Biological activity of some Patagonian plants

Cuadra, Pedro; Furrianca, María Cristina; Oyarzún, Alejandra; Yáñez, Erwin; Gallardo, Amalia; Fajardo, Víctor

doi:10.1016/j.fitote.2005.07.007

Cited by 9 publications

(6 citation statements)

References 18 publications

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“…But while toxicity assays are available for many countries (e.g. Argentina (Bustos et al, 1996; Hernández et al, 2000), Bahrain (Taha and Alsayed, 2000), Bangladesh (Costa-Lotufo et al, 2005), Brazil (Hammer and Johns, 1993; Alves et al, 2000; Holetz et al, 2002; Santos Piemanta et al, 2003; Quignard et al, 2004; Ferreira de Lima et al, 2006; Suffredini et al, 2006; dos Santos et al, 2007), Canada (McCuthcheon, 1992), Chile (Cuadra et al, 2005), China (Duffy and Power, 2001), Cuba (Martinez et al, 1996; Logarto Parra et al, 2001), Ecuador (Guerrero et al, 2003), Guatemala (Cáceres et al, 1993a, b, 1998; Michel et al, 2007), Honduras (Lenz et al, 1998), India (Padmaja et al, 2002), Kenya (Kirira et al 2006; Wanyoike et al, 2004), Mexico (Sánchez-Medina et al, 2001), Nicaragua (Coe et al 2010), Nigeria (Ajaiyeoba et al, 2006), Panama (Sánchez et al, 1993), Papua New Guinea (Nick et al, 1995), Philippines (Horgen et al, 2001), Uruguay (González et al, 1993), USA (Turker and Camper, 2002; Badisa et al, 2007; Van Slambrouck et al, 2007), no data exists on the potential toxicity of Peruvian medicinal species.…”

Section: Introductionmentioning

confidence: 99%

Toxicity of medicinal plants used in traditional medicine in Northern Peru

Bussmann

Malca²,

Glenn

et al. 2011

Journal of Ethnopharmacology

476

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Aim The plant species reported here are traditionally used in Northern Peru for a wide range of illnesses. Most remedies are prepared as ethanol or aqueous extracts and then ingested. The aim of this study was to evaluate the potential toxicity of these extracts. Materials and methods The toxicity of ethanolic and water extracts of 341 plant species was determined using a Brine-Shrimp assay. Results Overall 24% of the species in water extract and 76% of the species in alcoholic extract showed elevated toxicity levels to brine-shrimp. Although in most cases multiple extracts of the same species showed very similar toxicity values, in some cases the toxicity of different extracts of the same species varied from non-toxic to highly toxic. Conclusions Traditional preparation methods take different toxicity levels in aqueous and ethanol extracts into account when choosing the appropriate solvent for the preparation of a remedy.

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Section: Introductionmentioning

confidence: 99%

Toxicity of medicinal plants used in traditional medicine in Northern Peru

Bussmann

Malca²,

Glenn

et al. 2011

Journal of Ethnopharmacology

476

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“…salina property showing LC 50 as low as of 0.13 µg/mL (Pimenta et al, 2003;Cuadra et al, 2005). Still, sesquiterpenes, triterpenes, esterols, tanins e alkaloidscontaining Indian plants presented LC 50 against A. salina ranging from 6.9 to 579 µg/mL (Padmaja et al, 2002).…”

Section: Discussionmentioning

confidence: 99%

Preliminary study of the molluscicidal and larvicidal properties of some essential oils and phytochemicals from medicinal plants

Leite¹,

Lima²,

Souza³

et al. 2009

Rev. bras. farmacogn.

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RESUMO: "Estudo preliminar das propriedades moluscicidas e larvicidas de alguns óleosABSTRACT: This study aimed to evaluate the molluscicidal and larvicidal activity of some essential oils and phytochemicals from medicinal plants. Molluscicide and larvicidal activity were determined by, respectively, the lethality bioassays using Artemia salina Leach. Artemiidae and Aedes aegypti L. Culicidae larvae. Essential oils from Eugenia uniflora L. Myrtaceae, Laurus nobilis L. Lauraceae, Origanum vulgare L. Lamiaceae and the phytochemicals α-pinene and eugenol presented citotoxicity toward Artemia salina with CL 50 values between 9.59 and 253.43 µL/mL. Essential oils from E. uniflora, M. piperita, O. vulgare and R. officinalis showed embryotoxicity on Aedes aegypti larvae with a viability inhibition between 40 and 100%. These results show the bioactivity of the assayed essential oils and phytochemicals and, partially, justify their insertion in further evaluation in order to establish a safe exploitation of their biological potentiality.

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“…obconicum extracts were considered almost non-toxic, the n-hexane extract is on the limit with a LD50 value of 934.5 ± 56.2 μg·mL −1 . Samples rich in flavonoids are known to possess low LD50 values against Artemia salina [29,30]. Several flavonoids were identified in H. devium [13] and H. melaleucum [17], while H. obconicum was rich in quinic acid derivatives [18].…”

Section: Artemia Salina Toxicitymentioning

confidence: 99%

Performance Evaluation of Bidding-Based Multi-Agent Scheduling Algorithms for Manufacturing Systems

Gordillo¹,

Giret

2014

Machines

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Abstract:The potential bioactivity of dietary and medicinal endemic Helichrysum plants from Madeira Archipelago was explored, for the first time, in order to supply new information for the general consumer. In vitro antioxidant properties were investigated using DPPH, ABTS•+ , FRAP and β-Carotene assays, and the total phenolic content (TPC) and total flavonoid content (TFC) were also determined. Although the results generally showed a large variation among the three analyzed plants, the methanolic extracts showed the highest antioxidant capacity. Exception is made for H. devium n-hexane extract that showed good radical scavenger capacity associated to compounds with good reducing properties. In the Artemia salina toxicity assay and antimycobaterial activity, H. devium was the most potent plant with the lowest LD50 at 216.7 ± 10.4 and MIC ≤ 50 μg·mL 714(Principal Component Analysis-PCA) showed close interdependence between the ABTS, TPC and TFC methods and allowed to group H. devium samples.

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Biological activity of some Patagonian plants

Cited by 9 publications

References 18 publications

Toxicity of medicinal plants used in traditional medicine in Northern Peru

Toxicity of medicinal plants used in traditional medicine in Northern Peru

Preliminary study of the molluscicidal and larvicidal properties of some essential oils and phytochemicals from medicinal plants

Performance Evaluation of Bidding-Based Multi-Agent Scheduling Algorithms for Manufacturing Systems

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