Biological activities, chromatographic profile and thermal stability of organic and conventional goji berry

Pedro, Alessandra Cristina; Pérez-Rodríguez, María Luisa; Sánchez-Mata, María Cortes; Bisinella, Radla Zabian Bassetto; Oliveira, Cristina Soltovski de; Schnitzler, Egon; Bet, Camila Delinski; Maciel, Giselle Maria; Haminiuk, Charles Windson Isidoro

doi:10.1007/s11694-021-01274-1

Cited by 6 publications

(10 citation statements)

References 56 publications

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“…Additionally, drying, storage, solvent and extraction method affect bioactive compound concentration. 76,101,102 These effects were evident in comparing the cytotoxic activity of goji berry extract observed by different authors. Thus, goji berry extract produced by ultrasound (6.71 min, 45 °C) demonstrates high cytotoxic effects, showing its potential in cancer treatment.…”

Section: Cytotoxic Activitymentioning

confidence: 78%

“…Pedro et al 76 also observed high concentrations of phenolic compounds for the extracts of goji berry, and ultrasound showed higher indices than shaker. However, the results did not indicate a significant difference between them.…”

Section: Comparison Of the Shaker And Ultrasound-assisted Extraction ...mentioning

confidence: 94%

“…In addition, the authors also reported low concentrations of carotenoids. 76 Ilić et al 65 compared three different varieties of Lycium barbarum, and the concentrations of phenolic compounds ranged between 162.4 and 295.7 mg GAE 100 g −1 . Flavonoid analysis was performed using a different pattern from the present study but also presented high indices of these compounds.…”

Section: Comparison Of the Shaker And Ultrasound-assisted Extraction ...mentioning

confidence: 99%

“…However, studies prove the antioxidant activity of the fruit and high levels of bioactive compounds. 7,65,73,76 Thus, it is interesting to evaluate the extraction kinetics to determine if there was degradation of the compounds throughout the process, to assess yield at different times, to describe the kinetic behavior of the extraction and to define which of the methods was more efficient.…”

Section: Comparison Of the Shaker And Ultrasound-assisted Extraction ...mentioning

confidence: 99%

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Optimization of extraction of bioactive compounds with antiproliferative activity from goji berry and assessment of kinetic models

Peixoto,

Raimundini Aranha,

Oliveira Defendi

et al. 2023

J of Chemical Tech & Biotech

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This work aims to optimize the extraction of bioactive compounds with antiproliferative activity of goji berry (Lycium barbarum) and assess the extraction kinetic models. The extraction was performed by varying the proportion of ethanol:water solvent. The antioxidant activity determination tests indicated a significant difference for the proportion of 60:40 ethanol:water. Conditions of the highest levels of antioxidant activity at 45 °C and 6.71 min for ultrasound and at 45 °C and 23.30 h for shaker. The quantification of phenolic compounds, flavonoids, carotenoids, and anthocyanins showed that the ultrasound method led to the highest concentrations of these compounds. The extraction kinetics was evaluated, and the So and Mac Donald's and Second Order models showed the best fit, with a global maximum deviation lower than 10.0%. High concentrations of extracts produced showed cytotoxic effects for human hepatoma cells by the MTT test. The extract produced by Ultrasound reached cell viability of 37.71%.This article is protected by copyright. All rights reserved.

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Section: Cytotoxic Activitymentioning

confidence: 78%

Section: Comparison Of the Shaker And Ultrasound-assisted Extraction ...mentioning

confidence: 94%

Section: Comparison Of the Shaker And Ultrasound-assisted Extraction ...mentioning

confidence: 99%

Section: Comparison Of the Shaker And Ultrasound-assisted Extraction ...mentioning

confidence: 99%

See 2 more Smart Citations

Optimization of extraction of bioactive compounds with antiproliferative activity from goji berry and assessment of kinetic models

Peixoto,

Raimundini Aranha,

Oliveira Defendi

et al. 2023

J of Chemical Tech & Biotech

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“…The determination of total polyphenols (Q-Fast Blue BB) was carried out according to the methodology described by Arias-Rico et al (2020) and Pedro et al (2022) in order to avoid the interferences of reducing compounds with the FC method [ 45 , 46 ]. This method is based on the direct interaction between phenolics and the diazonium salt, present in the reagent Fast Blue BB, but ascorbic acid and other reducing compounds do not react with the diazonium salt, this method being the best choice for measuring TPC in foods containing reducing substances.…”

Section: Methodsmentioning

confidence: 99%

Dwarf Kiwi (Actinidia arguta Miq.), a Source of Antioxidants for a Healthy and Sustainable Diet

et al. 2022

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The feasibility of using dwarf kiwi fruits (Actinia arguta Miq.) as a healthy and sustainable food, compared to other types of commercial kiwi fruits, was evaluated in the present study. The overall antioxidant capacity of these fruits was assessed by either extraction-dependent methods (ABTS, ORAC) or the direct method called Quick, Easy, New, CHEap, Reproducible (QUENCHER) (DPPH, FRAP, Folin–Ciocalteu), applied for the first time to analyze kiwi fruits. With this methodology, all the molecules with antioxidant capacity are measured together in a single step, even those with high molecular weight or poor solubility in aqueous extraction systems, such as antioxidant dietary fiber. The effect of kiwi extracts on physiological and induced intracellular reactive oxygen species (ROS) production on IEC-6 cells was also analyzed, as well as total phenolic content (TPC) by Fast Blue BB, flavonols, hydroxycinnamic acids, and hydroxybenzoic acids. A. arguta fruits showed the highest values in all the antioxidant assays, being remarkably higher than the other kiwi species for Q-FRAP and Q-DPPH. Dwarf kiwi showed the highest potential in reducing physiological ROS and the highest values of TPC (54.57 mgGAE/g), being hydroxybenzoic acids the main phenolic family found (2.40 mgGAE/g). Therefore, dwarf kiwi fruits are a natural source of antioxidants compared to conventional kiwi fruits, being a sustainable and healthy alternative to diversify fruits in the diet.

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Nutritional Value, Phytochemical Composition and Biological Activities of Lycium barbarum L. fruits from Serbia

Ilić,

Đuričić,

Kodranov

et al. 2024

Plant Foods Hum Nutr

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Biological activities, chromatographic profile and thermal stability of organic and conventional goji berry

Cited by 6 publications

References 56 publications

Optimization of extraction of bioactive compounds with antiproliferative activity from goji berry and assessment of kinetic models

Optimization of extraction of bioactive compounds with antiproliferative activity from goji berry and assessment of kinetic models

Dwarf Kiwi (Actinidia arguta Miq.), a Source of Antioxidants for a Healthy and Sustainable Diet

Nutritional Value, Phytochemical Composition and Biological Activities of Lycium barbarum L. fruits from Serbia

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