Biological activity of essential oils and their constituents

Nakatsu, Tetsuo; Lupo, Andrew T.; Chinn, John W.; Kang, Raphael

doi:10.1016/s1572-5995(00)80014-9

Cited by 139 publications

(98 citation statements)

References 139 publications

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“…12 A number of studies and reviews have been conducted on phytochemical as natural antimicrobial agent due to the increasing consumer demand for safer food additive. 4,5,9,[12][13][14][15][16][17] Tana et al 5 brings to the fore the fact that antimicrobial activity is depending on the compounds concentration, structure, functional group and composition. Even though study by Ciocan and Bara 12 highlighted that essential oil have been used worldwide as food preservative since ancient times and alkaloids also commonly used as antimicrobial agent in foods product, however study by Halley and Patel 18 highlighted that phenolic compounds are the most effective phytochemical.…”

Section: Antimicrobial Activity Of Malaysian Plantsmentioning

confidence: 99%

“…12 In addition tofragrance provider in plants, EO also getting their fame from theirrole in spices flavor and aroma. 5 Essential oil are typically found in compounds with isoprene structures such as terpenes with general chemical structure C 10 H 16 , diterpenes (C 20 ), triterpenes (C 30 ), tetraterpenes (C 40 ), hemiterpenes (C 5 ) and sesquiterpenes (C 15 ). When the compounds contain additional element, typically oxygen, it is known as terpenoids.…”

Section: Antimicrobial Activity Of Malaysian Plantsmentioning

confidence: 99%

“…Other than structural composition, the methods used to extractthe antimicrobial compound also affects the antimicrobial compound efficacy. 16,17,46 …”

Section: Antimicrobial Activity Of Malaysian Plantsmentioning

confidence: 99%

See 2 more Smart Citations

Antimicrobial agents from Malaysian plants and their potential use in food packaging material: Review

Mustapha¹,

Jai²,

Hamidon³

et al. 2017

Chem. Eng. Res. Bull.

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Malaysia is among 12 countries in the world that rich in biodiversity including an assortment of plants with potential sources for new antimicrobial agents. Despite the fact that various plants have been screened, the requirement for detail study on antimicrobial compounds from plants is preceded as safer and better agent to inhibit growth of microbes. Therefore, selected Malaysia plants with medicinal properties are listed for further review in their antimicrobial activity and their major compound that act as antimicrobial agent. The major groups of the antimicrobial constituents are phenolics, phenolic acids, quinones, saponins, flavonoids, tannins, coumarins, terpenoids and alkaloids. These compounds are secondary metabolites that play the main role in plant defense mechanism. They also exhibited inhibitory effect on various microorganisms such as Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli and Candida albicans. Compounds derived from Malaysian plants have the potential to be used as antimicrobial additive as most of their extracts containing active compounds such as caffeic acid, pyrogallol, catechin and curcumin. Extraction method of plants extract is done either by conventional method of maceration and extraction under reflux and steam distillation or modern method of microwave assisted extraction, supercritical fluid extraction and ultrasound-assisted solvent extraction. Even though plants extracts with medicinal properties are gaining fame for their antimicrobial properties, however the study on incorporation of the extracts into edible films as antimicrobial food packaging is limited. The advantages of using an edible film with antimicrobial agent plants for food products are it safe to use and it able to extend the shelf life while reducing packaging waste.

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Section: Antimicrobial Activity Of Malaysian Plantsmentioning

confidence: 99%

Section: Antimicrobial Activity Of Malaysian Plantsmentioning

confidence: 99%

See 1 more Smart Citation

Antimicrobial agents from Malaysian plants and their potential use in food packaging material: Review

Mustapha¹,

Jai²,

Hamidon³

et al. 2017

Chem. Eng. Res. Bull.

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“…Varias razones apoyan la búsqueda de compuestos bioactivos de origen natural entre las cuales están su fácil obtención, su susceptibilidad para ser modificados y sintetizar compuestos potencialmente más activos y seguros que los actuales, así como el valor económico que representa su utilización y aprovechamiento no solo para la industria farmacéutica sino para diversas industrias como la química que puede aplicar los conocimientos generados de este estudio en la producción de diversas sustancias que controlen el crecimiento y multiplicación del microorganismo y puedan ser comercializadas en diferentes presentaciones como desinfectantes y detergentes entre otros (Bueno-Sánchez et al, 2011ª, Bueno-Sánchez y Kouznetzov, 2010Stashenko, 2010;Ajikumar et al, 2008;Verpoorte et al, 2006;Nakatsu et al, 2000;Cowan, 1999 …”

Section: Justificaciónunclassified

Search for synthetic and natural substances with in vitro bioactivity against Mycobacterium tuberculosis. Part I

Moreno¹,

Ribón²

2017

JOSHA

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“…Many essential oils are known for their antimicrobial properties and are considered the most widely used natural product to date (Nakatsu et al 2000). The use of herbal extracts is widely expected to become an alternative therapy in aquaculture as a prophylactic and to control fish diseases.…”

Section: Introductionmentioning

confidence: 99%

In vitro activity of some essential oils alone and in combination against the fish pathogen Nocardia seriolae

Ismail¹,

Yoshida²

2017

Polish Journal of Veterinary Sciences

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Microplate resazurin assay was applied to investigate the in vitro activity of four essential oils (EOs); cinnamon (Cinnamomum zeylanicum), thyme (Thymus vulgaris), lemongrass (Cymbopogon flexuosus) and tea tree (Melaleuca alternifolia) oils against 80 clinical isolates of the fish pathogen Nocardia seriolae. The checkerboard test was then used to determine the possible synergistic effect of EOs combination against reference type strains of fish nocardiosis. All tested EOs had antibacterial activity against N. seriolae isolates. Among the tested EOs, cinnamon and thyme oils both exhibited the lowest minimum inhibitory concentrations (MICs) with 5-160 and 10-160 μg/ml, respectively. The activities of lemongrass and tea tree EOs were noted to be less effective with MICs of 20-640 and 160->5120 μg/ml, respectively. The checkerboard panel of cinnamon-thyme EOs combination against N. seriolae ATCC43993 demonstrated a synergistic effect with a fractional inhibitory concentration (FIC) index of 0.75. For N. salmonicida ATCC27463, the combination panel showed an additive effect with an FIC index of 1.0. For N. asteroides ATCC19247, the combination panel demonstrated an indifference effect with an FIC index of 1.125. These results indicate that thyme and cinnamon oils alone or the combination of them at a given ratio has a promising potent clinical significance in the treatment of fish nocardiosis. Despite the promising results given by our in vitro studies, the clinical benefits of these EOs combinations can only be determined through carefully designed in vivo experimental studies.

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Biological activity of essential oils and their constituents

Cited by 139 publications

References 139 publications

Antimicrobial agents from Malaysian plants and their potential use in food packaging material: Review

Antimicrobial agents from Malaysian plants and their potential use in food packaging material: Review

Search for synthetic and natural substances with in vitro bioactivity against Mycobacterium tuberculosis. Part I

In vitro activity of some essential oils alone and in combination against the fish pathogen Nocardia seriolae

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