Biogenic Silver Nanoparticles: What We Know and What Do We Need to Know?

Abstract

Nanobiotechnology is considered to be one of the fastest emerging fields. It is still a relatively new and exciting area of research with considerable potential for development. Among the inorganic nanomaterials, biogenically synthesized silver nanoparticles (bio-AgNPs) have been frequently used due to their unique physicochemical properties that result not only from their shape and size but also from surface coatings of natural origin. These properties determine antibacterial, antifungal, antiprotozoal, anticancer, anti-inflammatory, and many more activities of bio-AgNPs. This review provides the current state of knowledge on the methods and mechanisms of biogenic synthesis of silver nanoparticles as well as their potential applications in different fields such as medicine, food, agriculture, and industries.

A novel antibacterial and antifouling nanocomposite coated endotracheal tube to prevent ventilator-associated pneumonia

“…In addition, the increase in cell density enhances the effect of quorum sensing, causing genetic mutations that reduce the metabolic activity; in other words, a combative environment increases the phenotypic variation between bacteria, thereby providing favorable defense and progress, ultimately leading to antibiotic resistance [ 32 , 33 ]. Biofilm formation on the surfaces of medical devices is therefore a key feature of disease progression, and so the antiadhesion and antibacterial functionalization of PVC-ETTs with hydrophilic polymers and stable broad-spectrum antibacterial agents is particularly important in the prevention of biofilm formation and bacterial infection [ 34 – 37 ]. It is therefore also critical to suppress bacterial adhesion and multiplication during the initial stage.…”

Promising antimicrobials from Phoma spp.: progress and prospects

“…exigua, P. sorghina, P. macrostoma, P. glomerata, P. macdonaldii, P. tracheiphila, P. multirostrata, P. proboscis, and P. foveata , etc. (Rai et al 2009a , b , c , 2021a , b ). As shown in Fig.…”

The Effect of Vitamin D3 and Silver Nanoparticles on HaCaT Cell Viability

“…An open gap of 0.9 mm was created by a "wound", as reported in the Section 4. The reaction of the cells to fill the damaged area was inspected microscopically over time (6,12, and 18 h) (Figure 2). In the control sample, the open gap remained unchanged after 6 h (0.9 mm), with a reduction of 25% and 60% after 12 h and 18 h, respectively.…”

“…It has been demonstrated that silver nanoparticles (AgNPs) are useful for different medical applications as medical products, medical instruments, water filtration, personal hygiene products, and others [11]. AgNPs are well known for their unique physical, chemical, and biological properties, which depend on their size, shape, and surface charge [12]. Thanks to their size (1-100 nm), the particles enter cells mostly through endocytosis and release of ions into the cytoplasm [13].…”

“…Thanks to their size (1-100 nm), the particles enter cells mostly through endocytosis and release of ions into the cytoplasm [13]. The antibacterial, antiviral, antifungal, antiprotozoal, antiparasitic, and anticancer efficacy of AgNPs has been demonstrated [12]. Interestingly, AgNPs also have antioxidant properties [14].…”