Bioimpedance Measurement of Knee Injuries using Bipolar Electrode Configuration

Abstract

Currently, there is no suitable solution for the point-of-care of knee injuries. A potential portable and low-cost technique for accessing and monitoring knee injuries is bioimpedance measurement. This study validated the feasibility of the bipolar electrode configuration for knee bioimpedance measurements with two electrodes placed on a fixed pair of knee acupuncture locations called Xiyan. Then, the study collected 82 valid samples to investigate the relationship between bioimpedance and knee injuries, among whom 45 patients, each with one healthy knee and one injured knee, and 37 individuals all with healthy knees. The self-contrast results indicated that knee injuries caused a reduction of bioimpedance of the knee by about 5% on average, which was detectable at around 100 kHz (p ≈ 0.001). Furthermore, the results analyzed by principal component analysis and support vector machines show that the detection sensitivity can reach 91.11% using the leave-one-out cross-validation.

Localized Multi-Site Knee Bioimpedance as a Predictor for Knee Osteoarthritis Associated Pain Within Older Adults During Free-Living

“…al. investigated the differences in impedance metrics from injured and healthy knees, with injury classifications ranging from osteoarthritis to ACL tears [21]. They reported statistically significant relative impedance differences between groups from 46.4 kHz to 1 MHz.…”