Biologic Responses to Polyetheretherketone (PEEK) Wear Particles

Stratton‐Powell, Ashley A.; Pasko, Kinga M.; Lal, Saurabh; Brockett, Claire; Tipper, Joanne L.

doi:10.1016/b978-0-12-812524-3.00022-3

Cited by 2 publications

(2 citation statements)

References 42 publications

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“…By over-tightening the screws, this process could result in the creation of PEEK particles. PEEK particles have been shown to be proinflammatory in vitro 14 . In addition, there is a previous case report of a carbon fiber-infused PEEK plate used for a distal radius fracture that created a proinflammatory response resulting in extensive synovitis and flexor tendon destruction 17 .…”

Section: Discussionmentioning

confidence: 99%

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A Failed 4-Corner Arthrodesis Using a Polyether-Ether-Ketone Implant

London

Stern

2021

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Case: A 59-year-old man underwent scaphoidectomy and 4-corner arthrodesis with a polyether-ether-ketone (PEEK) circular plate for scapholunate advanced collapse of the wrist. Five years later, he presented with a symptomatic nonunion and radiocarpal arthritis. Total wrist arthrodesis with a dorsal plate was performed. During revision surgery, considerable synovitis was encountered. Histological evaluation revealed a foreign body response likely secondary to PEEK particles. Conclusion: Use of PEEK implants can result in an adverse local tissue reaction if particles are generated. This is a rare biomaterial-related complication, and surgeons should be aware of this adverse tissue response when using this or other PEEK implants.

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Section: Discussionmentioning

confidence: 99%

“…One hallmark of PEEK is that it is an inert, biocompatible material when solid. However, when implants undergo wear, PEEK particles have been shown to create an inflammatory/immune response in vitro 14 .…”

mentioning

confidence: 99%

A Failed 4-Corner Arthrodesis Using a Polyether-Ether-Ketone Implant

London

Stern

2021

JBJS Case Connector

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Surface Treatment of Additively Manufactured Polyetheretherketone (PEEK) by Centrifugal Disc Finishing Process: Identification of the Key Parameters

Zentgraf,

Nützel,

Mühlbauer

et al. 2024

Polymers

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Polyetheretherketone is a promising material for implants due to its good mechanical properties and excellent biocompatibility. Its accessibility to a wide range of applications is facilitated by the ability to process it with an easy-to-use manufacturing process such as fused filament fabrication. The elimination of disadvantages associated with the manufacturing process, such as a poor surface quality, is a main challenge to deal with. As part of the mass finishing process, centrifugal disc finishing has demonstrated good results in surface optimization, making it a promising candidate for the post-processing of additively manufactured parts. The objective of this study is to identify the key parameters of the centrifugal disc finishing process on the waviness of additively manufactured PEEK specimens, which has not been investigated previously. The waviness of the specimen was investigated by means of confocal laser scanning microscopy (CLSM), while weight loss was additionally tracked. Six parameters were investigated: type, amount and speed of media, use of compound, amount of water and time. Type of media, time and speed were found to significantly influence waviness reduction and weight loss. Surface electron microscopy images demonstrated the additional effects of deburring and corner rounding. Results on previous studies with specimens made of metal showed similar results. Further investigation is required to optimize waviness reduction and polish parts in a second post-processing step.

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Biologic Responses to Polyetheretherketone (PEEK) Wear Particles

Cited by 2 publications

References 42 publications

A Failed 4-Corner Arthrodesis Using a Polyether-Ether-Ketone Implant

A Failed 4-Corner Arthrodesis Using a Polyether-Ether-Ketone Implant

Surface Treatment of Additively Manufactured Polyetheretherketone (PEEK) by Centrifugal Disc Finishing Process: Identification of the Key Parameters

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