Biologic mesh versus synthetic mesh in open inguinal hernia repair: system review and meta‐analysis

Abstract

From the data of this study, biologic mesh had no superiority to synthetic mesh in open inguinal hernia repair with similar recurrence rates and incidence of chronic groin pain, but higher rate of seroma and longer operating time. However, this mesh still needs to be assessed in a large, multicentre, well-designed randomized controlled trial.

Evaluation of resorbable polydioxanone and polyglycolic acid meshes in a rat model of ventral hernia repair

“…For more than half a century, researchers have been looking for the ideal material for hernioplasty: many studies have been published that analyze effectiveness and safety of prosthetics in connection with the origin of the material (biological vs. synthetic), rate of resorption, structure (mono-vs. multi-filament), and so forth. 1,2,[9][10][11] The advantages of using resorbable/biodegradable prostheses instead of non-resorbable prostheses are questionable. 9,10 On one hand, the prosthesis represents a physical cause of various postoperative complications such as fibrosis, chronic pains, and fistula formation; therefore, its complete dissolution is favorable.…”

“…By probabilities of hernia recurrence and other postoperative complications, the resorbable decellularized tissue-based prostheses turned out to be comparable or inferior to their synthetic counterparts. [9][10][11] The foreign body inflammatory reaction develops independently of the nature of implanted material, either animal tissue-derived, or synthetic. 12 An additional drawback is due to the fact that obtaining of tissue-derived prostheses with appropriate biomechanical properties (i.e., strong enough to withstand the anatomical load) requires artificial introduction of additional cross-links into collagen molecules, which leads to considerable compaction of the material and decreases its porosity, impedes tissue ingrowth, and compromises the engraftment.…”

Biological Meshes for Inguinal Hernia Repair – Review of the Literature

“…For two RCTs, only an abstract is available ( 8 , 9 ). Recently, two meta-analyses were also published reporting on three and four RCTs, respectively ( 12 , 13 ). Furthermore, there are five retrospective case series available ( 14 – 18 ), in which biological meshes had been used to repair inguinal hernias and the corresponding follow-up results reported (Table 2 ).…”

Defining the characteristics of certified hernia centers in Italy: The Italian society of hernia and abdominal wall surgery workgroup consensus on systematic reviews of the best available evidences

“…Table 6 shows the characteristics of selected studies. The reported value for SSI ranged from 0% to 6.0% [60,[66][67].…”

“…The primary search found 1466 references, of which 38 met the inclusion criteria and 2 added by crossreferencing. Mean AMSTAR score of these papers was 6.9, Values were extracted from the highest scoring 14 studies [51][52][53][54][55][56][58][59][60][63][64][65][66][67]. Table 7 shows the characteristics of selected studies.…”