Biodisponibilidade e classificação de compostos fenólicos

Arnoso, Bernardo Junqueira de Moraes; Costa, Giselle França Da; Schmidt, Betina

doi:10.33233/nb.v18i1.1432

Cited by 14 publications

(9 citation statements)

References 50 publications

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“…Among bioactive compounds, phenolic compounds can be highlighted, which are molecules containing a phenol group (functional hydroxyl group in aromatic ring) and can have a high antioxidant content. These aromatic molecules act as defense agents to the stresses caused to vegetables and fruits, giving greater astringency, color and flavor to these foods (Arnoso et al, 2019). Phenolics make up a group with widely diversified structures, with more than 8000 molecules currently known, which Research, Society and Development, v. 11, n. 6, e55211629315, 2022 (CC BY 4.0) | ISSN 2525-3409 | DOI: http://dx.doi.org/10.33448/rsd-v11i6.29315 8 can range from simple phenolic molecules, such as gallic acid (Fig.…”

Section: Resultsmentioning

confidence: 99%

Ora-pro-nobis - chemical characterization and sourcing of crude extract through different extraction methods: a review

Carnevalli

Ramos

Mardigan

et al. 2022

RSD

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Ora-pro-nobis has its center of origin in tropical America. It is found in Brazil, from the Northeast to Rio Grande do Sul. The plant belongs to the Cactaceae family, Pereskia genus. Its leaves and fruits contain bioactive compounds that may have expectorant properties and can be used to alleviate inflammatory processes in traditional medicine. Despite its richness, the plant is still little used by the general population and the food and pharmaceutical industries. Some extraction methods are used to obtain bioactive compounds from crude plant extracts, such as maceration, supercritical fluid, and ultrasound-assisted extraction, which have stood out for meeting the principles of green chemistry. The chemical characterization of the extracts obtained through chromatographic analysis by GC-MS/MS and LC-MS/MS proves to be extremely effective, as it allows quantifying the various chemical species present in the extract, making it possible to evaluate and compare the results generated in each chosen extraction condition. The objective of this research is to conduct a review study about the Pereskia aculeata Miller plant. To this end, an exploratory study was carried out, by means of theoretical surveys through Science direct, Capes, Scielo and Pubmed databases. Extracting from plants using different methods is an important step for the industry, ensuring improvement in the quality of products, especially in the food and pharmaceutical sectors. In this sense, no comparative study was found in the literature employing different extraction methods for ora-pro-nobis in the sense of identifying the best method, one with better yield and greater amount of bioactive compounds. The search for different extraction strategies integrated with processes and products that can extract intelligently, minimizing waste, shows an innovative potential in future research.

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Section: Resultsmentioning

confidence: 99%

Ora-pro-nobis - chemical characterization and sourcing of crude extract through different extraction methods: a review

Carnevalli

Ramos

Mardigan

et al. 2022

RSD

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“…Phenolic acids are part of the group of phenolic compounds, rarely occur as free acids, are divided into benzoic, cinnamic acids and their derivatives, p-hydroxybenzoic acid is the simplest form found in nature [23] .…”

Section: Subfractions Xccmentioning

confidence: 99%

Isolation of active antiphytopathogen compound from extracts of Anadenanthera colubrina var. cebil (Griseb.) Altschul

et al. 2022

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Several microorganisms are responsible for great economic losses in world agriculture. Preventive and treatment methods are applied to avoid contamination of crops by these microorganisms, however, the use of chemical antimicrobials damages health and the environment. Secondary plant metabolites are safe natural sources of antimicrobials for this application. Fabaceae family has its history described in the literature as a potential source for obtaining antimicrobial bioactive. The objective of this work was to isolate bioactive compounds guided by antimicrobial assays against bacteria and fungi in vitro. Organic extracts were prepared by eluotropic series of leaves of Anadenanthera colubrina var. cebil and were tested against six bacteria and six fungi phytopathogenic. The antimicrobial assays of minimum inhibitory concentration (MIC) and minimum microbicidal concentration (MMC) were performed at each purification step that occurred through HPLC-DAD, Flash Chromatography and HPLC-preparative analysis, to confirm the isolation of the bioactive. Through bioguided isolation, the compound p-hydroxybenzoic acid was obtained, which showed activity against the phytobacteria Xanthomonas campestris pv. campestris and Acidovorax citrulli.

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“…Research on natural compounds aimed at boosting the host's immunity holds promise for maintaining overall health and improving clinical signs and biochemical markers, with various beneficial properties for humans and animals, including the maintaining of a well-balanced oral microbiota (Mooney et al, 2021). The constant search for preventive health strategies, which help medical treatments and bring quality of life, has led researchers to study phytochemicals, which are abundant in foods such as fruit, vegetables and legumes, as their constant consumption helps fight diseases due to their antioxidant and anti-inflammatory actions, acting as protectors of the body (Arnoso et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Current evidences of therapeutic effects of sulforaphane on oral and intestinal microbiota in Autism Spectrum Disorder – ASD

Damasceno,

Fernandes,

Silva

et al. 2023

CLIUM

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Growing evidence suggests that the Sulforaphane promising agent against oxidative stress related to Autism Spectrum Disorder (ASD), can reduce signs and symptoms like impaired communication and socialization, stereotyped behaviour and neurodevelopmental abnormalities. The oral and intestinal microbiota is extremely important, when out of balance, is one of the main causes of various desordens in the human organism. Broccoli is one of the functional foods most investigated by science. It contains Sulforaphane, an isothiocyanate with great antioxidant and anti-inflammatory capacity; with studies focusing on neurodegenerative and neurodevelopmental diseases. The bibliographic survey was carried out on the Pubmed platform, between 2013 and 2023, in informations provided for Ministério da Saúde – Brasil and in nutrition books. This is a systematic review on Sulforaphane supplementation for people with ASD and its implications for controlling the symptoms that most affect this population, opens a new avenue for managing autistic patients through non-pharmacological intervention.

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Biodisponibilidade e classificação de compostos fenólicos

Cited by 14 publications

References 50 publications

Ora-pro-nobis - chemical characterization and sourcing of crude extract through different extraction methods: a review

Ora-pro-nobis - chemical characterization and sourcing of crude extract through different extraction methods: a review

Isolation of active antiphytopathogen compound from extracts of Anadenanthera colubrina var. cebil (Griseb.) Altschul

Current evidences of therapeutic effects of sulforaphane on oral and intestinal microbiota in Autism Spectrum Disorder – ASD

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