Biofabrication and characterization of cyanobacteria derived ZnO NPs for their bioactivity comparison with commercial chemically synthesized nanoparticles

Asif, Nida; Fatima, Samreen; Aziz, Md. Nafe; Shehzadi,; Zaki, Almaz; Fatma, Tasneem

doi:10.1016/j.bioorg.2021.104999

Cited by 27 publications

(17 citation statements)

References 58 publications

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“…The resulting extracts were centrifuged at 10,000 g for 30 min, filtered through Whatman No. 1 filter paper and stored in refrigerator at 4 °C for further use as cell extract 18 . The chemical profile of cyanobacterial extract was analysed using GC–MS to find out the probable compounds that have reducing potential and aided the synthesis of nanoparticles.…”

Section: Methodsmentioning

confidence: 99%

“…Size distributions of synthesized CuONPs were measured using a Nano Zetasizer system (Zeta sizer, Malvern, UK). Before measuring the sample were passed through a 0.2 μm polyvinylidene fluoride (PVDF) membrane with the parameters used such as measurement temperature (25 °C), medium viscosity, and material refractive index (1.59) 18 . The size of CuONPs was determined by SEM (Carl Zeiss, USA) equipped with EDS, and TEM.…”

Section: Methodsmentioning

confidence: 99%

“…Suspensions of CuONPs were sonicated to avoid NPs agglomeration (details given in ESI Section S1). The absorbance was measured spectrophotometrically against the corresponding blank solutions and the percentage inhibition of free radical scavenging was calculated using following equation 18 . where where Ac = Absorbance of control, At = Absorbance of test.…”

Section: Methodsmentioning

confidence: 99%

“…These are able to synthesize inorganic and metal oxide NPs e.g. selenium, zinc, platinum, palladium, gold, and silver nanoparticles 14 – 18 . Cyanobacteria facilitated synthesis of NPs occurs either through extracellularly, that involves the production of reductase enzyme due to electrostatic interactions and intracellularly i.e.…”

Section: Introductionmentioning

confidence: 99%

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Toxicological assessment of Phormidium sp. derived copper oxide nanoparticles for its biomedical and environmental applications

Asif

Ahmad

Fatima

et al. 2023

Sci Rep

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Driven by the need to biosynthesized alternate biomedical agents to prevent and treat infection, copper oxide nanoparticles (CuONPs) have surfaced as a promising avenue. Cyanobacteria-derived synthesis of CuONPs is of substantive interest as it offers an eco-friendly, cost-effective, and biocompatible route. In the present study biosynthesized CuONPs were characterized and investigated regarding their toxicity. Morphological analysis using TEM, SEM and AFM showed the spherical particle size of 20.7 nm with 96% copper that confirmed the purity of CuONPs. Biogenic CuONPs with IC50 value of 64.6 µg ml−1 showed 90% scavenging of free radicals in superoxide radical scavenging assay. CuONPs showed enhanced anti-inflammatory activity by 86% of protein denaturation with IC50 value of 89.9 µg ml−1. Biogenic CuONPs exhibited significant toxicity against bacterial strains with lowest MIC value of 62.5 µg ml−1 for B. cereus and fungal strain with a MIC value of 125 µg ml−1 for C. albicans. In addition CuONPs demonstrated a high degree of synergistic interaction when combined with standard drugs. CuONPs exhibited significant cytotoxicity against non-small cell lung cancer with an IC50 value of 100.8 µg ml−1 for A549 and 88.3 µg ml−1 for the H1299 cell line with apoptotic activities. Furthermore, biogenic CuONPs was evaluated for their photocatalytic degradation potential against methylene blue dye and were able to removed 94% dye in 90 min. Free radical scavenging analysis suggested that CuONPs assisted dye degradation was mainly induced by hydroxide radicals. Biogenic CuONPs appears as an eco-friendly and cost effective photocatalyst for the treatment of wastewater contaminated with synthetic dyes that poses threat to aquatic biota and human health. The present study highlighted the blend of biomedical and photocatalytic potential of Phormidium derived CuONPs as an attractive approach for future applications in nanomedicine and bioremediation.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Toxicological assessment of Phormidium sp. derived copper oxide nanoparticles for its biomedical and environmental applications

Asif

Ahmad

Fatima

et al. 2023

Sci Rep

Self Cite

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show abstract

“…In the context of nanomaterials, EDX is particularly useful for characterizing the elemental composition of nanoparticles synthesized from natural sources [ 87 ]. The study of Asif et al [ 94 ] investigated the biofabrication and characterization of the cyanobacteria Oscillatoria sp.-derived ZnO-NPs and compared their bioactivity with commercially synthesized NPs. UV-Vis spectroscopy showed an absorption peak of 370 nm for the synthesized NPs.…”

Section: Green Synthesis Of Zno-nps From Micro and Macroalgaementioning

confidence: 99%

Algal Extracts for Green Synthesis of Zinc Oxide Nanoparticles: Promising Approach for Algae Bioremediation

et al. 2023

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Zinc oxide nanoparticles (ZnO-NPs) possess unique properties, making them a popular material across various industries. However, traditional methods of synthesizing ZnO-NPs are associated with environmental and health risks due to the use of harmful chemicals. As a result, the development of eco-friendly manufacturing practices, such as green-synthesis methodologies, has gained momentum. Green synthesis of ZnO-NPs using biological substrates offers several advantages over conventional approaches, such as cost-effectiveness, simplicity of scaling up, and reduced environmental impact. While both dried dead and living biomasses can be used for synthesis, the extracellular mode is more commonly employed. Although several biological substrates have been successfully utilized for the green production of ZnO-NPs, large-scale production remains challenging due to the complexity of biological extracts. In addition, ZnO-NPs have significant potential for photocatalysis and adsorption in the remediation of industrial effluents. The ease of use, efficacy, quick oxidation, cost-effectiveness, and reduced synthesis of harmful byproducts make them a promising tool in this field. This review aims to describe the different biological substrate sources and technologies used in the green synthesis of ZnO-NPs and their impact on properties. Traditional synthesis methods using harmful chemicals limit their clinical field of use. However, the emergence of algae as a promising substrate for creating safe, biocompatible, non-toxic, economic, and ecological synthesis techniques is gaining momentum. Future research is required to explore the potential of other algae species for biogenic synthesis. Moreover, this review focuses on how green synthesis of ZnO-NPs using biological substrates offers a viable alternative to traditional methods. Moreover, the use of these nanoparticles for industrial-effluent remediation is a promising field for future research.

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A review on biological synthesis of ZnO nanostructures and its application in photocatalysis mediated dye degradation: An overview

Areeshi

2023

Luminescence

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Zinc oxide (ZnO) has several industrial applications due to its versatile properties, which lead to its continuously increasing demand in different industrial sectors. Additionally, ZnO nanostructures possess unique photocatalytic activity, and because of this, they are being applied to degrade organic dyes through photocatalysis for wastewater treatment. Nevertheless, chemical synthesis methods to develop ZnO nanostructures have raised concerns related to environmental issues, furthermore, these methods are found to be costly and tedious. As a result, the synthesis of ZnO nanostructures using green methods is gaining popularity due to its low cost and eco‐friendly mode, while avoiding the use of toxic chemicals. Green synthesis of ZnO nanostructures using different biological approaches involving plants, algae, and different microorganism‐derived bioactive compounds has been well reported for diverse applications. Among different applications, ZnO nanostructures that enable photocatalysis to degrade dye have been found to be imperative for wastewater treatments. Therefore, the current review explores recent studies on green synthesis approaches to prepare ZnO nanostructures via adopting different biological methods that rely on plants, algae, and bacterial microorganisms. The properties of ZnO nanostructures, along with their green synthesis routes and feasible mechanisms, have also been discussed in this review. This review focuses on the use and efficiency of green route synthesized ZnO nanostructures as nanophotocatalysts for the degradation of organic dyes in wastewater treatment. Additionally, existing challenges in green synthesis methods and the efficiency of ZnO nanostructures to degrade organic dyes following photocatalysis has been discussed.

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Biofabrication and characterization of cyanobacteria derived ZnO NPs for their bioactivity comparison with commercial chemically synthesized nanoparticles

Cited by 27 publications

References 58 publications

Toxicological assessment of Phormidium sp. derived copper oxide nanoparticles for its biomedical and environmental applications

Toxicological assessment of Phormidium sp. derived copper oxide nanoparticles for its biomedical and environmental applications

Algal Extracts for Green Synthesis of Zinc Oxide Nanoparticles: Promising Approach for Algae Bioremediation

A review on biological synthesis of ZnO nanostructures and its application in photocatalysis mediated dye degradation: An overview

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