2010
DOI: 10.4103/0974-2077.63257
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Biofilms: Their role in dermal fillers

Abstract: Fillers are commonly used in several aesthetic indications. Though considered safe, several side effects have been reported. The role of biofilms in the causation of some of these side effects has been elucidated only recently and this article presents a short review of the subject.

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Cited by 37 publications
(18 citation statements)
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“…Although they are usually culture negative, biofilms often resolve with antibiotic treatment and bacteria can be observed in biopsy specimens. Precautionary measures to prevent the formation of biofilms include using antiseptic solution before the filler injection, local application of mupirocin, and some recommend the use of prophylactic antimicrobial therapy with a single dose of broad‐spectrum antibiotics …”
Section: Resultsmentioning
confidence: 99%
“…Although they are usually culture negative, biofilms often resolve with antibiotic treatment and bacteria can be observed in biopsy specimens. Precautionary measures to prevent the formation of biofilms include using antiseptic solution before the filler injection, local application of mupirocin, and some recommend the use of prophylactic antimicrobial therapy with a single dose of broad‐spectrum antibiotics …”
Section: Resultsmentioning
confidence: 99%
“…Biofilms can even exist on the inside of needles that are used to inject filler . Infections after filler injection are more common with long‐acting, hydrophilic fillers.…”
Section: Biofilm Causing Infectionmentioning
confidence: 99%
“…Trace amounts of protein in the HA raw material were reduced approximately 6 times lower than the original raw material. 13 9 A recent review of reported hypersensitivity reactions speculated that most of the reported hypersensitivity reactions were likely due to an infectious process.…”
Section: Etiology Of Soft-tissue Reactionsmentioning
confidence: 99%