Biofilm Formation of Panresistant Klebsiella Pneumoniae

Abstract

Introduction: The authors aimed to investigate the biofilm-forming features of panresistant Klebsiella pneumoniae (PRKp). Material & methods: The biofilm formations were shown under light microscope and laser scanning confocal microscopy. The optical densities of the wells were measured and classified according to biofilm-forming capacities. Results: The ratio of biofilm-forming K. pneumoniae was established to be 100%. All isolates were found to form high-level biofilms in classification compared with positive and negative controls. No significant difference was detected in the biofilm-forming capacities of K. pneumoniae strains isolated from different sample types. Conclusion: No previous study associated with PRKp isolates was identified in the literature search. There is a need for different approaches characterizing the biofilm-forming features of PRKp.

Relationship between biofilm formation and antibiotic resistance of Klebsiella pneumoniae and updates on antibiofilm therapeutic strategies

“…Ashwath et al found that 97.1% of the clinically multidrugresistant (MDR) K. pneumoniae isolates formed biofilms, and the isolates from blood, pus and trachea secretions were more capable of forming biofilms (Ashwath et al, 2022). Tuncer et al investigated biofilm-forming features of pan-resistant (resistant to all agents) K. pneumoniae and found that all the isolates formed high-level biofilms, whereas no significant difference was detected for the isolates obtained from different samples (blood, sputum and wound) (Tuncer et al, 2022). Differences between different studies may attribute to geographic regions, sample types and numbers, and bacterial antibiotic resistance.…”