values (from 4 to 9) and temperature (from 20 °C to 45 °C) [ 91 ].…”

Section: Microbial Consortia For Biodegradation Of Pcpsmentioning

confidence: 99%

Progressive Biocatalysts for the Treatment of Aqueous Systems Containing Pharmaceutical Pollutants

Ефременко

Stepanov

Senko

et al. 2023

Life

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The review focuses on the appearance of various pharmaceutical pollutants in various water sources, which dictates the need to use various methods for effective purification and biodegradation of the compounds. The use of various biological catalysts (enzymes and cells) is discussed as one of the progressive approaches to solving problems in this area. Antibiotics, hormones, pharmaceuticals containing halogen, nonsteroidal anti-inflammatory drugs, analgesics and antiepileptic drugs are among the substrates for the biocatalysts in water purification processes that can be carried out. The use of enzymes in soluble and immobilized forms as effective biocatalysts for the biodegradation of various pharmaceutical compounds (PCPs) has been analyzed. Various living cells (bacteria, fungi, microalgae) taken as separate cultures or components of natural or artificial consortia can be involved in biocatalytic processes under aerobic or anaerobic conditions. Cells as biocatalysts introduced into water treatment systems in suspended or immobilized form are used for deep biodegradation of PCPs. The potential of combinations of biocatalysts with physical–chemical methods of wastewater treatment is evaluated in relation to the effective removing of PCPs. The review analyzes recent results and the main current trends in the development of biocatalytic approaches to biodegradation of PCPs, the pros and cons of the processes and the biocatalysts used.

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“…Nitrosomonas europaea is an ammonia-oxidizing bacterium that is frequently associated with the degradation of hormones (e.g., [42]). Studies on the evolution of microbial populations in the presence of 17β-estradiol established a relationship between the presence of some bacteria (Nitrosomonas, Bacillus, Pseudomonas, Sphingomonas, Novosphingobium, Alcaligenes, Rhodanobacter and Mycobacterium) and the biomineralization of the contaminant [147,148]. The complete sequencing of different species of Sphingobium are being carried out to characterize and compare the expression activities of NP-degrader genes [149].…”

Section: Mycoremediationmentioning

confidence: 99%

From Laboratory Tests to the Ecoremedial System: The Importance of Microorganisms in the Recovery of PPCPs-Disturbed Ecosystems

et al. 2020

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The presence of a wide variety of emerging pollutants in natural water resources is an important global water quality challenge. Pharmaceuticals and personal care products (PPCPs) are known as emerging contaminants, widely used by modern society. This objective ensures availability and sustainable management of water and sanitation for all, according to the 2030 Agenda. Wastewater treatment plants (WWTP) do not always mitigate the presence of these emerging contaminants in effluents discharged into the environment, although the removal efficiency of WWTP varies based on the techniques used. This main subject is framed within a broader environmental paradigm, such as the transition to a circular economy. The research and innovation within the WWTP will play a key role in improving the water resource management and its surrounding industrial and natural ecosystems. Even though bioremediation is a green technology, its integration into the bio-economy strategy, which improves the quality of the environment, is surprisingly rare if we compare to other corrective techniques (physical and chemical). This work carries out a bibliographic review, since the beginning of the 21st century, on the biological remediation of some PPCPs, focusing on organisms (or their by-products) used at the scale of laboratory or scale-up. PPCPs have been selected on the basics of their occurrence in water resources. The data reveal that, despite the advantages that are associated with bioremediation, it is not the first option in the case of the recovery of systems contaminated with PPCPs. The results also show that fungi and bacteria are the most frequently studied microorganisms, with the latter being more easily implanted in complex biotechnological systems (78% of bacterial manuscripts vs. 40% fungi). A total of 52 works has been published while using microalgae and only in 7% of them, these organisms were used on a large scale. Special emphasis is made on the advantages that are provided by biotechnological systems in series, as well as on the need for eco-toxicological control that is associated with any process of recovery of contaminated systems.

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Biodegradation aspects of ibuprofen and identification of ibuprofen-degrading microbiota in an immobilized cell bioreactor

Cited by 23 publications

References 45 publications

Bacterial ecotoxicity and shifts in bacterial communities associated with the removal of ibuprofen, diclofenac and triclosan in biopurification systems

Bacterial ecotoxicity and shifts in bacterial communities associated with the removal of ibuprofen, diclofenac and triclosan in biopurification systems

Progressive Biocatalysts for the Treatment of Aqueous Systems Containing Pharmaceutical Pollutants

From Laboratory Tests to the Ecoremedial System: The Importance of Microorganisms in the Recovery of PPCPs-Disturbed Ecosystems

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